ABSTRACT
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Subject(s)
Humans , Male , Middle Aged , Pharyngeal Muscles/physiopathology , Pharyngeal Diseases/diagnosis , Hernia/diagnosis , Herniorrhaphy , Head and Neck Neoplasms/diagnosis , Diagnosis, Differential , Voice Disorders/etiologySubject(s)
Hernia , Pharyngeal Diseases , Hernia/diagnosis , Herniorrhaphy , Humans , Male , Middle Aged , Pharyngeal Diseases/diagnosis , Pharyngeal Diseases/surgeryABSTRACT
Mixed tumours of the parotid gland are rare in childhood and recurrence of this tumour is infrequent. Some authors report a higher rate of recurrence with some histological subtypes, like hypocellular variant. Female sex and young age at initial treatment are also risk factor for recurrence. Also the first surgical treatment, tumoure nucleation or parotidectomy, has been implicated as a cause for recurrence. We present a case of a multicentric doubly recurrent parotid pleomorphic adenoma, 7 and 14 years after tumour enucleation, in a 9-year-old child. All the nodules resected showed the hypocellular variant of pleomorphic adenoma. We consider the relationships between the choice of treatment, the histologic subtypes of pleomorphic adenomas and multifocal tumours and recurrence. In this case, we believe the recurrence was related to surgical enucleation previously performed and the hypocellular histological subtype. We conclude that tumour enucleation is a risk factor for recurrence and total parotidectomy is the treatment of choice for pleomorphic parotid adenoma also in childhood (AU)
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Subject(s)
Humans , Female , Adolescent , Adenoma, Pleomorphic/pathology , Parotid Neoplasms/pathology , Mixed Tumor, Malignant/pathology , Neoplasm Recurrence, LocalABSTRACT
Wegeners granulomatosis is a multisystemic granulomatous vasculitis that predominantly affects the airways and the kidneys, but may affect any organ. Otorhinolaryngological manifestations may be oral ulcers, gingival swelling or septal perforations that can cause saddle nose deformities, rhinitis, sinusitis and hearing loss. The oral ulcers usually occur when the disease is advanced. Renal involvement is characterized by focal and segmental glomerulosclerosis, and determines the evolution. The diagnosis is made by clinical symptoms and signs, the presence of c-ANCA and a positive biopsy. The anatomic pathology is characterized by vasculitis, granulomatous inflammation with multinuclear giant cells and necrosis. The prognosis has improved as a result of treatment with immunosuppressants associated with corticosteroids. We report a case of a 53-year-old patient with Wegeners granulomatosis with oral manifestation, which began as chronic mastitis (AU)
Subject(s)
Humans , Male , Middle Aged , Granulomatosis with Polyangiitis/diagnosis , Oral Ulcer/etiology , Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis/diagnosis , Immunosuppressive Agents/therapeutic use , Adrenal Cortex Hormones/therapeutic useABSTRACT
Mixed tumours of the parotid gland are rare in childhood and recurrence of this tumour is infrequent. Some authors report a higher rate of recurrence with some histological subtypes, like hypocellular variant. Female sex and young age at initial treatment are also risk factor for recurrence. Also the first surgical treatment, tumour enucleation or parotidectomy, has been implicated as a cause for recurrence. We present a case of a multicentric doubly recurrent parotid pleomorphic adenoma, 7 and 14 years after tumour enucleation, in a 9-year-old child. All the nodules resected showed the hypocellular variant of pleomorphic adenoma. We consider the relationships between the choice of treatment, the histologic subtypes of pleomorphic adenomas and multifocal tumours and recurrence. In this case, we believe the recurrence was related to surgical enucleation previously performed and the hypocellular histological subtype. We conclude that tumour enucleation is a risk factor for recurrence and total parotidectomy is the treatment of choice for pleomorphic parotid adenoma also in childhood.
Subject(s)
Adenoma, Pleomorphic/pathology , Neoplasm Recurrence, Local/pathology , Parotid Neoplasms/pathology , Adenoma, Pleomorphic/surgery , Adolescent , Child , Female , Humans , Neoplasm Recurrence, Local/surgery , Parotid Neoplasms/surgeryABSTRACT
Wegener's granulomatosis is a multisystemic granulomatous vasculitis that predominantly affects the airways and the kidneys, but may affect any organ. Otorhinolaryngological manifestations may be oral ulcers, gingival swelling or septal perforations that can cause saddle nose deformities, rhinitis, sinusitis and hearing loss. The oral ulcers usually occur when the disease is advanced. Renal involvement is characterized by focal and segmental glomerulosclerosis, and determines the evolution. The diagnosis is made by clinical symptoms and signs, the presence of c-ANCA and a positive biopsy. The anatomic pathology is characterized by vasculitis, granulomatous inflammation with multinuclear giant cells and necrosis. The prognosis has improved as a result of treatment with immunosuppressants associated with corticosteroids. We report a case of a 53-year-old patient with Wegener's granulomatosis with oral manifestation, which began as chronic mastitis.
Subject(s)
Granulomatosis with Polyangiitis/complications , Mouth Diseases/etiology , Female , Humans , Middle AgedABSTRACT
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Subject(s)
Humans , Female , Aged , Hyoid Bone/abnormalities , Vocal Cord Paralysis/etiology , Pharynx/physiopathology , Deglutition Disorders/etiology , Diagnosis, DifferentialSubject(s)
Branchial Region/abnormalities , Deglutition Disorders/etiology , Hyoid Bone/abnormalities , Ligaments/abnormalities , Neck Pain/etiology , Ossification, Heterotopic/etiology , Aged , Branchial Region/diagnostic imaging , Branchial Region/embryology , Female , Head Movements , Humans , Hyoid Bone/diagnostic imaging , Hyoid Bone/embryology , Ligaments/diagnostic imaging , Ligaments/embryology , Ossification, Heterotopic/diagnostic imaging , Paresthesia/etiology , Syndrome , Tomography, X-Ray ComputedABSTRACT
Several histopathological modalities of tumours can grow in the rhinopharynx. Solitary extramedullary plasmocytoma (SEP) is a low frequent variety of low-grade lymphoma. The aim of this work is to present a new case of SEP localized in rhinopharynx and to perform a review of diagnostic and therapeutic protocols of these neoplasias. They must be taken into account in the differential diagnosis of nasopharyngeal tumours.
Subject(s)
Nasopharyngeal Neoplasms , Plasmacytoma , Aged , Humans , Male , Nasopharyngeal Neoplasms/diagnosis , Nasopharyngeal Neoplasms/therapy , Plasmacytoma/diagnosis , Plasmacytoma/therapyABSTRACT
La nasofaringe es el asiento de tumores de muy variada naturaleza. El plasmocitoma solitario extramedular (PSE) es una variante poco frecuente de linfoma de bajo grado, cuya localización a este nivel es muy rara. El objetivo de este trabajo es presentar un nuevo caso de PSE localizado a nivel de la amígdala tubárica y revisar los protocolos diagnósticos y terapéuticos de este tipo infrecuente de neoplasias que deben tenerse en cuenta en el diagnóstico diferencial de los tumores de nasofaringe (AU)
Several histopathological modalities of tumours can grow in the rhinopharynx. Solitary extramedullary plasmocytoma (SEP) is a low frequent variety of low-grade lymphoma. The aim of this work is to present a new case of SEP localized in rhinopharynx and to perform a review of diagnostic and therapeutic protocols of these neoplasias. They must be taken into account in the differential diagnosis of nasopharyngeal tumours (AU)
Subject(s)
Humans , Male , Aged , Plasmacytoma/pathology , Nasopharyngeal Neoplasms/pathology , Diagnosis, DifferentialABSTRACT
Chondromyxoid fibroma is an infrequent bone tumour in the craniofacial bones and exceptional in the paranasal sinuses. This unusual location, its non-specific clinical manifestation and aggressive behaviour with local destruction and a high recurrence rate can complicate precise diagnosis and treatment.
Subject(s)
Ethmoid Sinus , Fibroma , Neoplasms, Multiple Primary , Paranasal Sinus Neoplasms , Fibroma/diagnosis , Humans , Male , Maxillary Sinus Neoplasms/diagnosis , Middle Aged , Neoplasms, Multiple Primary/diagnosis , Paranasal Sinus Neoplasms/diagnosisABSTRACT
El fibroma condromixoide es un tumor óseo infrecuente en los huesos craneofaciales y excepcional en los senos paranasales. Esta localización inusual, la clínica inespecífica, la agresividad por destrucción local y la tasa elevada de recurrencia complican el diagnóstico y la indicación terapéutica
Chondromyxoid fibroma is an infrequent bone tumour in the craniofacial bones and exceptional in the paranasal sinuses. This unusual location, its non-specific clinical manifestation and aggressive behaviour with local destruction and a high recurrence rate can complicate precise diagnosis and treatment
Subject(s)
Humans , Male , Middle Aged , Fibroma/diagnosis , Ethmoid Sinus , Neoplasms, Multiple Primary/diagnosis , Paranasal Sinus Neoplasms/diagnosis , Maxillary Sinus Neoplasms/diagnosisABSTRACT
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Subject(s)
Humans , Male , Adult , Zenker Diverticulum/etiology , Esophagus/injuries , Diagnosis, Differential , Iatrogenic Disease , Deglutition Disorders/complications , Bone Plates , Cervical VertebraeABSTRACT
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Most salivary gland tumors are benign, malignant lesions accounting for 15-30% of the total. The most frequent site of salivary gland neoplasms is the parotid gland (80% of all cases). We present a case of malignant fibrohistiocytoma with atypical features due to its location (in the parotid region), size and rapid growth. Generally, this type of tumor arises in the lower limbs and in the abdomen. When located in the parotid gland, these lesions appear as a firm, slow growing and painless mass. Due to the low frequency of such lesions and their clinical behavior, the imaging studyand fine-needle aspiration biopsy findings tend to diagnose them as pleomorphic adenoma. The definitive diagnosis requires microscopic study of the resection piece using immunohistochemical techniques. The treatment of choice is surgery, occasionally associated to radiotherapy. The success of treatment is dependent upon complete resection of the tumor - long term follow-up being necessary due to the risk of recurrence or distant metastasis