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Tissue Antigens ; 63(3): 282-3, 2004 Mar.
Article in English | MEDLINE | ID: mdl-14989721

ABSTRACT

We report here the identification of a novel DRB1*11 allele, DRB1*1144, identified during sequence-based HLA-DRB1 typing. Molecular cloning and direct sequencing confirmed that the new allele is identical to DRB1*110401 at exon 2, except for a single nucleotide substitution (GTG-->GCG) changing codon 38 from Valine to Alanine.


Subject(s)
Alleles , HLA-DR Antigens/genetics , Amino Acid Substitution/genetics , Base Sequence , Cloning, Organism , HLA-DRB1 Chains , Humans , Molecular Sequence Data , Polymorphism, Single Nucleotide , Sequence Alignment
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