ABSTRACT
The endobronchial localization of Hodgkin's disease is a rare entity which is often confused with endobronchial tuberculosis in our setting. We report the case of a 16 years old female who presented with 6 months history of dry cough, hemoptysis, dyspnea, dysphagia and dysphonia. The chest radiography showed a mediastinal and pulmonary opacity. The chest CT scan found enlarged mediastinal lymph nodes. The bronchial biopsy and peripheral lymph node biopsy confirmed Hodgkin's disease with endobronchial localization. The patient received chemotherapy (ABVD protocol) and radiotherapy with a favorable follow up.
Subject(s)
Antineoplastic Combined Chemotherapy Protocols/therapeutic use , Bronchial Neoplasms/diagnosis , Hodgkin Disease/diagnosis , Adolescent , Biopsy , Bleomycin/therapeutic use , Bronchial Neoplasms/drug therapy , Bronchial Neoplasms/pathology , Dacarbazine/therapeutic use , Doxorubicin/therapeutic use , Female , Follow-Up Studies , Hodgkin Disease/drug therapy , Hodgkin Disease/pathology , Humans , Lymph Nodes/pathology , Tomography, X-Ray Computed , Vinblastine/therapeutic useABSTRACT
Hydatid cyst is an infectious disease which is quite frequent in Morocco. Pelvic and pancreatic locations of this parasitic infection are rare, namely exceptional. We report the case of a 66-year old patient who was operated for liver hydatic cyst 6 years before, presenting for chest pain associated with hydatidoptysis. Chest X-ray objectified left hydropneumothorax. Thoraco-abdominopelvic CT showed mediastinal liquid mass as well as multiple hepatic, pancreatic (isthmus), pelvic and left under diaphragmatic cystic lesions. Hydatid serology was positive. Treatment involved thoracotomy associated with medical treatment.
Subject(s)
Echinococcosis, Hepatic/diagnosis , Echinococcosis/diagnosis , Pancreatic Diseases/diagnosis , Pelvis/parasitology , Aged , Animals , Chest Pain/parasitology , Echinococcosis/therapy , Echinococcosis, Hepatic/therapy , Female , Humans , Morocco , Pancreatic Diseases/parasitology , Pancreatic Diseases/therapy , Thoracotomy/methods , Tomography, X-Ray ComputedABSTRACT
The lungs receive the entire venous drainage of the body. This explains the high incidence of pleuropulmonary metastases originating from several cancers. The goal of this is to study the clinical manifestations of pleuro-pulmonary metastases originating from extra-thoracic cancers. We conducted a retrospective study of patients with pleuro-pulmonary metastasis whose data were collected in our department between January 2006 and december 2014. 76 patient medical records were studied. The average age was 50 years (aged 21-89 years) with a male predominance in 57.8% of cases. Clinical symptoms were mainly cough (32.8% of cases), dyspnea (23.7% of cases) and hemoptysis (11.2%). Primary cancers responsible for various pleuro-pulmonary metastases found in our case series were dominated by breast cancers in 27.6% of cases, gastro-intestinal cancers in 15.8% of cases, genital cancers in 9, 2% of cases, sarcomas in 7.8% of cases, renal cancers in 5.2% of cases, bladder cancers in 5.2% of cases, prostate cancers in 3.9% cases, ENT cancers in 3.9% of cases, thyroid cancers in 3.9% of cases, skin cancers in 2.6% of cases and cancers of unknown primary origin in 14.4% of cases respectively. Several radiologic features of pleuro-pulmonary metastases have been found in our case series; they can be isolated or combined. The most common radiologic aspect was multiple pulmonary nodules in 52.6% of cases, followed by pleurisies in 34.2% of cases, diffuse micronodules in 23.6% of cases and a solitary nodule in 3.94% of cases. Secondary pleuropulmonary cancers are frequent. They come in 3rd place after lymph nodes and liver metastases and are found in 30% of autopsies of patients with neoplasia.
Subject(s)
Lung Neoplasms/epidemiology , Neoplasms/pathology , Pleural Neoplasms/epidemiology , Adult , Aged , Aged, 80 and over , Cough/epidemiology , Cough/etiology , Dyspnea/epidemiology , Dyspnea/etiology , Female , Hemoptysis/epidemiology , Hemoptysis/etiology , Humans , Lung Neoplasms/pathology , Lung Neoplasms/secondary , Male , Middle Aged , Multiple Pulmonary Nodules/epidemiology , Neoplasms/epidemiology , Pleural Neoplasms/pathology , Pleural Neoplasms/secondary , Retrospective Studies , Young AdultABSTRACT
Malignant Pleural Mesothelioma (MPM) is the primary malignant tumour of the pleura. It is highly aggressive and linked to the exposure to asbestos fibers. The prognosis of this cancer is bad with a median of survival around 12 months. The diagnosis of pleural mesothelioma is often done at an advanced stage of the disease because of the lack of specific clinical and radiological signs differentiating it from any malignant pleural effusion. The absence of an explicit asbestos exposure is another diagnosis problem. We report the case of a 60-year-old patient without any prior exposure to asbestos who presented for pleural effusion and a nodular thickening of the pleura on the CT scan. The diagnosis of MPM was confirmed after pathology study of the biopsies obtained by video assisted thoracoscopy.
