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1.
Organ Stud ; 44(4): 659-675, 2023 Apr.
Article in English | MEDLINE | ID: mdl-37007276

ABSTRACT

This essay encourages scholars of management and organization studies (MOS) to critically reflect on how Indigenous peoples and their knowledges have been, and continue to be, systemically discriminated against. This discrimination is the result of colonization; it has deeply impacted and continues to affect which knowledges and practices are valued and embraced. The impact of colonization is mirrored in MOS via processes and actions within the academic setting and our business schools. The result is the continued marginalization of Indigenous peoples and their knowledges. We propose a shift in how MOS scholars approach research in relation to non-western societies to counter, and hopefully end, these continued practices of discrimination in our business schools. Specifically, we argue that demarginalizing Indigenous research in academia and going beyond 'cosmetic indigenization' in our business schools are new, collaborative ways of rethinking indigeneity and breaking down the current barriers in MOS that reinforce and perpetuate the systemic discrimination against Indigenous peoples, their knowledges and practices.

2.
Biosens Bioelectron ; 129: 231-237, 2019 Mar 15.
Article in English | MEDLINE | ID: mdl-30287174

ABSTRACT

Early screening of gastric cancer is a critical importance for the improvement of patients' survival rate. Here, a polyethylene coating Lamb (PE-Lamb) microfluidic device with immune layer for gastric cancer label-free detection was constructed. Two serum pepsinogen 1 (PG1) and pepsinogen 2 (PG2) biomarkers were applied to screen and predict the appearance of gastric cancer. Compared with enzyme-linked immunosorbent assay (ELISA), this method achieved a higher sensitivity and less time (40 min vs 120 min). The limit of detections (LOD) were reached 60 pg/mL for PG1 and 30 pg/mL for PG2, which have two orders of magnitude lower than traditional ELISA. The linearity coefficient indexes (R2) for PG1 and PG2 were 0.992 and 0.953 respectively, which is similar to that of ELISA. In addition, PG1 and PG2 mixed antigens sample with human serum was detected by PE-Lamb approach, and the frequency response showed high reproducibility and specificity. The results indicate that PE-lamb diagnostic technique is a novel and promising method for high-throughput screening and early diagnosis of gastric cancer.


Subject(s)
Biosensing Techniques/instrumentation , Lab-On-A-Chip Devices , Pepsinogen A/blood , Pepsinogen C/blood , Polyethylene/chemistry , Biosensing Techniques/economics , Equipment Design , Humans , Lab-On-A-Chip Devices/economics , Limit of Detection , Pepsinogen A/analysis , Pepsinogen C/analysis , Reproducibility of Results , Stomach Neoplasms/blood , Stomach Neoplasms/diagnosis , Surface Properties , Time Factors
3.
Sensors (Basel) ; 12(8): 10369-80, 2012.
Article in English | MEDLINE | ID: mdl-23112604

ABSTRACT

In this paper, a liquid multi-parameter decoupling method with only one Lamb wave sensor is presented. In a Lamb wave sensor, antisymmetric modes (A(01) mode for low frequency, A(03) mode for high frequency) and symmetric modes (S(0) mode) are used to detect multiple parameters of a liquid, such as its density, sound velocity, and viscosity. We found they can play very different roles in the detections. For example, the A(01) mode is very sensitive to the liquid's density but the A(03) mode is sensitive to the sound velocity. Here, the A(0) mode is used to identify the density of the detected liquid and with this density value we obtained the viscosity by the amplitude shifts of the S(0) mode. This could be a way to distinguish an unknown liquid with high sensitivity or to solve the problem of selectivity of label-free detection on biosensors.


Subject(s)
Acoustics/instrumentation , Chemistry Techniques, Analytical/instrumentation , Signal Processing, Computer-Assisted , Solutions/chemistry , Biosensing Techniques/instrumentation , Bromides/chemistry , Chemistry Techniques, Analytical/methods , Electronics , Microtechnology/instrumentation , Sodium Chloride/chemistry , Sodium Compounds/chemistry , Solutions/analysis , Sound , Viscosity
4.
Article in English | MEDLINE | ID: mdl-18019253

ABSTRACT

The capability to accurately handle liquids in small volumes is a key point for the development of lab-on-chip devices. In this paper, we investigate an application of surface acoustic waves (SAW) for positioning micro-droplets. A SAW device based on a 2 x 2 matrix of inter-digital transducers (IDTs) has been fabricated on a (YXI)/128 degrees LiNbO3 substrate, which implies displacement and detection in two dimensions of droplets atop a flat surface. Each IDT operates at a given frequency, allowing for an easy addressing of the active channel. Furthermore, very low cross-talk effects were observed as no frequency mixing arose in our device. Continuous as well as pulsed excitations of the IDTs have been studied, yielding, respectively, continuous and step-by-step droplet displacement modes. In addition, we also have used these two excitation types to control the velocity and the position of the droplets. We also have developed a theoretical analysis of the detection mode, which has been validated by experimental assessment.

5.
Ultrasonics ; 40(1-8): 349-53, 2002 May.
Article in English | MEDLINE | ID: mdl-12159963

ABSTRACT

A water droplet placed on a vibrating surface moves toward the antinode of the vibration. The acoustic radiation pressure can explain this non-linear phenomenon. In this paper, the use of a piezoelectric actuator to produce a displacement of liquid droplets is pointed out. Due to geometry of the actuator and the position of piezoelectric ceramics, it is possible to generate stationary modes in the structure where the nodal lines can move.

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