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1.
Antonie Van Leeuwenhoek ; 112(6): 961-964, 2019 Jun.
Article in English | MEDLINE | ID: mdl-30663019

ABSTRACT

We present a post-operative infection caused by a methicillin-resistant Staphylococcus aureus strain, previously isolated in the preoperative screening, in a patient submitted to femoral osteosynthesis, successfully treated with oral ciprofloxacin. The isolate exhibited in vitro resistance to ciprofloxacin, Staphylococcal Cassette Chromosome mec type IV, it was negative for the lukS-PV Panton-Valentine leucocidin gene and belonged to ST2594 in multilocus sequence typing analysis. Whole genome sequencing revealed a genome size of 2,818,289 base pairs. The annotated genomes of ST2594 and N315 strains were compared, looking for genes related to virulence and resistance. The lack of the tst, sec, sel genes, associated with a mutation in the clfA gene, may partially explain the low morbity in this case.


Subject(s)
Methicillin-Resistant Staphylococcus aureus/isolation & purification , Postoperative Complications/microbiology , Staphylococcal Infections/microbiology , Aged, 80 and over , Anti-Bacterial Agents/pharmacology , Bacterial Proteins/genetics , Ciprofloxacin/pharmacology , Drug Resistance, Bacterial , Female , Genome, Bacterial , Groin/microbiology , Humans , Methicillin-Resistant Staphylococcus aureus/classification , Methicillin-Resistant Staphylococcus aureus/drug effects , Methicillin-Resistant Staphylococcus aureus/genetics , Microbial Sensitivity Tests , Postoperative Complications/drug therapy , Preoperative Period , Staphylococcal Infections/drug therapy , Virulence Factors/genetics , Whole Genome Sequencing
2.
Rev Bras Ortop ; 45(4): 362-74, 2010.
Article in English | MEDLINE | ID: mdl-27022565

ABSTRACT

OBJECTIVE: To evaluate the clinical, functional and radiographic results from talar neck fractures in patients treated at the Foot and Ankle Surgery Group of Santa Casa de Sao Paulo. METHOD: We evaluated 20 patients. The mean follow-up time was 71 months. One fracture was classified as Hawkins Type I, 12 as Hawkins type II, five as Hawkins type III, two as Hawkins type IV and four fractures were open. RESULTS: One patient was treated conservatively, 16 were treated with open reduction and internal fixation (three with primary subtalar arthrodesis), one was treated with talectomy and two with tibiotalocalcaneal arthrodesis. The reduction obtained was anatomical in seven feet, acceptable in six feet and poor in four. Seven patients had early complications. There was one case of delayed consolidation and four of talar body osteonecrosis. Four patients required secondary reconstruction procedures. No significant radiographic impairment of the ankle joint was found in 62% of the patients and of the subtalar joint in 25%. Of the patients who did not undergo secondary procedures, 81% complained about the treated foot, 37.5% showed some deformity, 44% presented diminished sensitivity and 50% had to retire from work. The mean loss of motion in the ankle was 49%, and in the subtalar joint, 80%. The average AOFAS score was 73 points. CONCLUSION: Talar neck fractures are associated with high rates of clinical, functional and radiographic complications.

3.
Rev. bras. ortop ; 45(4): 362-374, 2010. ilus, tab
Article in Portuguese | LILACS | ID: lil-560751

ABSTRACT

OBJETIVO: Avaliar o resultado clínico-funcional e radiográfico dos pacientes com fraturas do colo do tálus tratados pelo Grupo de Cirurgia do Pé e Tornozelo da Santa Casa de São Paulo. MÉTODO: Avaliamos 20 pacientes, com tempo médio de seguimento de 71 meses: um com fratura do tipo I, 12 do tipo II, cinco do tipo III e dois do tipo IV, sendo quatro fraturas expostas. RESULTADOS: Um paciente foi tratado incruentamente, 16 com RAFI (três com artrodese subtalar primária), um com talectomia e dois com artrodese tibiotalocalcaneana. A redução obtida foi classificada como anatômica em sete pés, aceitável em seis, e ruim em quatro. Sete pacientes apresentaram complicações precoces. Houve um retardo de consolidação e quatro osteonecroses do corpo do tálus. Quatro pacientes necessitaram de procedimentos reconstrutivos secundários. Sessenta e dois porcento dos pacientes não apresentaram comprometimento radiográfico importante na articulação do tornozelo e 25 por cento na articulação subtalar. Dos pacientes não submetidos a procedimentos secundários, 81 por cento apresentaram queixas referentes ao pé tratado, 37,5 por cento apresentaram alguma deformidade, 44 por cento déficit sensitivo e 50 por cento estavam aposentados. A perda média de movimento do tornozelo foi de 49 por cento e da subtalar 80 por cento. A pontuação média pela escala AOFAS foi de 73 pontos. CONCLUSÃO: A fratura do colo do tálus leva a alta incidência de complicações clínico-funcionais e radiográficas.


OBJETIVE: To evaluate the clinical, functional and radiographic outcomes of talar neck fractures in patients treated at the Foot and Ankle Surgery Group of the Santa Casa de São Paulo. METHOD: 20 patients were evaluated. Mean follow-up time was 71 months. One fracture was classified as Hawkins Type I, 12 as Hawkins type II, five as Hawkins type III, two as Hawkins type IV, and four fractures were open. RESULTS: One patient was treated conservatively, 16 were treated with ORIF (three with primary subtalar arthrodesis), one treated with talectomy and two with tibiotalocalcaneal arthrodesis. The reduction was anatomical in seven feet, acceptable in six feet and poor in four. Seven patients had early complications. There was one delay of consolidation and four talar body osteonecrosis. No signs or minimal signs of radiographic arthritis of the affected ankles were found in 62 percent of the patients and 25 percent of affected subtalar joints. Of the 16 patients who did not require secondary procedures, 81 percent complained about the treated foot, 37.5 percent showed some deformity, 44 percent had decreased skin sensitivity and 50 percent never returned to work. The mean loss of motion in the ankle was 49 percent, and in the subtalar joint, 80 percent. The average AOFAS score was 73 points. CONCLUSION: Talar neck fractures are associated with high rates of clinical, functional and radiographic complications.


Subject(s)
Humans , Male , Female , Adolescent , Adult , Middle Aged , Fractures, Bone/complications , Outcome Assessment, Health Care , Talus/injuries
4.
Rev. bras. ortop ; 41(9): 352-360, set. 2006. ilus, tab
Article in Portuguese | LILACS | ID: lil-437571

ABSTRACT

Objetivo: A deformidade em varo do cotovelo é uma complicação comum das fraturas supracondilares. A principal queixa é a cosmética e a osteotomia supracondilar é o tratamento de escolha. Métodos: Entre outubro de 1991 e maio de 2003, 26 pacientes foram operados visando o tratamento dessa deformidade. A média de idade no momento da fratura era de cinco anos e quatro meses e o tempo médio entre a fratura e a osteotomia foi de 81 meses. A média do ângulo de carregamento era de -21°. Todos os pacientes foram submetidos a ressecção de cunha óssea com base lateral. Quanto à osteossíntese, em 14 pacientes foi feita com dois fios de Kirschner cruzados e, nos restantes, com placa e parafusos. Em 11 pacientes foi feita uma medialização do fragmento distal buscando evitar o desenvolvimento de proeminência lateral. Resultados: Ocorreram complicações em 13 pacientes: em um paciente, fratura da superfície articular durante a osteotomia; em sete, a cunha ressecada foi insuficiente e em cinco houve perda da redução por falha da fixação. Num tempo de seguimento médio de 56 meses, as principais queixas foram: persistência da deformidade em varo, proeminência lateral, dor e limitação da mobilidade. Pelo critério de avaliação anatômica, houve 11 resultados excelentes, seis bons e nove ruins; e pelo critério de avaliação funcional, oito resultados excelentes, nove bons, quatro regulares e cinco ruins. Conclusão: Os autores concluem que planejamento e execução mais cuidadosa da cunha e fixação suficientemente rígida podem minimizar as complicações.


Subject(s)
Humans , Male , Female , Elbow/surgery , Elbow/injuries , Osteotomy , Follow-Up Studies , Outcome Assessment, Health Care
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