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J Am Acad Dermatol ; 61(2): 355-8, 2009 Aug.
Article in English | MEDLINE | ID: mdl-19615547

ABSTRACT

Blastomycosis is an infection caused by the dimorphic fungus Blastomyces dermatitidis. Infection can disseminate to skin, where characteristic ulcerative and verrucous plaques, sometimes studded with pustules, are typically seen. Herein we report 3 patients, two children and one adult, with pustular blastomycosis. Their cutaneous lesions exhibited a pustular morphology at the onset and throughout the course of their illness, without evolution to more typical verrucous or ulcerative plaques. These patients all resided in Memphis, TN, the site of previous case reports of pustular blastomycosis.


Subject(s)
Blastomyces/isolation & purification , Blastomycosis/diagnosis , Blastomycosis/drug therapy , Acute Disease , Adolescent , Aged , Amphotericin B/therapeutic use , Biopsy, Needle , Blastomycosis/mortality , Blastomycosis/pathology , Female , Follow-Up Studies , Humans , Immunohistochemistry , Infusions, Intravenous , Itraconazole/therapeutic use , Male , Risk Assessment , Sampling Studies , Severity of Illness Index , Survival Rate
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