ABSTRACT
PURPOSE: To present the radiologic findings in scleral buckle infections and in the early postoperative period after scleral buckling. METHODS: Retrospective multicenter orbital computed tomography (CT) study of 14 patients and brain magnetic resonance (MR) in one patient with scleral buckle infections, some with the referring diagnosis of endophthalmitis, proliferative vitreoretinopathy, orbital cellulitis, or unilateral headache. The control population consisted of early postoperative prospective CT study of 38 consecutive patients with scleral buckle without clinical infection. RESULTS: Diffuse scleral thickening and preseptal soft tissue swelling were noted in acute scleral buckle infections. Scleral thickening decreased radiologically following prompt antibiotic therapy in five patients with acute infections. Silicone sponge had low attenuation without infection and high attenuation with infection. In chronically infected scleral buckle, the sclera was thickened around the buckle, with scleral melt under the buckle. MR showed increased signal intensity in the preseptal region in one patient with chronic fungal infection. In the controls, two had thickening of the sclera without soft tissue swelling. CONCLUSIONS: CT or MR can assist in the early diagnosis and management of scleral buckle infections.
Subject(s)
Diagnostic Imaging/methods , Endophthalmitis/diagnosis , Eye Infections, Bacterial/diagnosis , Orbital Cellulitis/diagnosis , Prosthesis-Related Infections/diagnosis , Scleral Buckling/adverse effects , Vitreoretinopathy, Proliferative/diagnosis , Adolescent , Adult , Aged , Aged, 80 and over , Diagnosis, Differential , Female , Follow-Up Studies , Humans , Magnetic Resonance Imaging/methods , Male , Middle Aged , Retrospective Studies , Tomography, X-Ray Computed/methodsABSTRACT
AIM: To study the effectiveness of viscocanalostomy in patients with primary congenital glaucoma of the isolated trabecular dysgenesis category and compare it with trabeculotomy ab externo. METHODS: Eight patients with bilateral primary congenital glaucoma were enrolled in the study. After establishing the diagnosis, the more severely affected eye was randomly selected to undergo either trabeculotomy ab externo or viscocanalostomy, whereas the second eye underwent the other surgery 2 weeks after the first. The patients were examined on day 1, week 1, week 4 and thereafter every 4 weeks. Intraocular pressure (IOP) and corneal diameter measurements were obtained at week 1, month 6 and at the last reported follow-up. The paired-sample's Student's t test was applied for statistical analysis. RESULTS: The mean (standard deviation (SD)) follow-up period was 12.5 (1.86) months. Preoperative IOP of eyes undergoing trabeculotomy (34.0 (2.6) mm Hg) and that of eyes undergoing viscocanalostomy (32.3 (4.1) mm Hg) showed no significant difference (p>0.1). A drop in IOP was noted in both groups at week 1, month 6 and at the last follow-up visit (p<0.001). Similarly, a decrease in the postoperative vertical and horizontal corneal diameters was noted in the two study groups. CONCLUSION: Viscocanalostomy proved to be as effective as trabeculotomy ab externo in lowering IOP. Moreover, it is likely to be a good surgical alternative with a higher long-term success rate in eyes with more aggressive disease.
Subject(s)
Filtering Surgery/methods , Glaucoma/congenital , Glaucoma/surgery , Cornea/pathology , Epidemiologic Methods , Female , Filtering Surgery/adverse effects , Glaucoma/physiopathology , Humans , Infant , Infant, Newborn , Intraocular Pressure , Male , Trabeculectomy/adverse effects , Trabeculectomy/methods , Treatment OutcomeABSTRACT
PURPOSE: To prospectively evaluate the intraocular pressure (IOP) lowering ability, retreatment rate, and complications of transcleral Diode laser cyclophotocoagulation using a higher power setting than what is generally recommended. PATIENTS AND METHODS: A total of 36 eyes of thirty six patients with refractory glaucoma, and who fitted our inclusion criteria underwent Diode cyclophotocoagulation. The laser power was set at 2250 mW, with a duration of 2000 ms, and a total number of 28 shots for the first treatment and 20 shots for any consequent one. The patients were followed up for 1 year with the following outcomes being analysed: IOP, visual acuity, change in the number of medications, and complications. RESULTS: The mean IOP decrease was 53% (P < 0.05), and 72.2% of the patients maintained an IOP < or =21 mmHg for the whole duration of the study The number of medications necessary to control the pressure, significantly dropped from 2.8 to 0.89 (P < 0.05), and 25% of the patients needed the treatment to be repeated only once. In all, 33% of the patients improved their visual acuity after the treatment, while 22% worsened, and the rest stayed the same. The most common treatment complications were conjunctival injection and corneal oedema, and these were both transient and reversible. CONCLUSION: The use of the higher power setting of 2250 mW, resulted in a sustained lower IOP, less use of medications, less need for retreatment, relative preservation of visual acuity, and only reversible complications.
Subject(s)
Glaucoma/surgery , Laser Coagulation/methods , Adolescent , Adult , Aged , Aged, 80 and over , Antihypertensive Agents/administration & dosage , Child , Drug Administration Schedule , Female , Follow-Up Studies , Glaucoma/drug therapy , Glaucoma/physiopathology , Humans , Intraocular Pressure , Male , Middle Aged , Prospective Studies , Reoperation , Treatment Outcome , Visual AcuitySubject(s)
Antibodies, Monoclonal/therapeutic use , Antirheumatic Agents/therapeutic use , Behcet Syndrome/drug therapy , Uveitis, Anterior/drug therapy , Uveitis, Posterior/drug therapy , Adult , Behcet Syndrome/complications , Drug Therapy, Combination , Humans , Infliximab , Male , Prednisone/therapeutic use , Treatment Outcome , Uveitis, Anterior/etiology , Uveitis, Posterior/etiology , Vitreous Body/drug effects , Vitreous Body/physiopathologyABSTRACT
PURPOSE: To present a group of patients with surgically induced scleral necrosis characterised by conjunctival retraction. METHODS: Three case reports are presented. RESULTS: The scleral melt responded to conjunctival covering of the scleral defect. CONCLUSION: Surgically induced scleral necrosis associated with conjunctival retraction is best managed by covering the exposed sclera either by stretching the retracted conjunctiva in the early post-operative period or by a conjunctival transplant.
Subject(s)
Cataract Extraction/adverse effects , Sclera/pathology , Aged , Conjunctiva/transplantation , Female , Humans , Male , Middle Aged , NecrosisABSTRACT
PURPOSE: To look at the incidence, symptomatology, course and reversibility of low-dose tamoxifen ocular toxicity. METHODS: Sixty-five women with breast cancer, on tamoxifen oral therapy (20 mg/day), and a totally normal eye examination, were prospectively followed up. A full ophthalmic evaluation was done every 6 months, for a median of 30 months (range 4-79 months). Any sign of toxicity in the cornea, lens, retina or optic nerve was looked for, whether associated with a change in visual acuity or not. RESULTS: Ocular toxicity was documented in 8 patients, giving an incidence of 12%. Seven patients had keratopathy in the form of subepithelial deposits, whorls and linear opacities. Three of these patients had a concurrent symptomatic bilateral pigmentary retinopathy that warranted discontinuation of therapy. One patient developed bilateral optic neuritis that left her with optic nerve pallor and a decrease in vision. The patients who had the toxicity had a significantly higher tamoxifen cumulative dose (p = 0.03), and were longer on treatment (p = 0.04), than the non-affected ones. The keratopathy changes were reversible upon discontinuation of the drug. CONCLUSION: Prompt reporting of symptoms and yearly ophthalmic examinations are mandatory in patients on tamoxifen to detect toxic effects while these are still reversible.
