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1.
J Fr Ophtalmol ; 37(7): 548-56, 2014 Sep.
Article in French | MEDLINE | ID: mdl-25085227

ABSTRACT

BACKGROUND AND PURPOSE OF STUDY: The purpose of our study was to assess safety and efficacy of cataract surgery (CS) under topical anesthesia alone, i.e. without pre-anesthetic evaluation and without direct presence of an anesthesiologist. To this end we assessed the incidence of patients' preoperative anxiety, perioperative adverse events and patients' and surgeons' satisfaction. MATERIALS AND METHODS: Patients undergoing CS under topical anesthesia over a one-month period were included. An anesthesiologist and nurse anesthetist were present in the area and could intervene in case of an adverse event. Patients' anxiety was scored using the Amsterdam Preoperative Anxiety & Information Scale (APAIS), and their satisfaction with the Iowa Satisfaction with Anesthesia Scale (ISAS). Surgeons' satisfaction was scored with a VAS from 0 to 10 (0: surgery not possible & 10: excellent surgical conditions). RESULTS AND DISCUSSION: One hundred and twenty-four consecutive patients were included; mean age was 71 (±9.4) years. Mean APAIS I was 6.4/20 (±3.7). Mean APAIS II was 3.1 (±1.8). Mean ISAS score was 5.5/6 (±0.6), indicating high patient satisfaction. Surgeon satisfaction score was 8.9/10 (±1.7). Twenty-three adverse events occurred of which 16 required interventions by the anaesthesiologist or surgeon: 5 supplemental local or regional anaesthesia, 6 iv-analgesia, 5 management of hypertension. CONCLUSION: These preliminary data suggest that a simplified topical anesthesia protocol for ambulatory CS appears to be feasible and safe, as long as an anesthesia team is present in the area to intervene if needed.


Subject(s)
Ambulatory Surgical Procedures , Anesthetics, Local/administration & dosage , Attitude of Health Personnel , Cataract Extraction , Patient Satisfaction , Procaine/analogs & derivatives , Administration, Topical , Adult , Aged , Aged, 80 and over , Anxiety/diagnosis , Female , Humans , Male , Middle Aged , Preoperative Care , Procaine/administration & dosage , Prospective Studies , Surveys and Questionnaires
2.
J Fr Ophtalmol ; 36(8): 683-6, 2013 Oct.
Article in French | MEDLINE | ID: mdl-23896211

ABSTRACT

We report the case of a 31-month-old girl, treated by the ifosfamide-vincristine-actinomycin chemotherapy protocol for vaginal rhabdomyosarcoma, who developed a unilateral left ptosis on day 36 of chemotherapy, i.e. 7 days after the fifth vincristine dose (1.5mg/m(2) or 0.90 mg). The cumulative vincristine dose was thus 4.50mg. The remainder of the neurological and systemic examinations were unremarkable. Laboratory testing and thoracic-cervical-cranial CT were normal. Other causes of ptosis were excluded. The ptosis decreased a few days after the infusion of vincristine and re-increased just after a new dose. It finally resolved upon lowering the dose of vincristine. According to our observations, the role of vincristine in the pathogenesis of this ptosis appears "likely". In such cases, maintenance of treatment is possible with adjustment of vincristine doses, but requires regular follow-up.


Subject(s)
Blepharoptosis/chemically induced , Blepharoptosis/diagnosis , Vincristine/adverse effects , Antineoplastic Combined Chemotherapy Protocols/therapeutic use , Child, Preschool , Dactinomycin/administration & dosage , Female , Humans , Ifosfamide/administration & dosage , Rhabdomyosarcoma/drug therapy , Vaginal Neoplasms/drug therapy , Vincristine/administration & dosage
3.
J Fr Ophtalmol ; 35(2): 117-20, 2012 Feb.
Article in French | MEDLINE | ID: mdl-22261387

ABSTRACT

Conjunctival synthetic fiber granulomas, or "Teddy bear granulomas", are rare granulomatous responses to synthetic fabric fibers. We report the case of a 3-year-old boy with no prior infectious or traumatic history, brought in by his parents for an incidentally discovered conjunctival growth in his right eye. Slit lamp examination revealed a 10-mm growth in the inferior fornix surrounding a small greyish foreign body. Surgical excision and histopathology revealed granulomatous inflammatory cell response with foreign body giant cells surrounding exogenous material. This foreign material was birefringent in polarized light, very suggestive of synthetic fabric fibers, which permitted the diagnosis of Teddy bear granuloma. Synthetic fiber granulomas present in children as unilateral, more or less inflammatory growths in the inferior conjunctival fornix. Surgical excision with histopathology makes the diagnosis and effects the cure.


Subject(s)
Conjunctival Diseases/etiology , Eye Foreign Bodies/complications , Granuloma, Foreign-Body/etiology , Play and Playthings , Textiles/adverse effects , Child, Preschool , Conjunctival Diseases/diagnosis , Eye Foreign Bodies/diagnosis , Granuloma, Foreign-Body/diagnosis , Humans , Male , Play and Playthings/injuries , Rare Diseases/diagnosis , Rare Diseases/etiology
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