ABSTRACT
OBJECTIVE: To study the role of fine needle aspiration (FNA) in male infertility and in nonneoplastic lesions of the testis and scrotum. STUDY DESIGN: In a retrospective study over a 5-year period, 164 cases of FNA of testicular and scrotal nonneoplastic lesions were retrieved. Aspiration was performed with a 23-gauge needle on a 20-mL syringe. RESULTS: Of 164 cases, 27 (16%) remained inconclusive; they were mainly from epididymal lesions. The remaining 137 cases were categorized as inflammatory lesions, 52 (31.7%); noninflammatory lesions, 42 (25.6%); and infertility cases, 43 (26.2%). Among the inflammatory lesions, 33 cases had nonspecific inflammation, 13 had granulomatous epididymoorchitis, 3 cases were of spermatic granuloma, and 3 cases revealed microfilariae. Noninflammatory lesions included 25 cases of spermatocele, 8 of hematoma/torsion, 5 of hydrocele, 3 of benign epididymal cyst and 1 of calcinosis cutis. Among the patients investigated for infertility, 23 (53%) had normal spermatogenesis, 6 (14%) had Sertoli cells only, 5 (119%) had maturation arrest, 6 (14%) showed hypospermatogenesis, and 3 (7%) showed an atrophic pattern. CONCLUSION: FNA of the testis and scrotum is a simple, quick, minimally invasive and painless outpatient procedure. The sample obtained is more representative than biopsy as several separate punctures can be made, and there is no local scarring.
Subject(s)
Biopsy, Fine-Needle , Infertility, Male/diagnosis , Scrotum/pathology , Testicular Diseases/diagnosis , Testis/pathology , Biopsy, Fine-Needle/instrumentation , Cysts/diagnosis , Epididymitis/diagnosis , Granuloma/diagnosis , Humans , Male , Orchitis/diagnosis , Predictive Value of Tests , Reproducibility of Results , Retrospective Studies , Spermatocele/diagnosis , Spermatocytes/pathology , Testicular Hydrocele/diagnosis , Testis/cytologyABSTRACT
Hepatobiliary cystadenoma with mesenchymal stroma (HCMS) is a rare lesion characterized by multiloculated cyst lined by columnar epithelium ad mesenchymal stroma. It occurs exclusively in females and is intrahepatic in location with only 17% cases arising in extrahepatic biliary tree. Exact histogenesis is not known, but it is hypothesized the HCMS arises from ectopic embryonic tissue destined to form the adult gall bladder. HCMS has got a malignant potential and requires radical excision.
Subject(s)
Bile Duct Neoplasms/pathology , Cystadenoma/pathology , Liver Neoplasms/pathology , Bile Duct Neoplasms/diagnosis , Bile Ducts, Extrahepatic/pathology , Cystadenoma/diagnosis , Female , Humans , Liver Neoplasms/diagnosis , Middle AgedABSTRACT
BACKGROUND: Granulomatous prostatitis is an unusual benign inflammatory process of the prostate. Clinically, it mimics prostatic carcinoma, thus requiring pathological examination for diagnosis. MATERIALS AND METHODS: Histopathological records of 1353 prostate specimens received in the Department of Pathology, Government Medical College, Chandigarh, India, over a period of 8 years (1995-2002) were reviewed and 20 cases of granulomatous prostatitis were retrieved. RESULTS: Out of 20 cases of granulomatous prostatitis, we encountered 12 cases of non-specific granulomatous prostatitis, two cases of xanthogranulomatous prostatitis, two cases of tuberculous prostatitis, two cases of malakoplakia prostate and one case each of granulomatous prostatitis associated with adenocarcinoma prostate and post-surgical palisading granuloma. The diagnosis was made by histopathological examination of Trucut biopsy, transuretheral resection of prostate chips or retropubic prostatectomy specimen. In all the cases, granulomatous prostatitis was an incidental finding. CONCLUSIONS: Non-specific granulomatous prostatitis is the most common type of granulomatous prostatitis. Despite tuberculosis being very common in India, granulomatous prostatitis associated with tuberculosis is not common. Distinction between non-specific and infectious granulomatous prostatitis is important for therapeutic reasons.
Subject(s)
Granuloma/diagnosis , Prostatitis/diagnosis , Adenocarcinoma/diagnosis , Aged , Aged, 80 and over , Biopsy , Diagnosis, Differential , Humans , Male , Middle Aged , Photomicrography , Prostatic Neoplasms/diagnosis , Retrospective StudiesABSTRACT
An adenocarcinoma arising in a horseshoe kidney (HK) is rare. The case of a forty five-year-old male patient, presenting with a recurrent, painless hematuria, is reported. On investigation the patient was found to have a horseshoe kidney, with an adenocarcinoma in the left hemi-kidney, which was treated surgically, with a hemi-nephrectomy, of the involved part, being performed to excise the tumor. A brief review of the relevant literature is also presented.
Subject(s)
Carcinoma, Renal Cell/complications , Kidney Neoplasms/complications , Kidney/abnormalities , Carcinoma, Renal Cell/pathology , Carcinoma, Renal Cell/surgery , Humans , Kidney/diagnostic imaging , Kidney Neoplasms/pathology , Kidney Neoplasms/surgery , Lymph Node Excision , Male , Middle Aged , Nephrectomy/methods , RadiographyABSTRACT
Squamous cell carcinoma of the prostate is rare, accounting for 0.5-1% of all prostatic cancers. It is highly aggressive and responds poorly to any mode of therapy. We present a case of squamous cell carcinoma of the prostate that developed in a patient with prostatic adenocarcinoma following radiation therapy.
