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1.
Int J Lang Commun Disord ; 36 Suppl: 511-6, 2001.
Article in English | MEDLINE | ID: mdl-11340841

ABSTRACT

In 1997 Salford Community Healthcare Trust embarked on a research project (funded by NHS Executive North West Region) to investigate how viable the Hanen Parent Programme (HPP) (Manolson 1992) was in terms of its effectiveness and suitability for an inner-city UK population in comparison with clinic-based, direct intervention. An important component of that research project involved exploring the parents' perceptions of the therapy they had undertaken. In this paper are summarised the areas in which there were marked differences between parents' experiences and perceptions of therapy as a result of the type of intervention they received. Clinical implications are discussed.


Subject(s)
Attitude , Communication Disorders/therapy , Parents/psychology , Speech Therapy/standards , Child , Humans , Program Evaluation , Urban Population
2.
Science ; 287(5461): 2185-95, 2000 Mar 24.
Article in English | MEDLINE | ID: mdl-10731132

ABSTRACT

The fly Drosophila melanogaster is one of the most intensively studied organisms in biology and serves as a model system for the investigation of many developmental and cellular processes common to higher eukaryotes, including humans. We have determined the nucleotide sequence of nearly all of the approximately 120-megabase euchromatic portion of the Drosophila genome using a whole-genome shotgun sequencing strategy supported by extensive clone-based sequence and a high-quality bacterial artificial chromosome physical map. Efforts are under way to close the remaining gaps; however, the sequence is of sufficient accuracy and contiguity to be declared substantially complete and to support an initial analysis of genome structure and preliminary gene annotation and interpretation. The genome encodes approximately 13,600 genes, somewhat fewer than the smaller Caenorhabditis elegans genome, but with comparable functional diversity.


Subject(s)
Drosophila melanogaster/genetics , Genome , Sequence Analysis, DNA , Animals , Biological Transport/genetics , Chromatin/genetics , Cloning, Molecular , Computational Biology , Contig Mapping , Cytochrome P-450 Enzyme System/genetics , DNA Repair/genetics , DNA Replication/genetics , Drosophila melanogaster/metabolism , Euchromatin , Gene Library , Genes, Insect , Heterochromatin/genetics , Insect Proteins/chemistry , Insect Proteins/genetics , Insect Proteins/physiology , Nuclear Proteins/genetics , Protein Biosynthesis , Transcription, Genetic
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