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1.
Radiologe ; 61(6): 563-571, 2021 Jun.
Article in German | MEDLINE | ID: mdl-34002282

ABSTRACT

CLINICAL/METHODOLOGICAL ISSUE: Chronic pancreatitis (CP) is a long-lasting inflammation of the pancreas that changes the normal structure and function of the organ. There are a wide range of inflammatory pancreatic diseases, of which some entities, such as focal pancreatitis (FP) or "mass-forming pancreatitis," can mimic pancreatic ductal adenocarcinoma (PDAC). As a consequence, a misdiagnosis can lead to avoidable and unnecessary surgery or delay of therapy. STANDARD RADIOLOGICAL METHODS: The initial imaging method used in pancreatic diseases is ultrasound due to its availability and low cost, followed by contrast-enhanced computed tomography (CE-CT), which is considered a workhorse in the diagnostic work-up of diseases of the pancreas. Magnetic resonance imaging (MRI) and/or MR cholangiopancreatography (MRCP) can be used as a problem-solving tool to distinguish between solid and cystic lesions, and to rule out abnormalities in the pancreatic ducts, such as those associated with recurrent acute pancreatitis (AP) or to show early signs of CP. MRCP has essentially replaced diagnostic endoscopic retrograde cholangiopancreatography (ERCP) in the initial assessment before any therapeutic intervention. PRACTICAL RECOMMENDATION: The following review article summarizes the relevant features of CT and MRI that can help to make the diagnosis of CP and to aid in the differentiation between focal pancreatitis and PDAC, even in difficult cases.


Subject(s)
Pancreatic Neoplasms , Pancreatitis, Chronic , Acute Disease , Cholangiopancreatography, Endoscopic Retrograde , Humans , Magnetic Resonance Imaging , Pancreatic Neoplasms/diagnostic imaging , Pancreatitis, Chronic/diagnostic imaging
2.
Radiologe ; 51(8): 688-96, 2011 Aug.
Article in German | MEDLINE | ID: mdl-21809146

ABSTRACT

A profound knowledge of the various benign focal hepatic lesions and selection of the most suitable radiological examination modality is essential for achieving an accurate characterization of a hepatic lesion and in turn will determine the further patient management. This will avoid unnecessary agitation to both patient and the referring clinician and limits time-consuming, costly and risky biopsies to an absolute minimum. The following article will discuss the typical and atypical appearances of the most frequent and clinically relevant benign focal hepatic lesions with ultrasound, computed tomography and magnetic resonance imaging.


Subject(s)
Image Enhancement/methods , Image Processing, Computer-Assisted/methods , Liver Diseases/diagnosis , Liver Neoplasms/diagnosis , Liver/pathology , Magnetic Resonance Imaging/methods , Tomography, X-Ray Computed/methods , Ultrasonography/methods , Adenoma, Liver Cell/diagnosis , Adenoma, Liver Cell/pathology , Cholangiopancreatography, Magnetic Resonance/methods , Contrast Media/administration & dosage , Cysts/diagnosis , Cysts/pathology , Diagnosis, Differential , Diffusion Magnetic Resonance Imaging/methods , Focal Nodular Hyperplasia/diagnosis , Focal Nodular Hyperplasia/pathology , Hamartoma/diagnosis , Hamartoma/pathology , Hemangioma/diagnosis , Hemangioma/pathology , Humans , Liver Diseases/pathology , Liver Neoplasms/pathology , Sensitivity and Specificity
3.
Rofo ; 181(6): 587-92, 2009 Jun.
Article in English | MEDLINE | ID: mdl-19353488

ABSTRACT

PURPOSE: To qualitatively and quantitatively compare gadoxate-enhanced T 1-weighted MR cholangiography at magnetic field strengths of 1.5 T and 3.0 T. MATERIALS AND METHODS: A total of 40 patients with a non-dilated biliary system were retrospectively included in the study. T 1-weighted MR cholangiography 20 min after IV administration of 0.025 mmol/kg gadoxate (Primovist) was performed in 20 patients at 1.5 T and in another 20 patients at 3.0 T. Contrast-to-noise ratios (CNR) of the biliary system (common bile duct - CBD, right hepatic duct - RHD, left hepatic duct - LHD) compared to the periductal tissue were measured. Two radiologists also qualitatively assessed the visibility of the intrahepatic and extrahepatic biliary system using a six-point rating scale. The Mann-Whitney U-test and Pearson's correlation coefficient were used for statistical analysis. RESULTS: The CNRs of the intrahepatic and extrahepatic hepatic bile ducts were significantly higher at 3.0 T. Qualitative analysis showed a significant superiority for 3.0 T in the delineation of the intrahepatic biliary system (RHD, LHD, segmental ducts). CONCLUSION: Gadoxate-enhanced T 1-w MR cholangiography at 3.0 T offers better delineation of the intrahepatic biliary system in comparison to imaging at 1.5 T.


Subject(s)
Cholangiopancreatography, Magnetic Resonance/methods , Gadolinium DTPA , Image Enhancement/methods , Liver Diseases/diagnosis , Contrast Media , Female , Humans , Male , Middle Aged , Reproducibility of Results , Sensitivity and Specificity
4.
Radiologe ; 49(6): 543-54; quiz 555-6, 2009 Jun.
Article in German | MEDLINE | ID: mdl-19241053

ABSTRACT

The abdominal cavity is subdivided into the peritoneal cavity, lined by the parietal peritoneum, and the extraperitoneal space. It extends from the diaphragm to the pelvic floor. The visceral peritoneum covers the intraperitoneal organs and part of the pelvic organs. The parietal and visceral layers of the peritoneum are in sliding contact; the potential space between them is called the peritoneal cavity and is a part of the embryologic abdominal cavity or primitive coelomic duct. To understand the complex anatomical construction of the different variants of plicae and recesses of the peritoneum, an appreciation of the embryologic development of the peritoneal cavity is crucial. This knowledge reflects the understanding of the peritoneal anatomy, deep knowledge of which is very important in determining the cause and extent of peritoneal diseases as well as in decision making when choosing the appropriate therapeutic approach, whether surgery, conservative treatment, or interventional radiology.


Subject(s)
Magnetic Resonance Imaging , Mesentery/diagnostic imaging , Mesentery/pathology , Peritoneal Diseases/diagnosis , Peritoneum/diagnostic imaging , Peritoneum/pathology , Tomography, X-Ray Computed , Humans
5.
Radiologe ; 49(7): 637-51; quiz 652-4, 2009 Jul.
Article in German | MEDLINE | ID: mdl-19224192

ABSTRACT

Peritoneal diseases can be seen in the different imaging modalities either as fluid collections or solid tumors along the ligaments, mesenteries, and spaces of the peritoneal cavity. The broad spectrum of different abnormalities includes inflammatory, infectious, traumatic, and neoplastic diseases. In this article, a large variety of peritoneal abnormalities such as ascites, peritonitis, intraperitoneal hemorrhage, and both primary and secondary peritoneal tumors are discussed. The different imaging modalities, characteristic radiological features, and typical pathways of anatomic spread are explained.


Subject(s)
Magnetic Resonance Imaging/methods , Mesentery , Peritoneal Diseases/diagnosis , Tomography, X-Ray Computed/methods , Ultrasonography/methods , Humans , Mesentery/diagnostic imaging , Mesentery/pathology , Mesentery/ultrastructure
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