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J Clin Dent ; 11(2): 53-9, 2000.
Article in English | MEDLINE | ID: mdl-11460284

ABSTRACT

The aim of the present study was to evaluate the effect of a green tea bioflavonoid/zinc ascorbate-containing dentifrice (Natural Antioxidant Toothpaste) on bacterial plaque biofilm accumulation. Plaque biofilms were formed and observed on saliva-conditioned synthetic hydroxyapatite disks (HA) over 4 days. Two test treatments were performed daily over a 4-day experimental period for a total of 8 treatments. Four test dentifrices were evaluated: a 0.1% bioflavonoid/0.2% zinc ascorbate; a non-active control test dentifrice; a 0.075% sanguinarine/2.0% zinc chloride dentifrice; and a 0.3% triclosan dentifrice. The repeated treatment of the HA with the green tea bioflavonoid/zinc ascorbate, the sanguinarine/zinc chloride, or the triclosan dentifrice resulted in significant reductions in total viable plaque biomass when compared to a non-active placebo control dentifrice.


Subject(s)
Ascorbic Acid/therapeutic use , Biofilms/drug effects , Dental Plaque/prevention & control , Dentifrices/therapeutic use , Flavonoids/therapeutic use , Alkaloids/pharmacology , Alkaloids/therapeutic use , Analysis of Variance , Antioxidants/pharmacology , Antioxidants/therapeutic use , Ascorbic Acid/pharmacology , Benzophenanthridines , Complex Mixtures , Dentifrices/pharmacology , Durapatite , Flavonoids/pharmacology , Fluorides , Isoquinolines , Microscopy, Electron, Scanning , Phytotherapy , Pilot Projects , Silicic Acid , Streptococcus oralis/drug effects , Tea/therapeutic use , Toothpastes , Triclosan , Zinc Compounds/therapeutic use
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