ABSTRACT
We present a case diagnosed with hepatosplenic sarcoidosis with hypercalcemia. Elevated liver enzymes and hypercalcemia were detected in the patient who was admitted to the hospital with abdominal pain and dyspnea. Abdominal dynamic magnetic resonance imaging (MRI) showed diffuse, multiple, nodular hyperintense lesions on T2 weighted. Multinuclear giant cells and lymphocytic portal inflammation were seen in the patient's liver biopsy, whose angiotensin-converting enzyme level was high, and hepatosplenic sarcoidosis was diagnosed. Shortness of breath, abdominal pain, and calcium level improved with methylprednisolone treatment.
ABSTRACT
CASE PRESENTATION: A 24-year-old woman, a baby-sitter with no known comorbidities, presented to the outpatient department with complaints of modified Medical Research Council grade IV breathlessness for 3 months, chest pain, and dry cough for 2 weeks. There was no known disease history, including respiratory, flu-like illness, or connective tissue disorder. There was no use of chemotherapeutic, oral contraceptive drugs, exposure to toxic substances, or smoking. A review of systems was negative for fever, arthralgia, myalgia, Raynaud phenomenon, skin thickening, rash, or leg swelling. The patient had no family history suggestive of a genetic syndrome.
Subject(s)
Hemangioma, Capillary/diagnosis , Hypertension, Pulmonary/diagnosis , Lung Neoplasms/diagnosis , Protein Serine-Threonine Kinases/genetics , Pulmonary Veno-Occlusive Disease , Pyrimidines/administration & dosage , Sildenafil Citrate/administration & dosage , Sulfonamides/administration & dosage , Chest Pain/diagnosis , Chest Pain/etiology , Computed Tomography Angiography/methods , Cough/diagnosis , Cough/etiology , Diagnosis, Differential , Dyspnea/diagnosis , Dyspnea/etiology , Echocardiography/methods , Endothelin A Receptor Antagonists/administration & dosage , Female , Humans , Hypertension, Pulmonary/etiology , Hypertension, Pulmonary/physiopathology , Lung Transplantation , Mutation , Oxygen Inhalation Therapy/methods , Phosphodiesterase 5 Inhibitors/administration & dosage , Pulmonary Veno-Occlusive Disease/complications , Pulmonary Veno-Occlusive Disease/congenital , Pulmonary Veno-Occlusive Disease/diagnosis , Pulmonary Veno-Occlusive Disease/genetics , Respiratory Function Tests/methods , Young AdultABSTRACT
Horseshoe lung is a rare congenital anomaly characterized by the presence of unilateral pulmonary hypoplasia and a midline isthmus bridging the right and the left lung. Almost all cases of horseshoe lung are associated with the scimitar syndrome. The scimitar syndrome, sometimes called the congenital pulmonary venolobar syndrome, is a rare but well-described constellation of cardio-pulmonary anomalies. The characteristic abnormality is anomalous pulmonary venous return from a part of or the entire right lung to the inferior vena cava. We present a case of horseshoe lung associated with scimitar syndrome and pleural lipoma in an adult admitted for acute chest pain and chronic dyspnea.
Subject(s)
Lipoma/complications , Lung/abnormalities , Pleural Neoplasms/complications , Scimitar Syndrome/complications , Chest Pain/etiology , Diagnosis, Differential , Dyspnea/etiology , Female , Humans , Lipoma/diagnostic imaging , Lung/diagnostic imaging , Lung/pathology , Magnetic Resonance Imaging/methods , Middle Aged , Pleural Neoplasms/diagnostic imaging , Rare Diseases , Spirometry/methods , Tomography, X-Ray Computed/methodsABSTRACT
Fagerstom Test for Nicotine Dependence (FTND) has often been used as a measure of physical dependence on nicotine. In this study, we aimed to verify the usefulness of FTND and Heaviness of Smoking Index (HSI) in a sample of Turkish smokers and present relationship among interrelated items in our Turkish version of FTND by factor analysis. One hundred sixty nine smokers, 104 (61.5%) males, 65 (38.5%) females smoker were administered the Turkish translation of FTND. Fifty-two current smokers selected randomly from 169 were administered the questionnaire for test- retest reliability analysis. The Turkish version of FTND had moderate reliability (Cronbach alpha: 0.56). One FTND item (question 3: hate- most to give up) performed poorly on construct reliability tests. Factor 1 was loaded by questions 1 (first cigarette after awakening), 4 (number of cigarettes per day), 5 (smoking status during the first hours), 6 (smoking if ill), 2 (refrain from smoking in forbidden places) and factor 2 was separately loaded by question 3. Question 3 did not have significant correlation with the total score and the response to this question was significant between test and retest. The Turkish version of FTND may become a measuring tool in the assessment of smoking cessation programs. However, question 3 must be used attentively and preferably an explanation should be made to enable a clear understanding of the question to the Turkish smokers as they take the test.
