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2.
Stat Methods Med Res ; 30(1): 331-346, 2021 01.
Article in English | MEDLINE | ID: mdl-32940148

ABSTRACT

Human body composition is made up of mutually exclusive and exhaustive parts (e.g. %truncal fat, %non-truncal fat and %fat-free mass) which are constrained to sum to the same total (100%). In statistical analyses, individual parts of body composition (e.g. %truncal fat or %fat-free mass) have traditionally been used as proxies for body composition, and have been linked with a range of health outcomes. But analysis of individual parts omits information about the other parts, which are intrinsically co-dependent because of the constant sum constraint of 100%. Further, body mass may be associated with health outcomes. We describe a statistical approach for body composition based on compositional data analysis. The body composition data are expressed as logratios to allow relative information about all the compositional parts to be explored simultaneously in relation to health outcomes. We describe a recent extension to the logratio approach to compositional data analysis which allows absolute information about the total of the compositional parts (body mass) to be considered alongside relative information about body composition. The statistical approach is illustrated by an example that explores the relationships between adults' body composition, body mass and bone strength.


Subject(s)
Body Composition , Data Analysis , Adult , Humans
3.
Pediatr Obes ; 13(11): 744-751, 2018 11.
Article in English | MEDLINE | ID: mdl-30280513

ABSTRACT

BACKGROUND: The PEACH™ randomized controlled trial measured changes to children's food and activity behaviours following participation in a weight management programme. We have previously reported a 10% reduction in body mass index z-score at intervention end (6-month post-baseline) that was maintained to 24 months with no further intervention for the full study sample. OBJECTIVES: The objective of the study is to report changes in food and activity outcomes in the full sample at (i) the end of the 6-month intervention and (ii) 24-month post-baseline (18-month post-intervention). METHODS: Changes in dietary and activity outcomes were assessed over time (baseline: n = 169, 8.1 ± 1.2 years, body mass index z-score 2.72 ± 0.62). Dietary intake was assessed using the Child Dietary Questionnaire, and times spent active and sedentary were assessed using a study-specific questionnaire. Linear mixed models were used. RESULTS: There were significant time effects for all Child Dietary Questionnaire scores and activity and sedentary behaviours in the expected direction. Significant sex effects were observed for fruit and vegetable and sweetened beverages scores and for time spent in small screen-based activity. CONCLUSIONS: This is one of few child weight management studies to report short-term and long-term behaviour outcomes. It demonstrates that an intervention promoting food and activity behaviours consistent with guidelines can achieve modest changes, mediating improvements in relative weight.


Subject(s)
Child Behavior/physiology , Feeding Behavior/physiology , Health Promotion/methods , Healthy Lifestyle/physiology , Weight Reduction Programs/methods , Australia , Body Mass Index , Body Weight , Child , Child, Preschool , Diet , Family , Female , Humans , Male , Program Evaluation/methods , Surveys and Questionnaires
4.
Public Health ; 147: 20-29, 2017 Jun.
Article in English | MEDLINE | ID: mdl-28404492

ABSTRACT

OBJECTIVES: Overweight/obesity is a problem faced by both high- and low- and middle-income countries. This review aimed to report published data on the prevalence of overweight and obesity in Indonesian children, adolescents, and adults, along with the associated risk factors. STUDY DESIGN: Literature review. METHODS: We conducted a literature search for articles published in English (through Medline via OvidSP, Scopus, Global Health via OvidSP and Web of Science electronic databases) and Indonesian languages (several websites, direct contact with Indonesian public health researchers, practitioners and Ministry of Health staff) from earliest to March 2016. We screened the results and ensured the quality of included studies with Loney's tools for critically appraising prevalence or incidence studies. RESULTS: We included 17 papers on the topic which were available in full text and passed the critical appraisal process. The prevalence of overweight/obesity has increased over the past two decades in Indonesian children, adolescents and adults. Prevalence rates are higher in boys than girls among children, but higher in females in the adolescent and adult age groups. The prevalence of overweight/obesity is also higher in those living in urban areas and with higher income or education. CONCLUSIONS: Overweight/obesity is a serious public health problem in Indonesia with a continuing increase in its prevalence. Interventions at the household level and beyond are needed to successfully lower the prevalence of overweight/obesity in the country.


Subject(s)
Obesity/epidemiology , Overweight/epidemiology , Humans , Indonesia/epidemiology , Prevalence , Risk Factors
5.
Eur J Clin Nutr ; 71(5): 646-651, 2017 05.
Article in English | MEDLINE | ID: mdl-28225054

ABSTRACT

BACKGROUND/OBJECTIVES: Adolescents have unique nutrient requirements due to rapid growth and development. High rates of obesity in adolescents require a variety of diet interventions to achieve weight loss under clinical supervision. The aim of this study is to examine the nutritional adequacy of energy-restricted diets for adolescents. SUBJECTS/METHODS: Three popular diets were modelled for 7 days and assessed by comparing the nutrient profile to the Australian Nutrient Reference Values. Three diets were: (1) a standard energy restricted diet based on current dietary guidelines; (2) a modified carbohydrate diet; and (3) a modified alternate day fasting diet. RESULTS: Initial modelling revealed limiting nutrients (that is, not meeting the recommended intakes) across the diets. Subsequent modelling was required to achieve nutritional adequacy for all three diets. The dietary guidelines diet design met most nutrient targets except essential fatty acids before subsequent modelling, however this diet also provided the highest energy (8.8 vs 8.0 MJ and 6.8 MJ for the modified carbohydrate and modified alternate day fasting diet, respectively). CONCLUSIONS: Energy-restricted diets need careful consideration to meet nutritional requirements of adolescents. A variety of eating patterns can be adapted to achieve nutritional adequacy and energy restriction, however health practitioners need to consider adequacy when prescribing diet interventions for weight loss during adolescence.


Subject(s)
Diet , Dietetics , Nutrition Assessment , Nutritional Requirements , Obesity/diet therapy , Overweight/diet therapy , Adolescent , Australia , Caloric Restriction , Dietary Carbohydrates/administration & dosage , Dietary Fats/administration & dosage , Dietary Fiber/administration & dosage , Dietary Proteins/administration & dosage , Fasting , Female , Humans , Male , Micronutrients/administration & dosage , Nutrition Policy , Weight Loss
6.
Intern Med J ; 47(2): 162-169, 2017 Feb.
Article in English | MEDLINE | ID: mdl-27761992

ABSTRACT

BACKGROUND: Few studies have focused on the prevalence of obesity and hypertension among young people (ages 15-24). AIM: To characterise the prevalence of obesity and systolic hypertension in young people aged 15-24 years across Australia. METHODS: Using data from the 2011-2012 Australian Health Survey, a national cross-sectional population-based survey, we included 2163 young people aged 15-24 years. Risk factors were estimated using multinomial logistic regression. RESULTS: The prevalence of obesity increased from 8% to 15% through the ages of 15-24 among males, but the prevalence of overweight and obesity were both 14% for females across all age groups. Low levels of physical activity were a strong risk factor for obesity for both males (odds ratio (OR) 5.95, 95% confidence intervals (CI)1.83-19.36) and females (OR 3.20 95% CI 0.69-14.87). Low socioeconomic status was associated with obesity among females only (first quintile OR 4.65, 95% CI 1.97-10.99). Although the prevalence of hypertension was low (4% males, 3% females), the prevalence of high normal blood pressure was substantial, especially among males (28% males, 14% females). CONCLUSIONS: Overweight, obesity and high normal blood pressure were highly prevalent among Australian young people. Low levels of physical activity were identified as a risk factor for obesity for both male and females. Programmes targeting physical activity participation may need to be tailored differently for males and females, with a focus on females during early adolescence but early adult life for males.


Subject(s)
Hypertension/epidemiology , Obesity/epidemiology , Adolescent , Age Distribution , Australia/epidemiology , Blood Pressure , Cross-Sectional Studies , Exercise , Female , Health Surveys , Humans , Logistic Models , Male , Odds Ratio , Risk Factors , Sex Distribution , Young Adult
7.
Eur J Nutr ; 56(7): 2407-2414, 2017 Oct.
Article in English | MEDLINE | ID: mdl-27475431

ABSTRACT

PURPOSE: Zinc is essential for normal growth and metabolism. We aimed to characterise the total and bioavailable dietary zinc intake and plasma zinc concentrations in healthy children, longitudinally, and to examine the association between plasma zinc concentrations, dietary zinc intake and cardiometabolic markers in the same cohort. METHODS: A secondary data analysis of a prospective cohort study, the Nepean Longitudinal Study, which followed an Australian birth cohort at ages 8 (n = 436) and 15 years (n = 290) collecting dietary, anthropometry and biochemistry data (plasma zinc, fasting glucose, insulin and lipid profile). Diet was assessed by a 3-day food record and a food frequency questionnaire at 8 and 15 years, respectively. Zinc bioavailability was determined by the phytate/zinc molar ratio. RESULTS: At 8 years, the median zinc intake was 7.84 mg (interquartile range 6.57-9.35) for boys and 7.06 mg (5.98-8.30) for girls. Three of 345 children reported inadequate absorbable zinc intake, and none reported inadequate total zinc intake. At 15 years, median zinc intake was 11.8 mg (9.41-14.8) for boys and 8.54 mg (6.76-10.7) for girls. The prevalence of inadequate intakes of absorbable zinc and total zinc was 19 and 29 %, respectively. Plasma zinc concentration was not correlated with dietary zinc intake, adiposity nor lipids at either time point, but it was inversely correlated with fasting glucose at 8 year and with insulin at 15 years. CONCLUSIONS: Australian children had an overall adequate zinc status. However, adolescents who reported suboptimal dietary zinc intakes were more likely to have raised insulin concentrations.


Subject(s)
Diet , Zinc/administration & dosage , Zinc/blood , Adolescent , Australia , Biomarkers/blood , Blood Glucose/metabolism , Body Composition , Body Mass Index , Cardiovascular Diseases/blood , Child , Cholesterol/blood , Dietary Carbohydrates/administration & dosage , Dietary Fats/administration & dosage , Dietary Fiber/administration & dosage , Dietary Proteins/administration & dosage , Female , Humans , Insulin/blood , Longitudinal Studies , Male , Metabolic Syndrome/blood , Micronutrients/administration & dosage , Micronutrients/blood , Nutritional Requirements , Nutritional Status , Phytic Acid/administration & dosage , Phytic Acid/blood , Prospective Studies , Risk Factors , Triglycerides/blood
8.
Int J Obes (Lond) ; 40(7): 1089-95, 2016 07.
Article in English | MEDLINE | ID: mdl-27121249

ABSTRACT

BACKGROUND: Adult Aboriginal Australians have 1.5-fold higher risk of obesity, but the trajectory of body mass index (BMI) through childhood and adolescence and the contribution of socio-economic factors remain unclear. Our objective was to determine the changes in BMI in Australian Aboriginal children relative to non-Aboriginal children as they move through adolescence into young adulthood, and to identify risk factors for higher BMI. METHODS: A prospective cohort study of Aboriginal and non-Aboriginal school children commenced in 2002 across 15 different screening areas across urban, regional and remote New South Wales, Australia. Socio-economic status was recorded at study enrolment and participants' BMI was measured every 2 years. We fitted a series of mixed linear regression models adjusting for age, birth weight and socio-economic status for boys and girls. RESULTS: In all, 3418 (1949 Aboriginal) participants were screened over a total of 11 387 participant years of follow-up. The prevalence of obesity was higher among Aboriginal children from mean age 11 years at baseline (11.6 vs 7.6%) to 16 years at 8 years follow-up (18.6 vs 12.3%). The mean BMI increased with age and was significantly higher among Aboriginal girls compared with non-Aboriginal girls (P<0.01). Girls born of low birth weight had a lower BMI than girls born of normal birth weight (P<0.001). Socio-economic status and low birth weight had a differential effect on BMI for Aboriginal boys compared with non-Aboriginal boys (P for interaction=0.01). Aboriginal boys of highest socio-economic status, unlike those of lower socio-economic status, had a higher BMI compared with non-Aboriginal boys. Non-Aboriginal boys of low birth weight were heavier than Aboriginal boys. CONCLUSIONS: Socio-economic status and birth weight have differential effects on BMI among Aboriginal boys, and Aboriginal girls had a higher mean BMI than non-Aboriginal girls through childhood and adolescence. Intervention programs need to recognise the differential risk for obesity for Aboriginal and non-Aboriginal boys and girls to maximise their impact.


Subject(s)
Birth Weight , Body Mass Index , Native Hawaiian or Other Pacific Islander , Sex Characteristics , Socioeconomic Factors , Adolescent , Child , Female , Health Education/organization & administration , Health Knowledge, Attitudes, Practice , Humans , Male , New South Wales/epidemiology , New South Wales/ethnology , Overweight/epidemiology , Pediatric Obesity/ethnology , Pediatric Obesity/prevention & control , Prevalence , Prospective Studies , Risk Factors , Thinness/epidemiology
9.
Obes Rev ; 17(4): 377-85, 2016 Apr.
Article in English | MEDLINE | ID: mdl-26864566

ABSTRACT

The goal of this study was to understand research trends and collaboration patterns together with scholarly impact within the domain of global obesity research. We developed and analysed bibliographic affiliation data collected from 117,340 research articles indexed in Scopus database on the topic of obesity and published from 1993-2012. We found steady growth and an exponential increase of publication numbers. Research output in global obesity research roughly doubled each 5 years, with almost 80% of the publications and authors from the second decade (2003-2012). The highest publication output was from the USA - 42% of publications had at least one author from the USA. Many US institutions also ranked highly in terms of research output and collaboration. Fifteen of the top-20 institutions in terms of publication output were from the USA; however, several European and Japanese research institutions ranked more highly in terms of average citations per paper. The majority of obesity research and collaboration has been confined to developed countries although developing countries have showed higher growth in recent times, e.g. the publication ratio between 2003-2012 and 1993-2002 for developing regions was much higher than that of developed regions (9:1 vs. 4:1). We also identified around 42 broad disciplines from authors' affiliation data, and these showed strong collaboration between them. Overall, this study provides one of the most comprehensive longitudinal bibliometric analyses of obesity research. This should help in understanding research trends, spatial density, collaboration patterns and the complex multi-disciplinary nature of research in the obesity domain.


Subject(s)
Obesity , Bibliometrics , Data Mining , Humans
10.
Pediatr Obes ; 11(2): 158-60, 2016 Apr.
Article in English | MEDLINE | ID: mdl-26261017

ABSTRACT

BACKGROUND: Children's exposure to unhealthy food marketing is a contributor to poor diets and weight gain. Television food advertising, in particular, has been the focus of research and policy discussions. OBJECTIVES: We aimed to quantify the specific impact of television advertising, as distinct from television viewing generally, on children's usual diet. Methods Four hundred seventeen Australian children aged 10-16 participated in an online survey, which assessed television viewing habits and consumption of 12 frequently advertised unhealthy foods/drinks. Consumption of these foods/drinks was dichotomized (less weekly, weekly or more) and summed (1 point for each item consumed weekly or more) to give cumulative consumption scores. RESULTS: After adjusting for age and socioeconomic status, there was strong evidence of an increase in unhealthy food score (P < 0.001), drink score (P = 0.002) and food/drink combined score (P < 0.001), with increasing commercial television viewing. CONCLUSIONS: The link between television viewing and poor diet was strongest for children who watched the most commercial television, and those who were actually exposed to advertisements embedded within programs. This association between advertisement exposure and poor diet emphasizes the need for public policy intervention to reduce children's food advertising exposures.


Subject(s)
Advertising , Feeding Behavior/psychology , Marketing/statistics & numerical data , Television , Australia , Child , Child, Preschool , Female , Humans , Male , Social Class , Surveys and Questionnaires , Television/statistics & numerical data
11.
Neth Heart J ; 23(7-8): 402-4, 2015 Jul.
Article in English | MEDLINE | ID: mdl-26031635

ABSTRACT

The purpose of this case report is to describe a rare case of a patient with a phaeochromocytoma with several cardiovascular complications, which can be attributed to the tumour. Detection of a phaeochromocytoma sometimes needs a 'Sherlock Holmes spirit' or simply time.

12.
Nutr Metab Cardiovasc Dis ; 24(11): 1221-7, 2014 Nov.
Article in English | MEDLINE | ID: mdl-24996501

ABSTRACT

BACKGROUND AND AIMS: The relationship between dairy food consumption and dietary calcium intake, and vascular risk factors during adolescence remains unclear. We aimed to prospectively assess whether dairy food consumption (milk, cheese, yoghurt) is associated with blood pressure (BP) and retinal microvascular signs among adolescents. METHODS AND RESULTS: As many as 2353 and 1216 participants aged 12 and 17, respectively, were examined. Longitudinal analyses involved 888 subjects with complete baseline and follow-up data. Dairy consumption was assessed from validated semi-quantitative food frequency questionnaires. BP information was collected and retinal vessel caliber was quantified from digital photographs using computer software. In girls, after multivariable adjustment, each serve/day increase in total dairy intake was concurrently associated with 1.04 (p = 0.03) and 1.10 mm Hg (p = 0.02) decreases in mean diastolic and arterial BP, respectively. Also in girls, each serve/day increase in cheese intake over 5 years was concurrently related to 7.18 (p = 0.001), 5.28 (p = 0.002) and 5.79 mm Hg (p = 0.001) decrease in mean systolic, diastolic and arterial BP, respectively. Among girls, each 100 mg/day increase in dietary calcium intake was associated with a concurrent 0.5 (p = 0.01) and 0.3 mm Hg (p = 0.02) decrease in mean systolic and arterial BP, respectively. Cross-sectionally, adolescents in the highest versus lowest tertile of yoghurt intake had ∼ 1.3 µm wider retinal arterioles (p = 0.05) and ∼ 2.0 µm narrower venules (p = 0.04). CONCLUSIONS: Consumption of dairy products, particularly cheese, could have a beneficial effect on BP, particularly among girls.


Subject(s)
Blood Pressure , Calcium, Dietary/administration & dosage , Dairy Products , Diet , Microcirculation , Retinal Vessels/physiology , Adolescent , Child , Cross-Sectional Studies , Female , Humans , Linear Models , Male , Multivariate Analysis , Nutrition Assessment , Prospective Studies , Risk Factors , Surveys and Questionnaires
13.
J Hum Hypertens ; 28(12): 721-5, 2014 Dec.
Article in English | MEDLINE | ID: mdl-24573132

ABSTRACT

We investigated the cross-sectional association between parental history of hypertension and dietary intakes among early adolescent schoolchildren. A total of 1845 participants aged 12 years had complete data on diet and parental medical history, and thus they were included in the final analyses. Dietary data were assessed from validated semi-quantitative food-frequency questionnaires. Parents completed questionnaires about their medical conditions. Cases where the biological mother and/or father had hypertension were classified as positive parental history of hypertension. After multivariable adjustment, participants with positive versus negative parental history of hypertension had 33% greater likelihood of consuming soft drinks ⩾1 per week. Boys with a parental history versus boys without a parental history of hypertension consumed more energy-dense, nutrient-poor foods: 379.4 g per day and 318.0 g per day, respectively, P=0.02. Girls with a positive versus a negative parental history consumed more vegetables: 164.1 versus 142.6 g per day, P=0.01. Significant associations were not observed between those with and those without a positive parental history in mean dietary intakes of carbohydrates, fats, sugars and sodium. Children with a positive parental history of hypertension were 67% more likely to simultaneously engage in three unhealthy lifestyle behaviors (excessive recreational screen viewing, high consumption of snacks and and high consumption of soft drinks). Parental hypertension was associated with unhealthy dietary behaviors among offspring, including higher consumption of soft drinks and energy-dense, nutrient-poor foods.


Subject(s)
Diet , Hypertension/etiology , Carbonated Beverages , Child , Cluster Analysis , Cross-Sectional Studies , Female , Humans , Hypertension/genetics , Life Style , Male , Risk Factors , Surveys and Questionnaires , Vegetables
14.
Pediatr Obes ; 9(2): e47-57, 2014 Apr.
Article in English | MEDLINE | ID: mdl-23630014

ABSTRACT

OBJECTIVES: To assess pre-adolescent children's responses to common child-oriented front-of-pack food promotions. METHODS: Between-subjects, web-based experiment with four front-of-pack promotion conditions on energy-dense and nutrient-poor (EDNP) foods: no promotion [control]; nutrient content claims; sports celebrity endorsements (male athletes) and premium offers. Participants were 1302 grade 5 and 6 children (mean age 11 years) from Melbourne, Australia. Participants chose their preferred product from a randomly assigned EDNP food pack and comparable healthier food pack then completed detailed product ratings. Child-oriented pack designs with colourful, cartooned graphics, fonts and promotions were used. RESULTS: Compared to the control condition, children were more likely to choose EDNP products featuring nutrient content claims (both genders) and sports celebrity endorsements (boys only). Perceptions of nutritional content were enhanced by nutrient content claims. Effects of promotions on some product ratings (but not choice) were negated when children referred to the nutrition information panel. Premium offers did not enhance children's product ratings or choice. CONCLUSIONS: Nutrient content claims and sports celebrity endorsements influence pre-adolescent children's preferences towards EDNP food products displaying them. Policy interventions to reduce the impact of unhealthy food marketing to children should limit the use of these promotions.


Subject(s)
Athletes , Choice Behavior , Famous Persons , Food Industry/methods , Food Labeling , Food Preferences , Nutritive Value , Adolescent , Advertising , Child , Child Nutritional Physiological Phenomena , Child, Preschool , Female , Humans , Male , Marketing , Sex Distribution , Surveys and Questionnaires
15.
Int J Obes (Lond) ; 38(4): 475-9, 2014 Apr.
Article in English | MEDLINE | ID: mdl-24247372

ABSTRACT

Transition in pediatric health care involves the purposeful, planned movement of patients from pediatric to adult services. Following the significant increases in long-term survival of chronic childhood diseases in the 1980s, transition has taken on an increasing importance in the management of these chronic diseases. In Australia, there is a conspicuous lack of programs/guidelines for transitioning adolescents with obesity. The authors sought to determine if this is an international phenomenon that should be addressed. This study aimed to identify what formal transition services or guidelines exist internationally for adolescents with overweight/obesity. Two systematic reviews of the published and 'gray' literature were implemented via searches of relevant databases, search engines and websites. The primary review eligibility criteria were documents published between 1982 and 2012 including any aspect of transitioning adolescents with overweight/obesity from pediatric to adult weight management services. The secondary review included current clinical practice guidelines/statements on pediatric obesity management published between 1992 and 2012, and transition recommendations contained within. Non-English language documents were excluded. Relevant text from eligible documents was systematically identified and extracted, and a qualitative synthesis of the data was prepared. Overall, 2272 unique records were identified from the literature searches. Three eligible articles were identified by the primary review. The secondary review identified 24 eligible guidelines/statements. In total, six of the identified documents contained information on transition in adolescent obesity-the most detailed documents provided only a brief statement recommending that transition from pediatric to adult weight management services should take place. In conclusion, internationally there is an absence of published intervention programs/policies, and brevity of clinical guidance and expert opinion, on the transition of adolescents with obesity making this a priority research area. Consideration is given to the reasons why transition in adolescent obesity is a neglected topic.


Subject(s)
Adolescent Health Services , Pediatric Obesity/therapy , Transition to Adult Care , Adolescent , Adolescent Behavior , Australia/epidemiology , Chronic Disease , Evidence-Based Medicine , Female , Humans , Interdisciplinary Communication , Male , Pediatric Obesity/epidemiology , Practice Guidelines as Topic , Transition to Adult Care/organization & administration
16.
Pediatr Obes ; 9(5): 327-38, 2014 Oct.
Article in English | MEDLINE | ID: mdl-23894119

ABSTRACT

OBJECTIVE: To examine the associations between body mass index (BMI) and waist-to-height ratio (WHtR) measured in childhood and adolescence and cardiometabolic risk factors in adolescence. METHODS: Secondary data analysis of the Avon Longitudinal Study of Parents and Children, a population based cohort. Data from 2858 adolescents aged 15.5 (standard deviation 0.4) years and 2710 of these participants as children aged 7-9 years were used in this analysis. Outcome measures were cardiometabolic risk factors, including triglycerides, low density lipoprotein cholesterol, high density lipoprotein cholesterol, insulin, glucose and blood pressure at 15 years of age. RESULTS: Both BMI and WHtR measured at ages 7-9 years and at age 15 years were associated with cardiometabolic risk factors in adolescents. A WHtR ≥0.5 at 7-9 years increased the odds by 4.6 [95% confidence interval 2.6 to 8.1] for males and 1.6 [0.7 to 3.9] for females of having three or more cardiometabolic risk factors in adolescence. Cross-sectional analysis indicated that adolescents who had a WHtR ≥0.5, the odds ratio of having three or more cardiometabolic risk factors was 6.8 [4.4 to 10.6] for males and 3.8 [2.3 to 6.3] for females. The WHtR cut-point was highly specific in identifying cardiometabolic risk co-occurrence in male children and adolescents as well as female children (90 to 95%), but had poor sensitivity (17 to 53%). Similar associations were observed when BMI was used to define excess adiposity. CONCLUSIONS: WHtR is a simple alternative to age and sex adjusted BMI for assessing cardiometabolic risk in adolescents.


Subject(s)
Cardiovascular Diseases/epidemiology , Metabolic Syndrome/epidemiology , Obesity/epidemiology , Adolescent , Body Mass Index , Cardiovascular Diseases/blood , Cardiovascular Diseases/physiopathology , Cross-Sectional Studies , Female , Humans , Male , Metabolic Syndrome/blood , Metabolic Syndrome/physiopathology , Obesity/blood , Obesity/physiopathology , Odds Ratio , Prospective Studies , Risk Assessment , Risk Factors , Waist-Height Ratio
17.
Obes Rev ; 14 Suppl 1: 59-69, 2013 Oct.
Article in English | MEDLINE | ID: mdl-24074211

ABSTRACT

Food and non-alcoholic beverage marketing is recognized as an important factor influencing food choices related to non-communicable diseases. The monitoring of populations' exposure to food and non-alcoholic beverage promotions, and the content of these promotions, is necessary to generate evidence to understand the extent of the problem, and to determine appropriate and effective policy responses. A review of studies measuring the nature and extent of exposure to food promotions was conducted to identify approaches to monitoring food promotions via dominant media platforms. A step-wise approach, comprising 'minimal', 'expanded' and 'optimal' monitoring activities, was designed. This approach can be used to assess the frequency and level of exposure of population groups (especially children) to food promotions, the persuasive power of techniques used in promotional communications (power of promotions) and the nutritional composition of promoted food products. Detailed procedures for data sampling, data collection and data analysis for a range of media types are presented, as well as quantifiable measurement indicators for assessing exposure to and power of food and non-alcoholic beverage promotions. The proposed framework supports the development of a consistent system for monitoring food and non-alcoholic beverage promotions for comparison between countries and over time.


Subject(s)
Child Behavior , Food Industry , Food Labeling , Health Promotion , Marketing , Obesity/prevention & control , Adolescent , Beverages , Child , Child Nutrition Sciences , Child, Preschool , Data Collection , Feeding Behavior , Female , Food , Food Industry/legislation & jurisprudence , Food Labeling/legislation & jurisprudence , Humans , Male , Marketing/legislation & jurisprudence , Mass Media , Nutrition Assessment , Obesity/epidemiology
18.
Int J Cardiol ; 168(3): 2487-93, 2013 Oct 03.
Article in English | MEDLINE | ID: mdl-23602867

ABSTRACT

BACKGROUND: Heart failure (HF) is a serious complication and often the cause of death in adults with congenital heart disease (CHD). Therefore, our aims were to determine the frequency of HF-admissions, and to assess risk factors of first HF-admission and of mortality after first HF-admission in adults with CHD. METHODS: The Dutch CONCOR registry was linked to the Hospital Discharge Registry and National Mortality Registry to obtain data on HF-admissions and mortality. Risk factors for both HF-admission and mortality were assessed using Cox regression models. RESULTS: Of 10,808 adult patients (49% male), 274 (2.5%) were admitted for HF during a median follow-up period of 21 years. The incidence of first HF-admission was 1.2 per 1000 patient-years, but the incidence of HF itself will be higher. Main defect, multiple defects, and surgical interventions in childhood were identified as independent risk factors of HF-admission. Patients admitted for HF had a five-fold higher risk of mortality than patients not admitted (hazard ratio (HR)=5.3; 95% confidence interval 4.2-6.9). One- and three-year mortality after first HF-admission were 24% and 35% respectively. Independent risk factors for three-year mortality after first HF-admission were male gender, pacemaker implantation, admission duration, non-cardiac medication use and high serum creatinine. CONCLUSIONS: The incidence of HF-admission in adults with CHD is 1.2 per 1000 patient-years. Mortality risk is substantially increased after HF-admission, which emphasises the importance to identify patients at high risk of HF-admission. These patients might benefit from closer follow-up and earlier medical interventions. The presented risk factors may facilitate surveillance.


Subject(s)
Heart Defects, Congenital/complications , Heart Failure/etiology , Heart Failure/mortality , Patient Admission/statistics & numerical data , Adolescent , Adult , Aged , Aged, 80 and over , Female , Humans , Male , Middle Aged , Prognosis , Risk Assessment , Risk Factors , Young Adult
19.
Int J Obes (Lond) ; 37(3): 468-72, 2013 Mar.
Article in English | MEDLINE | ID: mdl-22584456

ABSTRACT

This paper reports the final 24-month outcomes of a randomized controlled trial evaluating the effect of additional therapeutic contact (ATC) as an adjunct to a community-based weight-management program for overweight and obese 13-16-year-olds. ATC involved telephone coaching or short-message-service and/or email communication once per fortnight. Adolescents were randomized to receive the Loozit group program-a two-phase behavioral lifestyle intervention with (n=73), or without (n=78), ATC in Phase 2. Adolescents/parents separately attended seven weekly group sessions (Phase 1), followed by quarterly adolescent sessions (Phase 2). Assessor-blinded, 24-month changes in anthropometry and metabolic health included primary outcomes body mass index (BMI) z-score and waist:height ratio (WHtR). Secondary outcomes were self-reported psychosocial and lifestyle changes. By 24 months, 17 adolescents had formally withdrawn. Relative to the Loozit program alone, ATC largely had no impact on outcomes. Secondary pre-post assessment of the Loozit group program showed mean (95% CI) reductions in BMI z-score (-0.13 (-0.20, -0.06)) and WHtR (-0.02 (-0.03, -0.01)) in both arms, with several metabolic and psychosocial improvements. Adjunctive ATC did not provide further benefits to the Loozit group program. We recommend that further work is needed to optimize technological support for adolescents in weight-loss maintenance. Australian New Zealand Clinical Trials Registry Number ACTRNO12606000175572.


Subject(s)
Behavior Therapy/methods , Directive Counseling/methods , Obesity/therapy , Telephone , Weight Reduction Programs/methods , Adolescent , Adolescent Behavior , Adolescent Health Services , Australia/epidemiology , Body Mass Index , Female , Humans , Life Style , Male , Obesity/epidemiology , Obesity/psychology , Text Messaging , Weight Loss
20.
J Hum Hypertens ; 27(2): 79-84, 2013 Feb.
Article in English | MEDLINE | ID: mdl-22534831

ABSTRACT

We aimed to investigate the association between birth parameters with blood pressure (BP) among preschool- and school-aged children. Two separate childhood datasets were used: (1) 1295 children aged 3-6 years were examined during 2007-2009; and (2) 1741 and 2353 children aged 6 and 12 years, respectively, were examined during 2004-2006. Birth parameter data were obtained from parental records. BP was measured using standard protocols. Among 6-year-old children, each 1 kg decrease in birth weight was associated with a 1.33- and 1.20-mm Hg higher systolic and diastolic BP, respectively, after multivariable adjustment. In 6-year-old children, a decrease of 1 week in gestational age was independently associated with a 0.33- and 0.37-mm Hg higher systolic and diastolic BP, respectively. Six-year-old children in the low birth weight category (≤ 2499 g) versus those in the normal/high birth weight category (≥ 2500 g) had significantly higher systolic BP (P<0.0001). Girls in the low birth weight category versus those in the normal/high weight category had higher systolic BP (P=0.02). Significant associations were not observed among preschool-aged children and preadolescents. Birth weight and gestational age were strongly associated with BP among 6-year-old children, particularly girls, but not among preschoolers or preadolescents.


Subject(s)
Birth Weight , Blood Pressure/physiology , Gestational Age , Anthropometry , Blood Pressure Determination , Child , Child, Preschool , Female , Humans , Linear Models , Male
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