ABSTRACT
The synthesis of the ethylenediamine-connected cyclodextrin dimer is reported, together with the syntheses of several reference cyclodextrinylamines. Each compound displayed enhanced transacylation or transphosphorylation of activated substrates, with the primary amine-bearing monocyclodextrin compound showing the greatest activity. No special rate advantage was observed for this cyclodextrin dimer, although such effects do exist in other cycloextrin dimers reported previously.
Subject(s)
Cyclodextrins/chemical synthesis , beta-Cyclodextrins , Acylation , Cyclodextrins/chemistry , Ethylenediamines/chemical synthesis , Ethylenediamines/chemistry , Kinetics , Molecular Structure , PhosphorylationABSTRACT
The structure-quenching relationship in 9-aminoalkylanthracenes is examined by the synthesis and fluorescence evaluation of five derivatives; it is observed that benzylic 2° and 3° amines lead to ≥95% quenching of anthracene fluorescence in water, while other amines afford substantially lower quenching efficiencies.
