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Diagn Microbiol Infect Dis ; 108(2): 116130, 2024 Feb.
Article in English | MEDLINE | ID: mdl-38006710

ABSTRACT

Pseudomonas aeruginosa clinical isolates demonstrating difficult-to-treat resistance (DTR) and multidrug-resistant (MDR) phenotypes were evaluated by broth microdilution. Susceptibility was lower for all antimicrobials versus DTR relative to MDR isolates. Ceftazidime-avibactam, ceftolozane-tazobactam, and imipenem-relebactam susceptibility was 35.9%, 64.5%, and 47.0% for DTR isolates and 60.5%, 80.6%, and 71.5% for MDR isolates.


Subject(s)
Anti-Infective Agents , Pseudomonas Infections , Humans , Anti-Bacterial Agents/pharmacology , Anti-Bacterial Agents/therapeutic use , Pseudomonas aeruginosa , Drug Resistance, Bacterial , Ceftazidime/pharmacology , Ceftazidime/therapeutic use , Cephalosporins/pharmacology , Cephalosporins/therapeutic use , Pseudomonas Infections/drug therapy , Anti-Infective Agents/pharmacology , Azabicyclo Compounds/pharmacology , Azabicyclo Compounds/therapeutic use , Drug Combinations , Microbial Sensitivity Tests , Drug Resistance, Multiple, Bacterial
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