[Bupivacaine and the humoral component of the immunlogical secondary response (author's transl)]. / Bupivacain und die humorale Komponente der immunologischen Sekundärantwort.

Using the Jerne-Plaque-Technique, as modified by Cunningham, the influence of the local anaesthetic bupivacaine (over-all dose 200 mg/kg weight) on the immunological secondary response of the mice was tested. Plasma cells producing IgM as well as those producing IgG could not be shown to be significantly susceptible to suppression by bupivacaine.

[Acute arterial hypotension by sodium-nitroprusside and intraocular tension (author's transl)]. / Akute arterielle Hypotonie durch Natrium-Nitroprussid und intraoculare Tension.

The relationship between intraocular pressure by short-term intravenous Sodium-Nitroprusside induced arterial hypotension in intubation-anaesthesia was studied in 19 cats. A reduction of the blood pressure from an average of 168 mm Hg to 89 mm Hg (that is 47%) was followed by a clearly reproducible reduction of intraocular pressure from an average of 22 mm Hg to 10 mm Hg (that is 55%). These findings for the "closed" eye are a prerequisite for the understanding of the effects of sodium-nitroprusside in the "open" eye.

[Controlled hypotension in difficult intraocular anterior segment surgery (author's transl)]. / Kontrollierte Hypotension bei schwierigen intraokularen Eingriffen.

During anaesthesia controlled hypotension -- induced by sodium nitroprusside -- was used in 60 patients undergoing intraocular anterior segment surgery. The advantages of this procedure are that the iris-lens diaphragma and the vitreous body have a lesser tendency to protrude than with other techniques despite even more superficial anaesthesia.

[Controlled hypotension by sodium-nitroprusside in general anaesthesia for difficult intraocular surgery (preliminary report) (author's transl)]. / Kontrollierte Hypotension durch Natrium-Nitroprussid bei der Allgemeinnarkose für schwierige intraokulare Eingriffe (Vorläufige Mitteilung).

General anaesthesia was performed in 75 patients with difficult intraocular procedures in which the standard relaxation and hyperventilation was supplemented by controlled short-term hypotension by sodium-nitroprusside. This resulted in a significant decrease of the "vis a tergo"--e.g. the threatening prolaps of intraocular tissue. Preliminary experience revealed that intraoperative complications in these difficult situations are reduced. As this facilitates also the task of the anaesthesist this broadens our indications for complex intraocular surgery particularly in younger patients.