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1.
Heliyon ; 10(1): e23560, 2024 Jan 15.
Article in English | MEDLINE | ID: mdl-38173480

ABSTRACT

Background: Pregnancy, childbirth and the postpartum period represent a unique experience in a woman's life that significantly changes their life. Methods: The aim of the study is to analyse risk factors of postpartum depression and posttraumatic stress disorder symptoms after birth in a sample of women in Slovakia. Data from the INTERSECT project were collected, including 437 postpartum women (mean age 30.5 ± 4.8). Posttraumatic stress disorder was (PTSD) measured through the City BiTS questionnaire, postpartum depression (PPD) symptoms were detected using the Edinburgh Postnatal Depression Scale (EPDS) and birth satisfaction was measured by the Birth Satisfaction Scale- Revised (BSS-R). Results: An increased risk for the development of PPD (the EPDS score >12.5) was found in 11.4 % of respondents, PTSD after birth was identified among 2.8 % of respondents. In the linear regression models, birth satisfaction (95%CI: 0,56; -0,19), subjective perception of birth (95%CI: 0,82; 1,63), previous trauma (95%CI: 0,27; 3,74), respect during birth (95%CI: 5,08; -0,45), and health complications of both mother (95%CI: 0,12; 2,81) and child (95%CI: 1,53; 1,84) were found significantly associated with the posttraumatic stress symptoms after birth (total explained variance 37 %). Subjective perception of birth as traumatic (95%CI: 0,82; 1,63), previous trauma in the anamnesis (95%CI: 0,27; 3,74) and respect during birth (95%CI: 5,08; -0,45) were significantly associated with the depression symptoms (total explained variance 15 %). Conclusion: Subjective perception of birth, birth satisfaction, previous trauma in anamnesis as well as lack of respect during birth were found as crucial risk factors for both PPD and postpartum PTSD.

2.
Article in English | MEDLINE | ID: mdl-36767994

ABSTRACT

BACKGROUND: The aim of the study is to analyse the risk of postpartum depression using dimensions of perceived support (information, emotional, and physical), antenatal education (satisfaction and attitude), and attitude toward pregnancy (wanted or unwanted). METHODS: A cross-sectional study was carried out among 584 postpartum women in two university birth centres in Slovakia. The Edinburgh Postnatal Depression Scale (EPDS) score was used. Descriptive statistics and analysis of variance, as well as logistic regression, were employed in the study. Found associations were adjusted for education level, type of birth, psychiatric history, and age. RESULTS: As many as 95.1% of women reported their pregnancy as being wanted. Antenatal education, particularly satisfaction with it, showed a negative association with the EPDS score level. No significant differences in depression levels were found considering attitude toward pregnancy and perceived support. CONCLUSIONS: The study pointed out the significance of antenatal education to lower the risk of the postpartum depression. One of the important criteria of effective education is a woman's subjective satisfaction with it.


Subject(s)
Depression, Postpartum , Female , Pregnancy , Humans , Depression, Postpartum/epidemiology , Depression, Postpartum/psychology , Cross-Sectional Studies , Parturition , Postpartum Period , Slovakia , Risk Factors , Psychiatric Status Rating Scales , Depression/psychology
3.
Cent Eur J Public Health ; 30(2): 79-85, 2022 Jun.
Article in English | MEDLINE | ID: mdl-35876595

ABSTRACT

OBJECTIVES: The aim of this study is to analyse Global Youth Tobacco Survey (GYTS) data on a prevalence of tobacco use, indicators of tobacco control and pro-tobacco activities in Czechia and Slovakia between 2002 and 2016. METHODS: GYTS is a school-based survey of students aged 13-15 years carried out in Czechia and Slovakia in 2002/2003, 2007, 2011 and 2016. Standardized uniform questionnaires provided representative data. RESULTS: Between 2002 and 2016 the current cigarette smoking declined both in Czechia and Slovakia (from 34.6% and 26.4% to 15.2% and 17.1%, respectively). Indicators of tobacco control activities either did not change (access to buy cigarettes by minors) or decreased (school-based and mass media interventions). Indicators of pro-tobacco activities declined (being ever offered by a free tobacco product and having something with a tobacco product brand logo on it). CONCLUSIONS: Tobacco use is on decline and the situation becomes similar to the most of European countries. Preventive activities are only partially responsible for the process. Rather effect of global trends accelerated by widespread use of social media can play a role.


Subject(s)
Nicotiana , Tobacco Products , Adolescent , Czech Republic/epidemiology , Humans , Prevalence , Slovakia/epidemiology , Surveys and Questionnaires , Tobacco Use/epidemiology
4.
Int J Nurs Educ Scholarsh ; 19(1)2022 Jul 12.
Article in English | MEDLINE | ID: mdl-35822716

ABSTRACT

BACKGROUND: The objective is to introduce the creating a set of virtual patients (VPs) to support distance midwifery education as well as the impact of distance education by means of VPs on knowledge, skills, motivation, clinical practice, and student satisfaction. METHODS: VPs were created using OpenLabyrinth (OL). The impact of the distance education was assessed using a feedback questionnaire. RESULTS: When creating our own VPs, the design and development phase can be considered the most difficult. On a scale of 1 (agree) to 4 (disagree), the student feedback rates were mostly positive (1.04-2.13). A high degree of agreement was associated with the acquisition of theoretical knowledge (1.15-1.28) and skills (1.43). CONCLUSIONS: The creation of our own VPs is challenging for teachers due to its unconventional character. The students expressed great satisfaction with distance learning, but lacked face-to-face contact with the patient.


Subject(s)
Education, Distance , Midwifery , Female , Humans , Midwifery/education , Pregnancy , Surveys and Questionnaires
5.
Article in English | MEDLINE | ID: mdl-34639758

ABSTRACT

Negative experiences with childbirth might have a negative impact on a woman's overall health, including a higher risk of postpartum depression. The aim of the study was to examine the association between birth satisfaction and the risk of postpartum depression (PPD). A 30-item version of the Birth Satisfaction Scale (BSS) and the Edinburgh Postnatal Depression Scale (EPDS) were used, as well as the Perceived Stress Scale (PSS). The study included 584 women (mean age 30.6 ± 4.9), 2 to 4 days postpartum. In the regression model, the negative effect of birth satisfaction on the risk of postpartum depression was shown: a lower level of satisfaction with childbirth was a significant predictor of a higher risk of PPD (ß = -0.18, 95% CI = -0.08; -0.03). The regression model was controlled for the effect of the sociodemographic factors (such as education or marital status) and clinical variables (such as parity, type of delivery, psychiatric history, levels of prenatal stress). Levels of prenatal stress (ß = 0.43, 95% CI = 0.27; 0.39), psychiatric history (ß = 0.08, 95% CI = 0.01; 3.09), parity (ß = -0.12, 95% CI = -1.82; -0.32) and type of delivery (ß = 0.11, 95% CI = 0.20; 1.94) were also significantly associated with the levels of postnatal depression. The current study confirmed the association between the level of birth satisfaction and the risk of developing PPD, i.e., a lower satisfaction with childbirth may increase the risk of developing PPD.


Subject(s)
Depression, Postpartum , Adult , Depression, Postpartum/epidemiology , Female , Humans , Parturition , Personal Satisfaction , Postpartum Period , Pregnancy , Risk Factors
6.
Article in English | MEDLINE | ID: mdl-34200855

ABSTRACT

BACKGROUND: Postpartum depression has a negative impact on quality of life. The aim of this study was to examine the factor structure and psychometric properties of the Slovak version of the Edinburgh Postnatal Depression Scale (EPDS). METHODS: A paper and pencil version of the 10-item EPDS questionnaire was administered personally to 577 women at baseline during their stay in hospital on the second to fourth day postpartum (age, 30.6 ± 4.9 years; 73.5% vaginal births vs. 26.5% operative births; 59.4% primiparas). A total of 198 women participated in the online follow-up 6-8 weeks postpartum (questionnaire sent via e-mail). RESULTS: The Slovak version of the EPDS had Cronbach's coefficients of 0.84 and 0.88 at baseline (T1) and follow-up, respectively. The three-dimensional model of the scale offered good fit for both the baseline (χ2(df = 28) = 1339.38, p < 0.001; CFI = 0.99, RMSEA = 0.02, and TLI = 0.99) and follow-up (χ2(df = 45) = 908.06, p < 0.001, CFI = 0.93, RMSEA = 0.09, and TL = 0.90). A risk of major depression (EPDS score ≥ 13) was identified in 6.1% in T1 and 11.6% in the follow-up. Elevated levels of depression symptoms (EPDS score ≥ 10) were identified in 16.7% and 22.7% of the respondents at baseline and follow-up, respectively. CONCLUSIONS: The Slovak translation of the EPDS showed good consistency, convergent validity, and model characteristics. The routine use of EPDS can contribute to improving the quality of postnatal health care.


Subject(s)
Depression, Postpartum , Quality of Life , Adult , Depression, Postpartum/diagnosis , Depression, Postpartum/epidemiology , Female , Humans , Postpartum Period , Psychiatric Status Rating Scales , Psychometrics , Reproducibility of Results , Slovakia/epidemiology
7.
Article in English | MEDLINE | ID: mdl-34064569

ABSTRACT

BACKGROUND: The article analyzes selected indicators of alcohol use (weekly use, drunkenness within last month) and the ability of adolescents to buy alcohol in Slovakia between 2010 and 2018. METHODS: Health Behavior in School-Aged Children (HBSC) is a cross-sectional questionnaire study. A standardized uniform questionnaire was used to create a representative sample of 15-year-old adolescents. Two surveys carried out in Slovakia in 2010 (n = 1568) and 2018 (n = 1298) were analyzed. RESULTS: Weekly alcohol use and drunkenness declined only in boys, not in girls. Affordability of alcohol (not being prevented from buying it) declined among weekly drinking boys (from 60.4 to 34.1%) but remained almost unchanged in girls from a higher socioeconomic group compared to those from a lower one (57.9% vs. 30.6% in 2018). CONCLUSIONS: Affordability of alcohol in boys decreased with a decline in alcohol use, corresponding with implemented legislative measures. However, it remained unchanged in girls from a higher socioeconomic group.


Subject(s)
Adolescent Behavior , Alcohol Drinking , Adolescent , Alcohol Drinking/epidemiology , Child , Costs and Cost Analysis , Cross-Sectional Studies , Female , Humans , Male , Policy , Slovakia/epidemiology , Surveys and Questionnaires
8.
Midwifery ; 79: 102550, 2019 Dec.
Article in English | MEDLINE | ID: mdl-31610363

ABSTRACT

OBJECTIVE: This study is focused on assessing psychometric properties of the Slovak version of the 30-item Birth Satisfaction Scale (BSS) and revised 10-item BSS-R. STUDY DESIGN: Quantitative cross-sectional study design was used, with the primary goal of examining factor structure, internal consistency, and both divergent and known-groups validity of the Slovak version of BSS and BSS-R. SETTING: Four public hospital sites in central Slovakia PARTICIPANTS: A 30-item BSS questionnaire was administered to 506 women 2-4 days after birth (mean age 29.9 years, SD = 5.1). RESULTS: The mean BSS score was 112 (SD 13.6, score range 30-150), and BSS-R 27.3 (SD 5.4, score range 0-40). Significantly higher birth satisfaction was found among women after physiological birth, multiparas, women with supporting person at birth, with pain relief, and with university education. Both Slovak version of BSS and BSS-R have been shown to have good reliability, as well as good divergent and known-group validity. The results of confirmatory factor revealed that three-factor model of the BSS-R offers a good fit to the Slovak data (χ2, df32) = 79.40, p < 0.001, CFI = 0.96 and RMSEA = 0.05). KEY CONCLUSIONS: The Slovak version of the 10-item BSS-R has been found to have excellent psychometric properties and can be used as a valid outcome measure of birth satisfaction in Slovak hospital settings.


Subject(s)
Delivery, Obstetric/psychology , Personal Satisfaction , Prenatal Care , Psychometrics , Adolescent , Adult , Cross-Sectional Studies , Female , Humans , Pregnancy , Reproducibility of Results , Slovakia , Surveys and Questionnaires , Translations , Young Adult
9.
Perfusion ; 34(5): 433-436, 2019 07.
Article in English | MEDLINE | ID: mdl-30632944

ABSTRACT

INTRODUCTION: Sufentanil is a potent analgesic drug used for pain management. A few studies describe the pharmacokinetics of sufentanil in neonates; however, no pharmacokinetic data about sufentanil during extracorporeal membrane oxygenation have been published yet. CASE REPORT: A 1-day-old neonate with moderate hypoxic-ischemic encephalopathy received veno-arterial extracorporeal membrane oxygenation support for refractory respiratory and circulatory failure. Sufentanil plasma concentrations were determined during both extracorporeal membrane oxygenation (n = 14) and non-extracorporeal membrane oxygenation (n = 17) period. Based on these measurements, individual sufentanil pharmacokinetic parameters were calculated. DISCUSSION: We observed increased sufentanil volume of distribution (11.6 vs 5.6 L/kg) and decreased sufentanil clearance (0.535 vs 0.746 L/h/kg) in extracorporeal membrane oxygenation period. The increment of volume of distribution was attributed to ECMO influence, while difference in clearance was probably due to drug interaction. CONCLUSIONS: This is the first description of sufentanil pharmacokinetics in neonate treated with extracorporeal membrane oxygenation. We observed considerably larger volume of distribution during extracorporeal membrane oxygenation period in comparison with non-extracorporeal membrane oxygenation period.


Subject(s)
Analgesics, Opioid/pharmacokinetics , Extracorporeal Membrane Oxygenation/adverse effects , Sufentanil/pharmacokinetics , Analgesics, Opioid/therapeutic use , Extracorporeal Membrane Oxygenation/methods , Humans , Infant, Newborn , Sufentanil/therapeutic use
10.
Midwifery ; 62: 1-5, 2018 Jul.
Article in English | MEDLINE | ID: mdl-29614387

ABSTRACT

OBJECTIVE: The objective of the study was to create several new, original virtual patients (VPs) in the Slovak language, especially for educational purposes in midwifery. SETTING: Virtual patients have been created for the needs of university midwifery education in Slovakia. MODEL: The creation of the six virtual patients basically consisted of three fixed stages: preparation, design and development, implementation into the virtual environment. We used the Open Labyrinth (OL) virtual environment, an open-source system for creating VPs. The VPs include six various scenarios of the most common problems seen in midwifery practice: preterm birth, perinatal loss, gestational diabetes, ineffective breastfeeding, postpartum bleeding and sudden home birth. FINDINGS: Currently, six original virtual patients are used in university midwifery education in Slovakia. We use them for contact teaching as well as self-study of students. They present the first VPs in Slovakia and the Czech Republic created in academic settings in these countries. CONCLUSIONS: The future perspective of a virtual patient as an interactive process between the student and the medium is that it can deepen and improve learning outcomes, solve specific midwifery issues, and reduce mistakes in the clinical environment.


Subject(s)
Curriculum/trends , Midwifery/education , Patient Simulation , Education, Nursing/methods , Educational Measurement/methods , Humans , Slovakia , Software Design
11.
Midwifery ; 59: 1-3, 2018 Apr.
Article in English | MEDLINE | ID: mdl-29331775

ABSTRACT

The simulation training in midwifery has a long tradition. It is aimed at acquiring basic and advanced practical skills such as performing a certain number of births, episiotomy and subsequent suture, assisting during breech birth etc. Midwifery education is currently based on the requirements of the Directives of the European Union exactly specifying number of performed practical procedures and approaches (World Health Organisation (WHO) Europe, 2009). The aim of this paper is to draw attention to the experience with the simulation training from the teacher's point of view in the study program Midwifery in Slovakia. The authors describe the locations for training of midwifery skills, training of basic and advanced midwifery skills using simulation, the types of simulators available and used and training approaches. They outline the advantages and disadvantages of using obstetric simulators based on their own experience.


Subject(s)
Faculty, Nursing/psychology , Midwifery/education , Simulation Training/standards , Adult , Curriculum/trends , Education, Nursing, Baccalaureate/methods , Education, Nursing, Baccalaureate/standards , Female , Humans , Pregnancy , Slovakia
12.
Cent Eur J Public Health ; 25(3): 216-221, 2017 Sep.
Article in English | MEDLINE | ID: mdl-29022681

ABSTRACT

OBJECTIVES: The aim of the study was to examine body-image dissatisfaction in adolescents aged 13-15 years reporting to be on a diet and to assess gender and age differences in weight-reduction behaviour in Slovak adolescents. METHODS: Data on a representative sample of 2,765 adolescents (mean age 14.37 years) from the Slovak part of Health Behaviour in School Aged Children Study carried out in 2014 were analysed. Self-reported body-image dissatisfaction and engagement in weight-reduction behaviour of 13 to 15-year-old adolescents was assessed using multiple logistic regression models. RESULTS: More that 20% of boys and 35% of girls perceived themselves to be too fat. Girls reported being on a diet more frequently than boys (28.8% vs. 14.9%). The most frequent weight-reduction behaviours were drinking more water (67.7%), eating more fruits and vegetables (67.1%), and consuming fewer sweets (60.5%) and soft drinks (51.7%). Girls prevailed above boys in the use of these dietary methods. Age differences were not apparent, except for smoking, believed to help in weight reduction and used upmost by 15-year-olds (8.9%) followed by 14 and 13-year-olds, 6.0% and 4.1%, respectively. CONCLUSIONS: Body-image dissatisfaction and weight-control behaviour are issues particularly in girls, however, they did not necessarily correspond with actual obesity. The most commonly used weight-reduction behaviours are in the same way important aspects of a healthy lifestyle. There is room to improve obesity control, particularly within primary health care.


Subject(s)
Adolescent Behavior/psychology , Body Image/psychology , Diet, Reducing/psychology , Diet, Reducing/statistics & numerical data , Personal Satisfaction , Adolescent , Feeding Behavior/psychology , Female , Humans , Male , Sex Factors , Slovakia
13.
Midwifery ; 33: 43-5, 2016 Feb.
Article in English | MEDLINE | ID: mdl-26632483

ABSTRACT

Problems in midwifery in many Central-Eastern European countries are very similar; it is possible to speak about the evolving Central-Eastern model of midwifery care. The educational models of this region have a relatively strong theoretical part; however, there is an insufficient practical dimension. Theoretical part of midwifery education in the universities is relatively autonomous and is slowly changing the professional identity of graduates.


Subject(s)
Curriculum , Midwifery/education , Models, Educational , Nurse Midwives/education , Europe, Eastern , European Union , Maternal Health Services , Professional Role , Surveys and Questionnaires
14.
Med Sci Monit ; 17(2): CR97-103, 2011 Feb.
Article in English | MEDLINE | ID: mdl-21278695

ABSTRACT

BACKGROUND: The number of incoming expectant women who have previously experienced cesarean section has increased. This work sought to find the frequency and connections between vaginal deliveries, cesarean sections, and iterative cesarean sections from 2004 to 2008. MATERIAL/METHODS: In all, 828 women with previous cesarean sections were included. From this group, 8282 vaginal deliveries were performed. During these years, 828 women had a history of the cesarean section; in these women, iterative cesarean sections were indicated. To evaluate knowledge of educational material designed for women being prepared for the iterative delivery, we used information compiled on experience from 2002 to 2003; the same approach was used to evaluate the nursing process on interventions and diagnoses of cesarean sections. RESULTS: From 2004 to 2008, 11 279 deliveries were performed in the Perinatological Center in Ceské Budejovice; this was significant (P<.001). The same result was obtained in the relation for the total number of deliveries and those performed by the iterative cesarean section. The number of iterative cesarean sections in women who had already experienced the cesarean section (828) and delivered by cesarean section again is 620. Other data were not significant. Only 2 to 3 pregnancies next to the first cesarean section were statistically significant in 2004 and 2005. CONCLUSIONS: If a trial of labor after cesarean does not proceed to vaginal birth, the woman will need support and encouragement to express feelings about another cesarean birth.


Subject(s)
Cesarean Section/statistics & numerical data , Parturition , Adult , Female , Gestational Age , Health Knowledge, Attitudes, Practice , Humans , Midwifery , Patient Admission , Pregnancy , Sterilization, Reproductive
15.
Int J Public Health ; 54(6): 439-45, 2009.
Article in English | MEDLINE | ID: mdl-19680601

ABSTRACT

OBJECTIVES: To present Global Youth Tobacco Survey (GYTS) data on the prevalence of cigarette smoking and selected social factors among students aged 13-15 years in 25 European countries. METHODS: The GYTS is a school-based survey of students aged 13-15 years. The GYTS was conducted in 25 European countries (2002-2005) and produced representative data for each country. RESULTS: In 25 European countries studied, 22% of boys and 18% of girls smoked cigarettes. In 17 of 25 countries, current cigarette smoking did not differ between boys and girls. Exposure to secondhand smoke is very high throughout the 25 countries. Exposure to pro-tobacco indirect advertising (having tobacco company logos on promotional items and being given free cigarettes) is frequent throughout the countries. CONCLUSIONS: Intensified efforts to lessen harm caused by tobacco use among youth in 25 European countries included in this study are urgently needed. These countries need to develop and implement comprehensive tobacco control programs including public education campaigns, cessation programs, enforcement of existing measures, and related policy efforts. The WHO FCTC provides a useful framework for implementing such a comprehensive approach.


Subject(s)
Smoking/epidemiology , Social Environment , Adolescent , Advertising , Europe/epidemiology , Female , Health Surveys , Humans , Male , Tobacco Smoke Pollution
16.
Int J Public Health ; 52(1): 62-6, 2007.
Article in English | MEDLINE | ID: mdl-17966821

ABSTRACT

OBJECTIVES: To present data on Environmental Tobacco Smoke (ETS), Global Youth Tobacco Survey (GYTS), Czech Republic, Hungary, Poland and Slovakia. METHODS: A questionnaire survey of a representative sample of 16 918 schoolchildren aged 13-15 years (2002-2003). RESULTS: Exposure to ETS was reported more frequently in public places than in homes and more frequently from current smokers (CS) than from never smokers (NS). ETS in homes was lower in Czech (57.6% in CS, 24.7% in NS) than in other countries (the highest in Poland: 93.0% in CS, 80.9% in NS). ETS in public places was highest in Hungary (96.9% in CS, 89.2% in NS), lowest in Czech (90.1% in CS, 57.3% in NS). Most students considered ETS as harmful and presented positive attitudes towards smoking ban. DISCUSSION: ETS in studied countries, save the Czech Republic, exceeded the global prevalence, while the situation is better than in numerous other Eastern European countries.


Subject(s)
Cross-Cultural Comparison , Tobacco Smoke Pollution/statistics & numerical data , Adolescent , Attitude to Health , Cross-Sectional Studies , Czech Republic , Female , Health Surveys , Humans , Hungary , Male , Poland , Slovakia , Smoking/epidemiology , Social Environment , Tobacco Smoke Pollution/adverse effects
17.
Cent Eur J Public Health ; 15(1): 29-32, 2007 03.
Article in English | MEDLINE | ID: mdl-17491556

ABSTRACT

OBJECTIVE: The article analyses changes in tobacco use in medical students in Slovakia in 1995, 1999 and 2004. METHODS: Questionnaire survey in 448 students of the Jessenius Faculty of Medicine, Comenius University in Martin, Slovakia, was carried out in October and November 2004. Data were compared with similar surveys carried out in 1995 and 1999. RESULTS: Prevalence of daily smoking in men increased from 11.1 in 1995 to 21.8% in 2004. In women, within 1995-2004, daily smoking increased from 5.2% to 12.3%, occasional smoking from 11.6% to 19.8%. Also proportion of women initiating smoking during their university study increased. In both genders the proportion of never smokers dramatically dropped between 1995 and 1999 (in men from 43.2% to 23.2%; in women from 61.9 to 18.2). CONCLUSION: Upward trend in tobacco use, particularly in women, is a reason for concern. In medical faculties, principles of prevention should be more emphasized and the students motivated for healthy life-style and to fulfill their future role in public health. The situation noted among medical students indicates that a community in Slovakia is still not satisfactory inclined towards non-smoking and a dramatic decrease of tobacco use can hardly be expected either in the near future.


Subject(s)
Smoking/epidemiology , Students, Medical/statistics & numerical data , Adolescent , Adult , Female , Humans , Male , Prevalence , Sex Distribution , Slovakia/epidemiology , Smoking/trends , Surveys and Questionnaires
18.
Expert Opin Pharmacother ; 5(3): 487-91, 2004 Mar.
Article in English | MEDLINE | ID: mdl-15013917

ABSTRACT

Smoking cessation represents a very difficult task for the smoker, often requiring medical assistance. The introduction of smoking cessation drugs has been crucial to this process. Currently, there are two standardly used treatments: nicotine replacement therapy (NRT) and the antidepressant bupropion. Soon after their introduction, NRTs were sold over-the-counter (OTC), as oppose to on prescription, although in most countries, bupropion remains available only on prescription. Both prescribed and OTC NRTs have similar efficacy (i.e., their use approximately doubles the cessation rate among users and their use has shown a high level of economic rewarding). The most important advantage of OTC NRT is availability, as some patients may not be comfortable with the use of prescribed drugs. The introduction of OTC NRT has led to a substantial rise in their use, increasing the proportion of ex-smokers in the population. However, there are a lack of published, cost-benefit analysis data comparing prescription with OTC NRT. Considering the different economic, social and cultural conditions within particular countries, it is difficult to formulate a common optimal economic model for the distribution of NRT. Authentic studies and trials in this field in order to develop the appropriate policies in each particular country, are clearly required.


Subject(s)
Drug Prescriptions/economics , Nicotine/economics , Nonprescription Drugs/economics , Smoking Cessation/economics , Bupropion/economics , Bupropion/therapeutic use , Clinical Trials as Topic , Dopamine Uptake Inhibitors/economics , Dopamine Uptake Inhibitors/therapeutic use , Dosage Forms , Humans , Nicotine/therapeutic use , Nonprescription Drugs/therapeutic use
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