[Treatment of uncomplicated vertebral compression fractures]. / Lechenie neoslozhnennykh kompressionnykh perelomov pozvonochnika.

According to statistical studies in different countries, the annual incidence of spine and spinal cord injuries is 15-50 cases per 1 million people. In Russia, the incidence of this condition is 5% of the total number of all nonpenetrating traumatic injuries (Neurosurgery: Guidelines for Physicians, ed. by Prof. ON Dreval', 2013). According to the WHO reports, approximately 500,000 people annually experience spine injuries worldwide. Acute spine injuries make up 23.7% of all spinal traumas and include contusions (2.67%), injuries to the capsular ligamentous apparatus (3.88%), fractures and dislocations (7.63%), and muscle injury (9.52%). In males, the risk of experiencing a spine injury is the highest at the age of 20-29 and above 70 years, while in women this risk is the highest at an age of 15-19 and above 60 years. According to the studies, this risk is characterized by an at least 2:1 ratio between adult males and females. OBJECTIVE: To compare the outcomes of surgical (vertebroplasty) and conservative treatment in management of pain syndrome in patients with uncomplicated spine injury. MATERIAL AND METHODS: The study involved 60 patients with stable uncomplicated compression fractures of vertebral bodies in the thoracic and lumbosacral spine. These patients were subdivided into two groups. Group 1 consisted of 30 patients who had undergone unilateral transpedicular percutaneous vertebroplasty; Group 2 involved 30 patients who had undergone a course of conservative treatment. The medical records and the catamnestic follow-up data of patients treated at the Neurosurgery Department of the Research Clinical Center of JSC Russian Railways in 2015-2017 were analyzed for this purpose. RESULTS: No statistically significant differences in sex, age, and level of injury were revealed between the study groups. A comparative analysis of treatment outcomes demonstrated that pain intensity assessed using the VAS scale was significantly reduced after one-year follow-up in both groups as compared to the baseline. A statistically significant decrease in pain intensity in the group of patients who had undergone vertebroplasty was observed as early as one month after the injury. No significant intergroup differences were observed in the long-term follow-up period (3 and 6 months) for this parameter. In five out of 60 patients, examination 12 months after the injury revealed that vertebral body height decreased by up to 10%. No statistically significant correlation with the treatment method was observed. CONCLUSION: Vertebroplasty provides a statistically better pain relief during the first month after spine injury as compared to conservative treatment. For patients, this means earlier activization and quicker return to daily routines and work.

Properties and outcomes of spinal rehabilitation units in four countries.

OBJECTIVE: Compare rehabilitation after spinal cord lesions (SCL) in different countries. DESIGN: Multicenter comparative study. SETTING: Four spinal rehabilitation units, in Denmark, Russia, Lithuania and Israel. SUBJECTS: 199 SCL patients. INTERVENTIONS: Information was collected about unit properties, rehabilitation objectives, American Spinal Injury Association (ASIA) scale and spinal cord independence measure (SCIM) assessments, and patient data. chi (2)-test, t-test, ANOVA and ANCOVA were used for statistical analysis. MAIN OUTCOME MEASURES: Time from lesion onset to admission for rehabilitation (TAR), length of stay in rehabilitation (LOS), SCIM and spinal cord ability realization measurement index (SCI-ARMI) scores, SCIM gain, SCI-ARMI gain and rehabilitation efficiency (RE). RESULTS: Differences were found between the units in rehabilitation objectives, facilities and special equipment for rehabilitation. Staff/bed ratio was 1.7 in Lithuania and Denmark, 1.1 in Israel and 0.9 in Russia. Russian patients were the youngest and had the most severe lesions among participating units. Admission SCIM and SCI-ARMI were the lowest in Israel: 25.1+/-17.2 and 34.3+/-17.3. TAR was highest in Russia (12.4 month) and lowest in Israel (2 weeks; P<0.01). LOS was longest in Denmark (176.9 days; P<0.001). SCIM score at the end of rehabilitation was highest in Denmark (67.3+/-23). SCIM gain and SCI ARMI gain were highest in Israel (36.9+/-18.3 and 38.5+/-19.4, respectively) and lowest in Russia (P<0.001). RE was highest in Lithuania and lowest in Denmark (P<0.001). CONCLUSIONS: In the participating units, SCL rehabilitation outcomes depend on SCL severity and unit-specific properties. A moderately delayed rehabilitation with long LOS achieved high functioning, and early or slightly delayed rehabilitation combined with shorter LOS achieved high functional gain or efficiency.

[The epidural administration of pentamine as a method for stimulating the functions of the small intestine in the early postoperative period]. / Epidural'noe vvedenie pentamina kak metod stimuliatsii funktsii tonkoi kishki v rannem posleoperatsionnom periode.

A technique of prolonged sympathetic ganglion blockage with an epidurally applied ganglioblocker pentamine has been suggested. With the help of manometry, using an open catheter and electromyography methods, the effect of the above technique on the recovery of the damaged small intestinal functions in the early postoperative period has been studied in comparison with prolonged epidural blockade with trimecaine in patients after gastric surgery. The effect of epidurally administered drugs on central hemodynamics has been studied. The technique suggested is effective for the recovery of the damaged small intestinal functions and has a number of advantages over conventional prolonged epidural blockade: less pronounced effect on central hemodynamics, the absence of blocking effect on afferent pulsation. All these makes it a technique of choice in patients with severe homeostasis disturbances and low central hemodynamic indexes.