1.
Minerva Med
; 66(67): 3509-33, 1975 Oct 10.
Article
in Italian
| MEDLINE
| ID: mdl-1103007
ABSTRACT
The results of a set of experiments conducted on a new non-steroid antirheumatic preparation--pyrasanone (Carudol)--are presented and its indications in the general management of the disease are noted. The pharmacokinetics and therapeutic efficacy of the new drug are described. Statistical analysis showed it to be more effective than hexahydropyrazine, diphenylbutazone, indomethacin and oxyphenbutazone. A basic therapeutic approach is suggested in accordance with the pharmacodynamic aspects of the drug and the results observed in a clinical trial on 719 subjects. Pyrasanone has low toxicity and is well tolerated. Due caution in the administration of antirheumatic drugs should nevertheless be maintained during its use.
Subject(s)
Anti-Inflammatory Agents/therapeutic use , Phenylbutazone/analogs & derivatives , Phenylbutazone/therapeutic use , Rheumatic Diseases/drug therapy , Adult , Aged , Anti-Inflammatory Agents/administration & dosage , Anti-Inflammatory Agents/adverse effects , Clinical Trials as Topic , Drug Evaluation , Female , Gout/drug therapy , Humans , Indomethacin/therapeutic use , Male , Middle Aged , Oxyphenbutazone/therapeutic use , Phenylbutazone/administration & dosage , Phenylbutazone/adverse effects
2.
Reumatismo
; 27(1): 255-8, 1975.
Article
in Italian
| MEDLINE
| ID: mdl-1233641
3.
Reumatismo
; 24(3): 205-12, 1972.
Article
in Italian
| MEDLINE
| ID: mdl-4681330
4.
Minerva Med
; 59(3): 71-8, 1968 Jan 13.
Article
in Italian
| MEDLINE
| ID: mdl-5300479
Subject(s)
Aminopyrine/therapeutic use , Antipyrine/therapeutic use , Arthritis, Infectious/drug therapy , Arthritis, Rheumatoid/drug therapy , Hip Joint , Phenylbutazone/therapeutic use , Rheumatic Diseases/drug therapy , Shoulder Joint , Spondylitis, Ankylosing/drug therapy , Adolescent , Adult , Aged , Female , Humans , Male , Middle Aged
5.
Minerva Med
; 58(74): 3137-58, 1967 Sep 15.
Article
in Italian
| MEDLINE
| ID: mdl-6051031
6.
Arcisp S Anna Ferrara
; 19(4): 467-530, 1966.
Article
in Italian
| MEDLINE
| ID: mdl-5959874