Subject(s)
Amputation, Surgical , Compartment Syndromes/etiology , Extravasation of Diagnostic and Therapeutic Materials/complications , Forearm/surgery , Norepinephrine/administration & dosage , Adult , Compartment Syndromes/surgery , Extravasation of Diagnostic and Therapeutic Materials/diagnosis , Humans , Infusions, Intravenous , MaleSubject(s)
Accidents/statistics & numerical data , Off-Road Motor Vehicles , Trauma Centers , Wounds and Injuries/epidemiology , Accidents/mortality , Adolescent , Adult , Aged , Aged, 80 and over , Child , Child, Preschool , Female , Head Protective Devices/statistics & numerical data , Humans , Incidence , Male , Middle Aged , Tennessee/epidemiology , Trauma Severity Indices , Young AdultSubject(s)
Anal Canal/surgery , Endoscopy/methods , Lacerations/surgery , Rectum/injuries , Adult , Athletic Injuries/complications , Feasibility Studies , Female , Follow-Up Studies , Humans , Lacerations/diagnostic imaging , Lacerations/etiology , Laparotomy , Male , Minimally Invasive Surgical Procedures/methods , Patient Safety , Proctoscopy/methods , Rectum/surgery , Tomography, X-Ray Computed/methods , Treatment Outcome , Wounds, Gunshot/complicationsSubject(s)
Carotid Artery, Common/diagnostic imaging , Carotid Artery, Common/surgery , Carotid Stenosis/diagnostic imaging , Carotid Stenosis/therapy , Endovascular Procedures/methods , Stents , Angiography/methods , Carotid Artery, Common/pathology , Carotid Sinus/diagnostic imaging , Carotid Sinus/pathology , Carotid Sinus/surgery , Follow-Up Studies , Humans , Intraoperative Care/methods , Male , Middle Aged , Minimally Invasive Surgical Procedures/methods , Preoperative Care/methods , Risk Assessment , Sampling Studies , Severity of Illness Index , Treatment Outcome , Vascular Patency/physiologySubject(s)
Embolism/etiology , Femoral Artery/injuries , Vascular Surgical Procedures/methods , Wounds, Gunshot/complications , Adult , Angiography , Embolism/diagnosis , Embolism/surgery , Femoral Artery/surgery , Humans , Male , Tomography, X-Ray Computed , Wounds, Gunshot/diagnosis , Wounds, Gunshot/surgerySubject(s)
Abdominal Injuries/complications , Digestive System Surgical Procedures/methods , Hemangioma, Cavernous/complications , Liver Neoplasms/complications , Liver/injuries , Abdominal Injuries/diagnosis , Abdominal Injuries/surgery , Adult , Diagnostic Errors , Hemangioma, Cavernous/diagnosis , Hemangioma, Cavernous/surgery , Humans , Laparotomy , Liver/diagnostic imaging , Liver/surgery , Liver Neoplasms/diagnosis , Liver Neoplasms/surgery , Male , Rupture/diagnosis , Rupture/etiology , Rupture/surgery , Tomography, X-Ray ComputedSubject(s)
Abnormalities, Multiple/surgery , Cryptorchidism/surgery , Disorders of Sex Development/diagnosis , Mullerian Ducts/abnormalities , Seminoma/surgery , Testicular Neoplasms/surgery , Abnormalities, Multiple/diagnosis , Disorders of Sex Development/surgery , Fallopian Tubes/abnormalities , Fallopian Tubes/surgery , Female , Humans , Karyotype , Male , Middle Aged , Mullerian Ducts/surgery , Ovary/abnormalities , Ovary/surgery , Seminoma/diagnosis , Sex Determination Analysis , Syndrome , Testicular Neoplasms/diagnosis , Uterus/abnormalities , Uterus/surgeryABSTRACT
BACKGROUND: Nonoperative management (NOM) of solid abdominal organ injury (SAOI) is increasing. Consequently, training programs are challenged to ensure essential operative trauma experience. We hypothesize that the increasing use and success of NOM for SAOI negatively impacts resident operative experience with these injuries and that curriculum-based simulation might be necessary to augment clinical experience. MATERIALS AND METHODS: A retrospective cohort analysis of 1198 consecutive adults admitted to a Level I trauma center over 12 y diagnosed with spleen and/or liver injury was performed. Resident case logs were reviewed to determine operative experience (Cohort A: 1996-2001 versus Cohort B: 2002-2007). RESULTS: Overall, 24% of patients underwent operation for SAOI. Fewer blunt than penetrating injuries required operation (20% versus 50%, P < 0.001). Of those managed operatively, 70% underwent a spleen procedure and 43% had a liver procedure. More patients in Cohort A received an operation compared with Cohort B (34% versus 16%, P < 0.001). Patient outcomes did not vary between cohorts. Over the study period, 55 residency graduates logged on average 27 ± 1 operative trauma cases, 3.4 ± 0.3 spleen procedures, and 2.4 ± 0.2 liver operations for trauma. Cohort A graduates recorded more operations for SAOI than Cohort B graduates (spleen 4.1 ± 0.4 versus 3.0 ± 0.2 cases, P = 0.020 and liver 3.2 ± 0.3 versus 1.8 ± 0.3 cases, P = 0.004). CONCLUSIONS: Successful NOM, especially for blunt mechanisms, diminishes traditional opportunities for residents to garner adequate operative experience with SAOI. Fewer operative occasions may necessitate an increased role for standardized, curriculum-based simulation training.
Subject(s)
Abdominal Injuries/therapy , General Surgery/education , Internship and Residency , Patient Simulation , Wounds, Nonpenetrating/therapy , Abdominal Injuries/epidemiology , Adult , Clinical Competence , Cohort Studies , Female , Humans , Male , Retrospective Studies , Surgical Procedures, Operative/statistics & numerical data , Wounds, Nonpenetrating/epidemiologySubject(s)
Brain Injuries/complications , Embolization, Therapeutic/methods , Liver Cirrhosis/complications , Splenomegaly/therapy , Thrombocytopenia/complications , Accidental Falls , Blood Coagulation Disorders/complications , Blood Coagulation Disorders/therapy , Brain Injuries/therapy , Humans , Liver Cirrhosis/therapy , Male , Middle Aged , Splenomegaly/etiology , Thrombocytopenia/therapyABSTRACT
BACKGROUND: On occasion, patients followed with positron emission tomographic (PET)/computed tomographic (CT) imaging for nonbreast malignancies will have incidental breast findings concerning for second primary breast cancers. The aim of this study was to determine the predictive value of PET/CT imaging to identify breast cancers in these patients. METHODS: Patients with primary nonbreast malignancies and findings concerning for second primary breast cancers were identified from a prospectively acquired nuclear medicine database from January 2005 to July 2008. Chart reviews were then performed. RESULTS: Nine hundred two women underwent PET/CT imaging to evaluate nonbreast malignancies. Nine women (1%) had concerning breast findings, and 5 (56%) had subsequent breast cancer diagnoses. The positive predictive value of PET/CT imaging in these patients was 63%. Evidence of compliance with current screening guidelines was present in only 22% of these patients. CONCLUSIONS: The data suggest that findings concerning for an additional primary breast cancer should be evaluated and that age-appropriate screening tools should not be abandoned.
Subject(s)
Breast Neoplasms/diagnosis , Neoplasms, Second Primary/diagnosis , Positron-Emission Tomography , Tomography, X-Ray Computed , Adult , Aged , Aged, 80 and over , Female , Humans , Incidental Findings , Mammography , Mass Screening , Middle Aged , Predictive Value of Tests , Young AdultABSTRACT
BACKGROUND: Despite a paucity of evidence-based guidelines, the use of PET/CT (positron emission tomography/computed tomography) in the management of cancer patients is increasing. As widespread clinical application increases, unexpected radiographic findings are occasionally identified. These incidental findings are often suspicious for a second primary malignancy. The purpose of this study was to determine the clinical impact of these incidental PET/CT findings. METHODS: A query of our prospectively acquired Nuclear Medicine database was performed to identify patients with a known malignancy being staged or serially imaged with PET/CT. Patients with incidental findings suggestive of a second primary malignancy were selected. Statistical analysis was performed to determine the ability of PET/CT to identify a second primary malignancy. All PET/CT were interpreted by board certified nuclear radiologists. RESULTS: Of 3,814 PET/CT scans performed on 2,219 cancer patients at our institution from January 1, 2005, to December 29, 2008, 272 patients (12% of all patients) had findings concerning for a second primary malignancy. An invasive work-up was performed on 49% (133/272) of these patients, while 15% (40/272) had no further evaluation due to an advanced primary malignancy. The remaining 36% (99/272) had no further evaluation secondary to a low clinical suspicion determined by the treating team, a clinical plan of observation, or patients lost to follow-up. Of the 133 patients evaluated further, clinicians identified a second primary malignancy in 41 patients (31%), benign disease in 62 patients (47%), and metastatic disease from their known malignancy in 30 patients (23%). The most common sites for a proven second primary malignancy were: lung (N = 10), breast (N = 7), and colon (N = 5). Investigation of these lesions was performed using several techniques, including 24 endoscopies (6 malignant). A surgical procedure was performed in 74 patients (29 malignant), and a percutaneous biopsy was performed on 34 patients (12 malignant). The overall positive predictive value for PET/CT to detect a second primary malignancy was 31% in this subgroup. At a median follow-up of 22 months, 9 of 41 patients with a second primary were dead of a malignancy, 20 were alive with disease, and 12 had no evidence of disease. CONCLUSION: Incidental PET/CT findings consistent with a second primary are occasionally encountered in cancer patients. In our data, approximately half of these findings were benign, a third were consistent with a second primary malignancy or a metastatic focus, and the remainder were never evaluated due to physician and patient decision. Advanced primary tumors are unlikely to be impacted by a second primary tumor suggesting that this subset of patients will not benefit from further investigation. Our data suggests that, despite the high rate of false positivity, incidental PET/CT findings should be investigated when the results will impact treatment algorithms. The timing and route of investigation should be dictated by clinical judgment and the status of the primary tumor. Further investigation will need to be performed to determine the long-term clinical impact of incidentally identified second primary malignancies.