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1.
Pak J Pharm Sci ; 31(5): 2005-2009, 2018 Sep.
Article in English | MEDLINE | ID: mdl-30150201

ABSTRACT

Canola oil has been used in the Pakistan for the treatment of various diseases and skin infections. Oil was extracted with n-hexane from the seeds of canola (Brassica napus L.) and was evaluated for free fatty acid value. Four microorganisms namely; Staphylococcus aureus, Staphylococcus epidermidis, Pseudomonas originals, and Klebsiella pneumonia, has known to cause some infections treatable with these oils were investigated. The results showed that all oil shown inhibitory effects against Klebsiella pneumoniae, Staphylococcus epidermidis, and Pseudomonas originals but no inhibitory effects was found against Staphylococcus aureus.


Subject(s)
Anti-Bacterial Agents/pharmacology , Anti-Infective Agents/pharmacology , Brassica napus , Phytochemicals/pharmacology , Rapeseed Oil/pharmacology , Seeds , Anti-Bacterial Agents/chemistry , Anti-Bacterial Agents/isolation & purification , Anti-Infective Agents/chemistry , Anti-Infective Agents/isolation & purification , Chemistry, Physical/methods , Humans , Phytochemicals/chemistry , Phytochemicals/isolation & purification , Rapeseed Oil/chemistry , Rapeseed Oil/isolation & purification , Staphylococcus aureus/drug effects , Staphylococcus aureus/physiology
2.
Pak J Pharm Sci ; 31(4): 1441-1448, 2018 Jul.
Article in English | MEDLINE | ID: mdl-30033432

ABSTRACT

Among known species of 69 Mangifera, Mangifera indica L. is a medicinal plant being used in tropical regions by indigenous people. It has been a main plant species being used in Ayurvedic as well as indigenous medical systems form 4000 years. Components of M. indica are recurrently used as a traditional medicine system to cure numerous ailments. Active constituents are present in stem bark, leaves, heartwood, roots and fruit and have antioxidant, anti-inflammatory, radioprotective, antitumor, immune-modulatory, anti-allergic, anti-diabetic, anti-bone resorption, mono-amine oxidase inhibiting, anti-viral, anti-fungal, anti-bacterial, anti-spasmodic, antidiarrheal, anti-malarial, antiparasitic as well as lipolytic properties. In spite of essential progress in phyto-chemical and medicinal analysis of M. indica, more efforts are needed to explore M. indica active components and their application in pharmaceutical industry. In this review, we focus on recent information about chemical constituents and pharmacological uses of M. indica.


Subject(s)
Mangifera/chemistry , Plant Extracts , Animals , Humans , Medicine, Ayurvedic , Molecular Structure , Plant Extracts/isolation & purification , Plant Extracts/pharmacology , Plant Extracts/therapeutic use , Plants, Medicinal
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