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Vopr Onkol ; 55(3): 319-26, 2009.
Article in Russian | MEDLINE | ID: mdl-19670732

ABSTRACT

The investigation involved 285 patients suffering from recurrences and distant metastases of uterine carcinoma cases of 24% of all (primary tumor). All recurrences generally occurred 12-20 months after the beginning of specialized therapy in 3.3-40%, with 78.3% detected within the first 24 months. Relapse was reported mostly in groups in which a single modality was used: surgery (32.4%) or radiotherapy (24.7%). Local recurrence rate for primary squamous cell tumor was 53.6%, adenocarcinoma - 6.3% and poorly-differentiated cell carcinoma - 4.9%. Complete regression of relapse following combined treatment was reported in 19% versus 14% and 4% after radiotherapy and chemotherapy, respectively. Moreover, more apparent responses were registered as a result of combinations of modalities (69%) as compared with 26% and 20% for radio- and chemotherapy, respectively.


Subject(s)
Carcinoma/secondary , Carcinoma/therapy , Neoplasm Recurrence, Local/therapy , Uterine Cervical Neoplasms/pathology , Uterine Cervical Neoplasms/therapy , Adenocarcinoma/secondary , Adenocarcinoma/therapy , Adult , Carcinoma/drug therapy , Carcinoma/radiotherapy , Carcinoma/surgery , Carcinoma, Squamous Cell/secondary , Carcinoma, Squamous Cell/therapy , Chemotherapy, Adjuvant , Female , Humans , Intestinal Neoplasms/secondary , Intestinal Neoplasms/therapy , Lymphatic Metastasis , Middle Aged , Neoplasm Invasiveness , Neoplasm Recurrence, Local/drug therapy , Neoplasm Recurrence, Local/radiotherapy , Neoplasm Recurrence, Local/surgery , Radiotherapy, Adjuvant , Retrospective Studies , Treatment Outcome , Urologic Neoplasms/secondary , Urologic Neoplasms/therapy , Uterine Cervical Neoplasms/drug therapy , Uterine Cervical Neoplasms/radiotherapy , Uterine Cervical Neoplasms/surgery
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