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1.
Actas dermo-sifiliogr. (Ed. impr.) ; 114(1): 1-8, jan. 2023. tab
Article in English | IBECS | ID: ibc-214464

ABSTRACT

Background and objectives Hidradenitis suppurativa is a chronic and painful condition with negative impact on daily activity. Little information on the impact of disease-specific factors on educational level and occupational status in hidradenitis suppurativa patients has been reported. We sought to identify how disease-specific factors could influence occupational status and educational level in patients with hidradenitis suppurativa. Methods Cross-sectional study of patients with hidradenitis suppurativa seen between September 2017 and September 2018. Disease-specific variables were analyzed to find associations in patients with different educational levels and occupational status. Results Ninety-eight patients were included. Patients with non-university studies had more frequently ≥ 3 affected areas (22.5% [16/73] vs 4.8% [1/22], p = 0.049), a higher number of painful days (8.5 [SD 8.8] vs 4.6 [SD 4.8], p = 0.048) and a higher score on the VAS scale (6.7 [SD 2.8] vs 5.0 [3.3], p = 0.031). Patients from the inactive group had a significantly increased number of painful days (11.2 [SD 10.4] vs 5.7 [SD 6.2], p = 0.004). This group had a greater number of patients with a history of depression (61.3% [19/31] vs 27.4% [17/62], p = 0.002) and a higher mean BMI (32.3 [9.1] vs 28.4 [6.4], p = 0.016). Late disease onset was significantly associated with being “inactive” (26.7% [8/31] vs 6.5% [4/62], p = 0.026). No significant differences between severity scales of hidradenitis suppurativa and educational level or occupational status were found. Limitations: cross-sectional and single center study. Conclusions Pain, ≥3 affected areas, history of depression, higher mean BMI, and late onset of hidradenitis suppurativa, are associated with low education level and inactive occupational status (AU)


Antecedentes y objetivos La hidrosadenitis supurativa es una condición crónica y dolorosa, con impacto negativo en la actividad diaria. Se ha reportado poca información sobre el impacto que tienen los factores específicos de la enfermedad en el nivel educativo y el estatus ocupacional de los pacientes con esta situación. Nuestro objetivo fue identificar el modo en que dichos factores específicos de la enfermedad podrían influir en el nivel educativo y el estatus ocupacional de los pacientes con hidrosadenitis supurativa. Métodos Estudio transversal de pacientes con hidrosadenitis supurativa examinados entre septiembre de 2017 y septiembre de 2018. Se analizaron las variables específicas de la enfermedad para encontrar una asociación en los pacientes con diferentes niveles educativos y estatus ocupacionales. Resultados Se incluyó a 98 pacientes. Aquellos con estudios no universitarios tenían afectadas más frecuentemente ≥ 3 zonas (22,5% [16/73] vs. 4,8% [1/22], p = 0,049), pasaban un elevado número de días con dolor (8,5 [DE 8,8] vs. 4,6 [DE 4,8], p = 0,048) y su puntuación en la escala EVA era alta (6,7 [DE 2,8] vs. 5 [3,3], p = 0,031). Los pacientes pertenecientes al grupo inactivo tenían un número considerablemente incrementado de días con dolor (11,2 [DE 10,4] vs. 5,7 [DE 6,2], p = 0,004). En este grupo había un mayor número de pacientes con historia de depresión (61,3% [19/31] vs. 27,4% [17/62], p = 0,002) y un mayor IMC medio (32,3 [9,1] vs. 28,4 [6,4], p = 0,016). El inicio tardío de la enfermedad se asoció significativamente a la situación de «inactivo» (26,7% [8/31] vs. 6,5% [4/62], p = 0,026). No se encontraron diferencias significativas entre las escalas de gravedad de la hidrosadenitis supurativa y el nivel educativo y el estatus ocupacional. Limitaciones: estudio transversal y unicéntrico (AU)


Subject(s)
Humans , Male , Female , Adolescent , Young Adult , Adult , Middle Aged , Hidradenitis Suppurativa/complications , Pain/etiology , Occupations/statistics & numerical data , Educational Status , Cross-Sectional Studies , Quality of Life , Socioeconomic Factors , Surveys and Questionnaires
2.
Actas dermo-sifiliogr. (Ed. impr.) ; 114(1): T1-T8, jan. 2023. tab
Article in Spanish | IBECS | ID: ibc-214465

ABSTRACT

Antecedentes y objetivos La hidrosadenitis supurativa es una condición crónica y dolorosa, con impacto negativo en la actividad diaria. Se ha reportado poca información sobre el impacto que tienen los factores específicos de la enfermedad en el nivel educativo y el estatus ocupacional de los pacientes con esta situación. Nuestro objetivo fue identificar el modo en que dichos factores específicos de la enfermedad podrían influir en el nivel educativo y el estatus ocupacional de los pacientes con hidrosadenitis supurativa. Métodos Estudio transversal de pacientes con hidrosadenitis supurativa examinados entre septiembre de 2017 y septiembre de 2018. Se analizaron las variables específicas de la enfermedad para encontrar una asociación en los pacientes con diferentes niveles educativos y estatus ocupacionales. Resultados Se incluyó a 98 pacientes. Aquellos con estudios no universitarios tenían afectadas más frecuentemente ≥ 3 zonas (22,5% [16/73] vs. 4,8% [1/22], p = 0,049), pasaban un elevado número de días con dolor (8,5 [DE 8,8] vs. 4,6 [DE 4,8], p = 0,048) y su puntuación en la escala EVA era alta (6,7 [DE 2,8] vs. 5 [3,3], p = 0,031). Los pacientes pertenecientes al grupo inactivo tenían un número considerablemente incrementado de días con dolor (11,2 [DE 10,4] vs. 5,7 [DE 6,2], p = 0,004). En este grupo había un mayor número de pacientes con historia de depresión (61,3% [19/31] vs. 27,4% [17/62], p = 0,002) y un mayor IMC medio (32,3 [9,1] vs. 28,4 [6,4], p = 0,016). El inicio tardío de la enfermedad se asoció significativamente a la situación de «inactivo» (26,7% [8/31] vs. 6,5% [4/62], p = 0,026). No se encontraron diferencias significativas entre las escalas de gravedad de la hidrosadenitis supurativa y el nivel educativo y el estatus ocupacional. Limitaciones: estudio transversal y unicéntrico (AU)


Background and objectives Hidradenitis suppurativa is a chronic and painful condition with negative impact on daily activity. Little information on the impact of disease-specific factors on educational level and occupational status in hidradenitis suppurativa patients has been reported. We sought to identify how disease-specific factors could influence occupational status and educational level in patients with hidradenitis suppurativa. Methods Cross-sectional study of patients with hidradenitis suppurativa seen between September 2017 and September 2018. Disease-specific variables were analyzed to find associations in patients with different educational levels and occupational status. Results Ninety-eight patients were included. Patients with non-university studies had more frequently ≥ 3 affected areas (22.5% [16/73] vs 4.8% [1/22], p = 0.049), a higher number of painful days (8.5 [SD 8.8] vs 4.6 [SD 4.8], p = 0.048) and a higher score on the VAS scale (6.7 [SD 2.8] vs 5.0 [3.3], p = 0.031). Patients from the inactive group had a significantly increased number of painful days (11.2 [SD 10.4] vs 5.7 [SD 6.2], p = 0.004). This group had a greater number of patients with a history of depression (61.3% [19/31] vs 27.4% [17/62], p = 0.002) and a higher mean BMI (32.3 [9.1] vs 28.4 [6.4], p = 0.016). Late disease onset was significantly associated with being “inactive” (26.7% [8/31] vs 6.5% [4/62], p = 0.026). No significant differences between severity scales of hidradenitis suppurativa and educational level or occupational status were found. Limitations: cross-sectional and single center study. Conclusions Pain, ≥3 affected areas, history of depression, higher mean BMI, and late onset of hidradenitis suppurativa, are associated with low education level and inactive occupational status (AU)


Subject(s)
Humans , Male , Female , Adolescent , Young Adult , Adult , Middle Aged , Hidradenitis Suppurativa/complications , Pain/etiology , Occupations/statistics & numerical data , Educational Status , Socioeconomic Factors , Surveys and Questionnaires , Cross-Sectional Studies , Quality of Life
3.
Actas Dermosifiliogr ; 114(1): T1-T8, 2023 Jan.
Article in English, Spanish | MEDLINE | ID: mdl-36503621

ABSTRACT

BACKGROUND AND OBJECTIVES: Hidradenitis suppurativa (HS) is a chronic and painful condition with negative impact on daily activity. Little information on the impact of disease-specific factors on educational level and occupational status in hidradenitis suppurativa patients has been reported. We sought to identify how disease-specific factors could influence occupational status and educational level in patients with HS. METHODS: Cross-sectional study of patients with HS seen between September 2017 and September 2018. Disease-specific variables were analyzed to find associations in patients with different educational levels and occupational status. RESULTS: Ninety-eight patients were included. Patients with non-university studies had more frequently ≥ 3 affected areas (22.5% [16/73] vs. 4.8% [1/22], p = 0.049), a higher number of painful days (8.5 [SD 8.8] vs. 4.6 [SD 4.8], p = 0.048) and a higher score on the VAS scale (6.7 [SD 2.8] vs. 5.0 [3.3], p = 0.031). Patients from the inactive group had a significantly increased number of painful days (11.2 [SD 10.4] vs. 5.7 [SD 6.2], p = 0.004). This group had a greater number of patients with a history of depression (61.3% [19/31] vs. 27.4% [17/62], p = 0.002) and a higher mean BMI (32.3 [9.1] vs. 28.4 [6.4], p = 0.016). Late disease onset was significantly associated with being «inactive¼ (26.7% [8/31] vs. 6.5% [4/62], p = 0.026). No significant differences between severity scales of HS and educational level or occupational status were found. LIMITATIONS: cross-sectional and single center study. CONCLUSIONS: Pain, ≥ 3 affected areas, history of depression, higher mean BMI, and late onset of HS, are associated with low education level and inactive occupational status.


Subject(s)
Hidradenitis Suppurativa , Humans , Cross-Sectional Studies , Hidradenitis Suppurativa/complications , Hidradenitis Suppurativa/epidemiology , Pain/epidemiology , Pain/etiology , Educational Status , Employment , Quality of Life , Severity of Illness Index
4.
Actas Dermosifiliogr ; 114(4): 291-298, 2023 Apr.
Article in English, Spanish | MEDLINE | ID: mdl-36529273

ABSTRACT

BACKGROUND AND OBJECTIVE: Primary cutaneous lymphomas (PCL) are uncommon. Observations based on the first year of data from the Spanish Registry of Primary Cutaneous Lymphomas (RELCP, in its Spanish abbreviation) of the Spanish Academy of Dermatology and Venereology (AEDV) were published in February 2018. This report covers RELCP data for the first 5 years. PATIENTS AND METHODS: RELCP data were collected prospectively and included diagnosis, treatments, tests, and the current status of patients. We compiled descriptive statistics of the data registered during the first 5 years. RESULTS: Information on 2020 patients treated at 33 Spanish hospitals had been included in the RELCP by December 2021. Fifty-nine percent of the patients were men; the mean age was 62.2 years. The lymphomas were grouped into 4 large diagnostic categories: mycosis fungoides/Sézary syndrome, 1112 patients (55%); primary B-cell cutaneous lymphoma, 547 patients (27.1%); primary CD30+lymphoproliferative disorders, 222 patients (11%), and other T-cell lymphomas, 116 patients (5.8%). Nearly 75% of the tumors were registered in stage I. After treatment, 43.5% achieved complete remission and 27% were stable at the time of writing. Treatments prescribed were topical corticosteroids (1369 [67.8%]), phototherapy (890 patients [44.1%]), surgery (412 patients [20.4%]), and radiotherapy (384 patients [19%]). CONCLUSION: The characteristics of cutaneous lymphomas in Spain are similar to those reported for other series. The large size of the RELCP registry at 5 years has allowed us to give more precise descriptive statistics than in the first year. This registry facilitates the clinical research of the AEDV's lymphoma interest group, which has already published articles based on the RELCP data.


Subject(s)
Dermatology , Lymphoma, T-Cell, Cutaneous , Mycosis Fungoides , Skin Neoplasms , Venereology , Male , Humans , Middle Aged , Female , Lymphoma, T-Cell, Cutaneous/diagnosis , Lymphoma, T-Cell, Cutaneous/epidemiology , Lymphoma, T-Cell, Cutaneous/therapy , Skin Neoplasms/diagnosis , Skin Neoplasms/epidemiology , Skin Neoplasms/therapy , Registries , Mycosis Fungoides/pathology
5.
Actas Dermosifiliogr ; 114(1): 1-8, 2023 Jan.
Article in English, Spanish | MEDLINE | ID: mdl-36030826

ABSTRACT

BACKGROUND AND OBJECTIVES: Hidradenitis suppurativa is a chronic and painful condition with negative impact on daily activity. Little information on the impact of disease-specific factors on educational level and occupational status in hidradenitis suppurativa patients has been reported. We sought to identify how disease-specific factors could influence occupational status and educational level in patients with hidradenitis suppurativa. METHODS: Cross-sectional study of patients with hidradenitis suppurativa seen between September 2017 and September 2018. Disease-specific variables were analyzed to find associations in patients with different educational levels and occupational status. RESULTS: Ninety-eight patients were included. Patients with non-university studies had more frequently≥3 affected areas (22.5% [16/73] vs 4.8% [1/22], p=0.049), a higher number of painful days (8.5 [SD 8.8] vs 4.6 [SD 4.8], p=0.048) and a higher score on the VAS scale (6.7 [SD 2.8] vs 5.0 [3.3], p=0.031). Patients from the inactive group had a significantly increased number of painful days (11.2 [SD 10.4] vs 5.7 [SD 6.2], p=0.004). This group had a greater number of patients with a history of depression (61.3% [19/31] vs 27.4% [17/62], p=0.002) and a higher mean BMI (32.3 [9.1] vs 28.4 [6.4], p=0.016). Late disease onset was significantly associated with being "inactive" (26.7% [8/31] vs 6.5% [4/62], p=0.026). No significant differences between severity scales of hidradenitis suppurativa and educational level or occupational status were found. LIMITATIONS: cross-sectional and single center study. CONCLUSIONS: Pain, ≥3 affected areas, history of depression, higher mean BMI, and late onset of hidradenitis suppurativa, are associated with low education level and inactive occupational status.


Subject(s)
Hidradenitis Suppurativa , Humans , Hidradenitis Suppurativa/complications , Hidradenitis Suppurativa/epidemiology , Cross-Sectional Studies , Pain/etiology , Educational Status , Quality of Life
6.
J Eur Acad Dermatol Venereol ; 32(1): 129-144, 2018 Jan.
Article in English | MEDLINE | ID: mdl-28796920

ABSTRACT

BACKGROUND: The association between hidradenitis suppurativa (HS) and some diseases is becoming relevant in recent years. Providing appropriate management of HS from an early stage requires to include prompt diagnosis and treatment of concomitant diseases and to prevent any potential comorbidity. This approach should consider the adverse events of the drugs used to treat HS potentially related to the onset of a comorbidity. OBJECTIVE: To provide the dermatologist with an accurate, easily used tool that will inform the diagnosis of HS comorbidity, and to facilitate decision-making regarding the referral and treatment of patient with HS-associated comorbidity. METHODS: These recommendations have been developed by a working group composed of seven experts (three dermatologists, a cardiovascular specialist internist, a rheumatologist expert in spondyloarthritis, a gastroenterologist and a psychiatrist) and a team of three methodologist researchers. The expert group selected the HS comorbidities considered in these recommendations through a literature review. The recommendations on diagnostic criteria are based on the relevant clinical practice guidelines for each of the comorbidities and on the recommendations of the experts. The information regarding the repercussion of HS medical treatments on associated comorbid diseases was obtained from the summary of product characteristics of each drug. RESULTS: The comorbidities considered in this guide are as follows: cardiovascular risk factors (diabetes, dyslipidaemia, obesity, hypertension and metabolic syndrome), inflammatory bowel disease, inflammatory joint disorders and psychological disorders (anxiety and depression). In addition, the association between HS and the consumption of alcohol and tobacco is included. The tables and figures are a precise, easy-to-use tool to systematize the diagnosis of comorbidity in patients with HS and facilitate the decision-making process regarding referral and treatment of patients with an associated disease. CONCLUSION: The application of these recommendations will facilitate the dermatologist practice and benefit HS patients' health and quality of life.


Subject(s)
Diabetes Mellitus/epidemiology , Dyslipidemias/epidemiology , Hidradenitis Suppurativa/drug therapy , Hidradenitis Suppurativa/epidemiology , Hypertension/epidemiology , Metabolic Syndrome/epidemiology , Obesity/epidemiology , Alcoholism/diagnosis , Alcoholism/epidemiology , Anxiety/diagnosis , Anxiety/epidemiology , Comorbidity , Decision Support Techniques , Depression/diagnosis , Depression/epidemiology , Diabetes Mellitus/diagnosis , Dyslipidemias/diagnosis , Humans , Hypertension/diagnosis , Inflammatory Bowel Diseases/diagnosis , Inflammatory Bowel Diseases/epidemiology , Metabolic Syndrome/diagnosis , Obesity/diagnosis , Prevalence , Referral and Consultation , Smoking/epidemiology
8.
Actas Dermosifiliogr ; 107 Suppl 2: 27-31, 2016 Sep.
Article in English, Spanish | MEDLINE | ID: mdl-28081767

ABSTRACT

The first description of perianal fistulas and complications in Crohn disease was made 75 years ago by Penner and Crohn. Published studies have subsequently confirmed that perianal fistulas are the most common manifestations of fistulising Crohn disease. Hidradenitis suppurativa was described in 1854 by a French surgeon, Aristide Verneuil. It is a chronic, inflammatory, recurrent and debilitating disease of the pilosebaceous follicle, that usually manifests after puberty with deep, painful and inflamed lesions in the areas of the body with apocrine glands, usually the axillary, inguinal and anogenital regions. The differential diagnosis between hidradenitis suppurativa and Crohn disease can be challenging, especially when the disease is primarily perianal. When they occur simultaneously, hidradenitis suppurativa and Crohn disease show severe phenotypes and patients can respond to anti-tumour necrosis factor therapy, although adalimumab is currently the only treatment with demonstrated efficacy in hidradenitis suppurativa and Crohn disease. In addition, there is sometimes a need for different complementary surgical procedures.


Subject(s)
Crohn Disease/diagnosis , Hidradenitis Suppurativa/diagnosis , Adalimumab/therapeutic use , Anus Diseases/etiology , Anus Diseases/surgery , Biological Factors/therapeutic use , Carcinoma, Squamous Cell/diagnosis , Carcinoma, Squamous Cell/etiology , Colonoscopy , Crohn Disease/complications , Crohn Disease/drug therapy , Crohn Disease/surgery , Cutaneous Fistula/etiology , Cutaneous Fistula/surgery , Diagnosis, Differential , Hidradenitis Suppurativa/complications , Hidradenitis Suppurativa/drug therapy , Hidradenitis Suppurativa/surgery , Humans , Intestinal Fistula/etiology , Intestinal Fistula/surgery , Organ Specificity , Phenotype , Skin Neoplasms/diagnosis , Skin Neoplasms/etiology , Tumor Necrosis Factor-alpha/antagonists & inhibitors
10.
Clin Exp Dermatol ; 40(4): 379-82, 2015 Jun.
Article in English | MEDLINE | ID: mdl-25557739

ABSTRACT

Common variable immunodeficiency (CVID) is a primary immunodeficiency characterized by hypogammaglobulinaemia, T-cell abnormalities and recurrent bacterial infections. Patients with CVID can present granulomatous lesions on both the skin and other organs. When these lesions are the first sign of the disease, the diagnosis can be very challenging. We report the case of a patient with undiagnosed CVID, who presented with necrotizing and sarcoidal granulomas on the skin and synovial membrane as the first appearance of immunodeficiency.


Subject(s)
Common Variable Immunodeficiency/diagnosis , Granuloma/diagnosis , Sarcoidosis/diagnosis , Skin Diseases/diagnosis , Synovial Membrane , Adult , Female , Humans
14.
Actas dermo-sifiliogr. (Ed. impr.) ; 105(2): e1-e6, mar. 2014. tab, ilus
Article in Spanish | IBECS | ID: ibc-120266

ABSTRACT

La hiperplasia angiolinfoide con eosinofilia (HALE) es una enfermedad infrecuente, caracterizada por lesiones angiomatosas solitarias o múltiples que suelen localizarse en el cuero cabelludo y la cara. Presentamos un análisis retrospectivo de 9 casos de HALE. Clínicamente se manifestaban en forma de pápulas o, en algunos casos, de nódulos subcutáneos, agrupados formando lesiones múltiples localizadas en su gran mayoría en el cuero cabelludo, principalmente alrededor de la oreja. También observamos lesiones en localizaciones atípicas, como en otras áreas de la cabeza, el hombro, el cuello y el antebrazo. En estas localizaciones las lesiones adquirían una forma clínica peculiar que dificultaba su diagnóstico y que hay que tener en cuenta ante lesiones únicas, bien delimitadas, de aspecto vascular con ulceración o costra en la superficie. El tratamiento más utilizado fue la cirugía, y aunque se trate de una entidad que se engloba dentro de los procesos benignos, las recidivas fueron frecuentes


Angiolymphoid hyperplasia with eosinophilia (ALHE) is a rare disease characterized by single or multiple angiomatous lesions typically located on the scalp and the face. We present a retrospective analysis of 9 cases of ALHE. The lesions appeared largely as multiple grouped papules or, in some cases, subcutaneous nodules, located mainly on the scalp, particularly around the ear. We also observed lesions in atypical locations, such as areas of the head other than the scalp, and the shoulder, neck, and forearm. At these sites the lesions had an atypical clinical appearance that made diagnosis difficult; this should be borne in mind in patients with single, well-delimited lesions with a vascular appearance and superficial ulceration or crusting. Surgery was the most common treatment in our series, and even though ALHE is considered a benign condition, recurrence was common


Subject(s)
Humans , Angiolymphoid Hyperplasia with Eosinophilia/diagnosis , Skin Diseases, Papulosquamous/diagnosis , Clonal Deletion , Retrospective Studies , Diagnosis, Differential
15.
Actas dermo-sifiliogr. (Ed. impr.) ; 105(2): e7-e12, mar. 2014. tab, ilus
Article in English | IBECS | ID: ibc-120267

ABSTRACT

La hidradenitis ecrina neutrofílica (HEN) es un patrón de reacción clínico-patológico inespecífico, que se ha clasificado como una dermatosis neutrofílica. Normalmente se ha descrito asociada a una enfermedad hematológica maligna. En algunas ocasiones se ha publicado la hidradenitis ecrina neutrofílica asociada a un microorganismo como Serratia, Enterobacter, Staphylococcus y VIH.Nosotros describimos 3 casos de hidradenitis ecrina infecciosa secundarias a infecciones por Nocardia, Mycobacterium chelonae y Staphylococcus aureus. Las biopsias mostraron un denso infiltrado perivascular y periductal de neutrófilos en la dermis. En las glándulas ecrinas se apreciaba degeneración vacuolar y necrosis de las células epiteliales, predominantemente en la porción secretora. Nuestros casos apoyan que la HEN es una respuesta cutánea característica a un estímulo inespecífico. Los hallazgos clínicos e histopatológicos de la HEN infecciosa o no infecciosa son generalmente indistinguibles. Cuando se considera un caso de HEN se debería investigar la posibilidad de una causa infecciosa y realizar un cultivo. En este artículo hemos revisado los diagnósticos diferenciales clínicos e histopatológicos y la literatura publicada de esta entidad (AU)


Neutrophilic eccrine hidradenitis (NEH) is a nonspecific clinicopathological reaction pattern, classified as a neutrophilic dermatosis, that usually develops in patients receiving chemotherapy for a hematologic malignancy. More rarely, it has been reported in association with infectious agents such as Serratia and Enterobacter species, Staphylococcus aureus, and human immunodeficiency virus. We describe 3 cases of infectious eccrine hidradenitis secondary to infection with Nocardia species, Mycobacterium chelonae, and S aureus. Histological findings revealed a dense infiltrate with perivascular and periductal neutrophils in the dermis. In the eccrine glands, there was vacuolar degeneration and necrosis of the epithelial cells. Our cases support the assertion that NEH is a characteristic cutaneous response to non specific stimuli. Clinical and histopathological findings of infectious and noninfectious NEH are generally indistinguishable and when NEH is suspected, the possibility of an infectious association must be investigated by skin tissue culture. In this article we also discuss differential diagnoses and review the literature (AU)


Subject(s)
Humans , Hidradenitis Suppurativa/diagnosis , Infections/complications , Hematologic Diseases/complications , Risk Factors , Nocardia/pathogenicity , Staphylococcus aureus/pathogenicity , Mycobacterium chelonae/pathogenicity
17.
Actas Dermosifiliogr ; 105(2): e7-12, 2014 Mar.
Article in English, Spanish | MEDLINE | ID: mdl-24011437

ABSTRACT

Neutrophilic eccrine hidradenitis (NEH) is a nonspecific clinicopathological reaction pattern, classified as a neutrophilic dermatosis, that usually develops in patients receiving chemotherapy for a hematologic malignancy. More rarely, it has been reported in association with infectious agents such as Serratia and Enterobacter species, Staphylococcus aureus, and human immunodeficiency virus. We describe 3 cases of infectious eccrine hidradenitis secondary to infection with Nocardia species, Mycobacterium chelonae, and S aureus. Histological findings revealed a dense infiltrate with perivascular and periductal neutrophils in the dermis. In the eccrine glands, there was vacuolar degeneration and necrosis of the epithelial cells. Our cases support the assertion that NEH is a characteristic cutaneous response to nonspecific stimuli. Clinical and histopathological findings of infectious and noninfectious NEH are generally indistinguishable and when NEH is suspected, the possibility of an infectious association must be investigated by skin tissue culture. In this article we also discuss differential diagnoses and review the literature.


Subject(s)
Hidradenitis/microbiology , Mycobacterium Infections, Nontuberculous , Mycobacterium chelonae , Nocardia Infections , Staphylococcal Infections , Adult , Aged, 80 and over , Hidradenitis/diagnosis , Humans , Male , Middle Aged , Mycobacterium Infections, Nontuberculous/diagnosis , Nocardia Infections/diagnosis , Staphylococcal Infections/diagnosis
18.
Actas Dermosifiliogr ; 105(2): e1-6, 2014 Mar.
Article in English, Spanish | MEDLINE | ID: mdl-23845664

ABSTRACT

Angiolymphoid hyperplasia with eosinophilia (ALHE) is a rare disease characterized by single or multiple angiomatous lesions typically located on the scalp and the face. We present a retrospective analysis of 9 cases of ALHE. The lesions appeared largely as multiple grouped papules or, in some cases, subcutaneous nodules, located mainly on the scalp, particularly around the ear. We also observed lesions in atypical locations, such as areas of the head other than the scalp, and the shoulder, neck, and forearm. At these sites the lesions had an atypical clinical appearance that made diagnosis difficult; this should be borne in mind in patients with single, well-delimited lesions with a vascular appearance and superficial ulceration or crusting. Surgery was the most common treatment in our series, and even though ALHE is considered a benign condition, recurrence was common.


Subject(s)
Angiolymphoid Hyperplasia with Eosinophilia/pathology , Adolescent , Adult , Female , Humans , Male , Middle Aged , Retrospective Studies
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