ABSTRACT
The aim of this investigation was to determine the role of functional brain state in mechanisms of symptom formation of panic attacks (PA). The clinical and electrophysiological peculiarities of PA connected with their arising in different phases of awakening-sleep cycle were examined in 24 patients. Examination analysis resulted in revelation of some peculiarities in patients with PA of sleep, PA of awakening and PA of sleep and awakening. So the increase of cerebral as well as vegetative activation in patients with PA of sleep and PA of sleep and awakening in relaxed awakening state was observed while in patients with PA of awakening these changes were found during loading probes. The sleep alterations also presented such as diminution of sleep duration, increase of latent periods and decrease of total delta-sleep duration in patients with PA of sleep and with PA of sleep and awakening.