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1.
Rev Sci Instrum ; 83(2): 02B304, 2012 Feb.
Article in English | MEDLINE | ID: mdl-22380283

ABSTRACT

A 2.45 GHz microwave ion source coupled with a magnesium charge exchange canal (C × C) has been successfully adapted to a large acceptance radiocarbon accelerator mass spectrometry system at the National Ocean Sciences Accelerator Mass Spectrometry (AMS) Facility, Woods Hole Oceanographic Institution. CO(2) samples from various preparation sources are injected into the source through a glass capillary at 370 µl∕min. Routine system parameters are about 120-140 µA of negative (12)C current after the C × C, leading to about 400 (14)C counts per second for a modern sample and implying a system efficiency of 0.2%. While these parameters already allow us to perform high-quality AMS analyses on large samples, we are working on ways to improve the output of the ion source regarding emittance and efficiency. Modeling calculations suggest modifications in the extraction triode geometry, shape, and size of the plasma chamber could improve emittance and, hence, ion transport efficiency. Results of experimental tests of these modifications are presented.

2.
Arch Fam Med ; 3(6): 545-8, 1994 Jun.
Article in English | MEDLINE | ID: mdl-8081534

ABSTRACT

Volatile nitrites are illegally marketed compounds that have been inhaled by persons who believe that they cause sexual arousal. These substances have been associated with significant hemolysis of red blood cells in patients with decreased or normal glucose-6-phosphate dehydrogenase levels because such nitrites act as cell-membrane oxidants. We report herein a case of hemolysis in a patient with an underlying glucose-6-phosphate dehydrogenase deficiency associated with the use of volatile nitrites, and we also review the literature of volatile nitrite-induced hemolytic anemia.


Subject(s)
Anemia, Hemolytic/chemically induced , Nitrites/adverse effects , Substance-Related Disorders/complications , Adolescent , Anemia, Hemolytic/diagnosis , Anemia, Hemolytic/physiopathology , Erythrocytes/enzymology , Glucosephosphate Dehydrogenase/drug effects , Humans , Male
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