ABSTRACT
Glomus tumours are uncommon lesions of the digit. They tend to be solitary. Only a small number of multifocal cases have been published, most of which are linked to an underlying genetic disorder. Here we report an unusual case of multifocal glomus tumours in the same hand in a patient suffering from neurofibromatosis type 1.
Subject(s)
Glomus Tumor/diagnosis , Nail Diseases/diagnosis , Neurofibromatosis 1/complications , Skin Neoplasms/diagnosis , Adult , Diagnosis, Differential , Diagnostic Imaging , Glomus Tumor/pathology , Glomus Tumor/surgery , Humans , Male , Nail Diseases/pathology , Nail Diseases/surgery , Skin Neoplasms/pathology , Skin Neoplasms/surgeryABSTRACT
Although there is no evidence that imported tuberculosis increases the incidence of the disease in host countries, the rise in migration worldwide raises concerns regarding the adequacy of surveillance and control of immigrant-associated tuberculosis in low incidence countries. Assessing the performance of screening of immigrants for tuberculosis is key to rationalizing control policies for the detection and management of immigrant-associated tuberculosis. We performed a systematic review and meta-analysis to determine the yield of active screening for tuberculosis among new immigrants at the point of entry. The yield for pulmonary tuberculosis was 3.5 cases per 1,000 screened (95% CI 2.9-4.1; I(2) = 94%); for refugees, asylum seekers and regular immigrants the estimates were 11.9 (95% CI 6.7-17.2; I(2) = 92%), 2.8 (95% CI 2.0-3.7; I(2) = 96%) and 2.7 (95% CI 2.0-3.4; I(2) = 81%), respectively. The yield estimates for immigrants from Europe, Africa and Asia were 2.4 (95% CI 1.3-3.4; I(2) = 51.5%), 6.5 (95% CI 3.2-10.0; I(2) = 62%) and 11.2 (95% CI 6.2-16.1; I(2) = 95%), respectively. These results provide useful data to inform the development of coherent policies and rational screening services for the detection of immigrant-associated tuberculosis.
