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Eur J Gastroenterol Hepatol ; 15(10): 1127-30, 2003 Oct.
Article in English | MEDLINE | ID: mdl-14501623

ABSTRACT

Achalasia is a disease of unknown origin in which there is a denervation of the myenteric plexus on the smooth muscle of the lower oesophageal sphincter, causing a cardial stenosis and a loss of efficacy of oesophageal peristalsis. The predominant symptoms are dysphagia for solids and liquids and regurgitation of the retained food. Occasionally, there may be oesophageal haemorrhage as a consequence of oesophagitis and stasis ulcers. An important but uncommon complication is the development of oesophageal cancer, which is typically squamous cell carcinoma. We report an exceptional case of a 77-year-old woman with a long-term achalasia and mega-oesophagus who presented four episodes of upper gastrointestinal bleeding in a 2 month period. The patient underwent surgical resection of the 10 cm of distal oesophagus, performing a partial fundoplication, and the pathological study revealed an oesophageal infiltration by a low-grade non-Hodgkin's lymphoma. After an insidious outcome, she died on the 47th day after admission.


Subject(s)
Esophageal Achalasia/complications , Esophageal Neoplasms/etiology , Leukemia, Lymphocytic, Chronic, B-Cell/etiology , Aged , Esophageal Neoplasms/pathology , Fatal Outcome , Female , Gastrointestinal Hemorrhage/etiology , Humans , Leukemia, Lymphocytic, Chronic, B-Cell/pathology , Recurrence
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