1.
Bull Exp Biol Med
; 137(2): 147-9, 2004 Feb.
Article
in English, Russian
| MEDLINE
| ID: mdl-15273760
ABSTRACT
We studied the effects of selective delta-opiate receptor agonists and antagonists on the phosphoinositide pathway in lymphocytes from healthy donors and patients with diabetes mellitus. The test compounds probably play a role in changes in the sensitivity to pharmacological substances binding to delta-opiate receptors during diabetes mellitus.
Subject(s)
Diabetes Mellitus/metabolism , Naltrexone/analogs & derivatives , Phosphatidylinositols/metabolism , Receptors, Opioid, delta/metabolism , Benzylidene Compounds/pharmacology , Diglycerides/metabolism , Humans , In Vitro Techniques , Lymphocytes/drug effects , Lymphocytes/metabolism , Naltrexone/pharmacology , Oligopeptides/pharmacology , Receptors, Opioid, delta/agonists , Receptors, Opioid, delta/antagonists & inhibitors , Signal Transduction/drug effects
2.
Biochemistry (Mosc)
; 64(11): 1279-82, 1999 Nov.
Article
in English
| MEDLINE
| ID: mdl-10611533
ABSTRACT
The in vivo effect of external electrostatic field (200 kV/m for 1 h) on the activity of type A phospholipases and lysophospholipases of erythrocyte and mitochondrial membranes was studied. The electrostatic field exposure activated membrane-associated deacylation of phosphatidylcholine fraction in erythrocyte membranes.
