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Rev Neurol (Paris) ; 149(1): 46-9, 1993.
Article in French | MEDLINE | ID: mdl-8337562

ABSTRACT

A 30 year-old woman developed a postural and rest tremor of the left hand following a right peduncular post-traumatic hematoma. Two years later, positron emission tomography showed a marked decrease in [18F] fluorodopa uptake contrasting with a normal [76Br] bromolisuride uptake in the right striatum. This suggests that: 1) chronic unilateral dopaminergic striatal denervation may occur without persistent D2 dopaminergic receptor upregulation in humans; and 2) symptomatic mesencephalic tremor may be, at least in part, related to dopaminergic striatal denervation.


Subject(s)
Brain Injuries/complications , Cerebral Hemorrhage/complications , Corpus Striatum/physiopathology , Dopamine/physiology , Tomography, Emission-Computed , Tremor/etiology , Adult , Brain Injuries/diagnosis , Cerebral Hemorrhage/diagnosis , Corpus Striatum/diagnostic imaging , Female , Humans , Magnetic Resonance Imaging , Mesencephalon , Tremor/diagnostic imaging
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