ABSTRACT
Objetivo: Investigar por meio de questionário os aspectos psicológicos e sociais de pacientes inférteis atendidas no 1 ⦠Mutirão de Infertilidade do Hospital Electro Bonini, em Ribeirão Preto (SP). Métodos: Foram entrevistadas 116 mulheres que procuraram atendimento para investigação e tratamento de infertilidade. Os resultados foram analisados para identificação do perfil psicossocial das pacientes. Resultados: Os principais questionamentos levaram em conta grau de tristeza por não engravidar, esperança de engravidar, se já engravidou, se já pensou em adotar filhos, desistência do tratamento. Os resultados foram condizentes com os dados encontrados na literatura. A análise do perfil biopsicossocial nos revelou o acentuado grau de tristeza e preconceito ou pressão social por não conseguir engravidar. Entretanto, essas mulheres demonstram grande esperança de gestar e a maioria não pensa em desistir do tratamento. Conclusão: Este estudo comprova o aspecto patológico que a infertilidade ocasiona na vida dos casais, principalmente nas mulheres, já que 75% relataram que se sentem infelizes ou depressivas por não conseguirem engravidar. O trabalho multidisciplinar, nesse sentido, é de fundamental importância na compreensão dos conflitos emocionais íntimos e profundos que a infertilidade provoca.(AU)
Objective: To investigate, through a questionnaire, the psychological and social aspects of infertile patients attended at the Infertility Ambulatory Clinic of Electro Bonini Hospital, in the city of Ribeirão Preto (SP). Methods: Were interviewed 116 women who sought care for investigation and treatment of infertility. The results were analyzed to identify the social and psychological profiles of the patients. Results: The main questions took into accountthe degree of sadness for not getting pregnant, their hope to get pregnant, if they had already been pregnant, if they had ever thought about adopting a child, withdrawal of treatment. The results were consistent with the data found in the literature. The biopsychosocial profile analysis revealed a strong degree of sadness and prejudice or social pressure for not getting pregnant. However, those women have great hope of getting pregnant and the vast majority doesn't think of quitting treatment. Conclusion: This study proves the pathological aspect that infertility causes in the lives of couples, especially women, since 75% reported that they feel unhappy or depressed for not being able to get pregnant. Multidisciplinary work, in that sense, plays an important role in understanding the intimate and deep emotional conflicts that infertility causes.(AU)
Subject(s)
Humans , Female , Adult , Middle Aged , Young Adult , Fertilization in Vitro/methods , Health Profile , Infertility/epidemiologyABSTRACT
Mesenteric lymphadenitis is a clinical condition that affects mostly children and teenagers. Its symptoms include fever, severe abdominal pain, nausea, and, in some cases, diarrhea, constipation, and acute abdomen. This paper describes the case of a 16-year-old patient with mesenteric lymphadenitis submitted to an exploratory laparoscopy for suppurative lymph nodes that evolved to a drastic reduction of ovarian reserve. Because of the patients age, she was offered cryopreservation of her ovarian tissue.
Subject(s)
Infertility, Female , Mesenteric Lymphadenitis , Ovarian Reserve/physiology , Abdomen, Acute/diagnostic imaging , Abdomen, Acute/etiology , Adolescent , Cryopreservation , Female , Humans , Infertility, Female/etiology , Infertility, Female/therapy , Mesenteric Lymphadenitis/complications , Mesenteric Lymphadenitis/diagnostic imaging , Mesenteric Lymphadenitis/surgery , UltrasonographyABSTRACT
Justificativa: A resposta ao estímulo ovariano é uma peça-chave na reprodução assistida. Apesar dos recentes avanços das técnicas, pacientes com baixa reserva ovariana apresentam mau prognóstico e representam um desafio na medicina reprodutiva. Objetivo: Propor estratégia de melhoria do prognóstico reprodutivo em mulheres com idades superiores a 38 anos ou jovens com baixa contagem de folículos antrais, por meio do uso de testosterona previamente ao estímulo ovariano. Material e métodos: Levantamento de dados da literatura científica na área da medicina reprodutiva. Resultados e conclusões: O uso de androgênios em fases que antecedem a estimulação ovariana em ciclos de fertilização in vitro parece ser ótima ferramenta de melhoria da resposta à estimulação oocitária controlada em pacientes com mais de 38 anos ou com reserva ovariana diminuída. Melhora tanto a quantidade quanto a qualidade oocitária e aumenta as taxas de gestação e de nascido vivos.
Justification: The response to ovarian stimulation is a keyelement in assisted reproduction (AR). Despite recent advances in the techniques, patients with low ovarian reserve havepoor prognosis and represent a challenge in reproductive medicine.Objective: To propose a strategy to improve reproductive prognosis of women older than 38years or young women with low antral follicle count, through the use of testosterone prior to ovarian stimulus.Material and methods: Survey data from the scientific literature in the field of reproductive medicine. Results and conclusions: The use of androgens in stages preceding ovarian stimulation in IVF cycles seems to be great tool for improving oocyte response in oocyte controlled stimulation of patients older than 38 years or with diminished ovarian reserve, improving both quantityand quality of oocytes and increasing rates of pregnancy and live-born.
Subject(s)
Humans , Female , Adult , Middle Aged , Androgens/pharmacology , Aging/physiology , Ovarian Reserve , Fertilization in Vitro , Prognosis , Reproductive Techniques, AssistedABSTRACT
PURPOSE: To determine whether women who had children with Down syndrome (DS) had precocious menopause. METHODS: We selected 104 mothers of children with DS and 121 normal women who had children with no genetic problems. We conducted an interview and compared their mean age at menopause. RESULTS: We did not detect a statistically significant difference in mean age at menopause. When we stratified into women who had conceived when younger or older than 35 years of age, we found a statistically significant difference only for women who had conceived at the age of 35 years or older. We observed three cases of previous unilateral ovarian surgery in the study group and one case in the control group. CONCLUSIONS: We cannot conclude that mothers of children with DS will have precocious menopause. Nevertheless, our findings do not exclude the theory of reduced ovarian reserve as a primordial factor in the genesis of DS.
Subject(s)
Down Syndrome , Menopause, Premature , Adult , Age Factors , Case-Control Studies , Female , Humans , Middle Aged , Parity , Risk FactorsSubject(s)
DNA-Binding Proteins/genetics , Nuclear Proteins/genetics , Transcription Factors/genetics , Turner Syndrome/genetics , Cell Cycle Proteins , Cytogenetic Analysis/methods , DNA/blood , DNA/isolation & purification , DNA/urine , Female , Humans , Karyotyping , Male , Mouth Mucosa/metabolism , Polymerase Chain Reaction , Sex-Determining Region Y Protein , Turner Syndrome/diagnosisABSTRACT
Mitochondria are organelles responsible for oxidative phosphorylation, the main energy source for all eukaryotic cells. In oocytes and embryos, it seems that mitochondria provide sufficient energy for fecundation by supporting spindle formation during meiosis II, and for implantation. Since mitochondria are inherited from mother to child, it is important that oocyte mitochondria should be intact. Older women seem to have more mitochondrial DNA mutations, which can be responsible for poor implantation and aneuploidy, two conditions that occur more often in this group. In the present report we propose a new model to explain why older women have poor implantation rates.
