[The problem of the influences of brain cholinergic mechanisms on lipoprotein metabolism in disorders of heat exchange and in emotional stress]. / Problema vliianii kholinergicheskikh mekhanizmov mozga na obmen lipoproteidov pri narusheniiakh teploobmena i pri émotsional'nom stresse.

The contribution of central cholinoreactive systems to the control of plasma lipoprotein metabolism was studied in white rats exposed to cold, overheating and immobilization stress. Possible mechanisms of shifts in fatty-acid composition, as well as high-density lipoprotein cholesterol and total very low and low density lipoproteins, associated with hypothermia, hypertermia and emotional stress under conditions of excitement and blockade of cerebral m- and n-cholinoreceptors, are discussed. Changes in hypothalamic acetylcholin metabolism in stress-exposed animals are demonstrated. It is suggested that central cholinoreactive systems may play an important role in the control of adaptive metabolic reactions involving composite lipids under exposure to low and high environmental temperatures and emotion factors.