[Radiotherapy of esophageal cancer using local hyperthermia and metronidazole (polyradiomodification)]. / Luchevaia terapiia raka pishchevoda s ispol'zovaniem lokal'noi gipertermii i metronidazola (poliradiomodifikatsiia).

The results of a dynamic course of radiotherapy alone and in combination with local hyperthermia and metronidazole were studied in 107 patients with esophageal cancer. With relation to the methods applied the patients were divided into 4 groups: the 1st group (40 patients) was given radiotherapy, the 2nd group (24 patients) radiotherapy and metronidazole, the 3rd group (20 patients) radiotherapy and local hyperthermia, and the 4th group (18 patients) radiotherapy, metronidazole and local hyperthermia. The general direct therapeutic efficacy and 1-year survival for the 1st group were 75 and 76.7% respectively, for the 2nd group 79.3 and 86.9%, for the 3rd group 100 and 95%, and for the 4th group 100 and 94.4%. Thus, a high efficacy of polyradiomodification in esophageal cancer was established.

[Immediate results of polychemotherapy in esophageal cancer patients]. / Neposredstvennye rezul'taty polikhimioterapii u bol'nykh rakom pishchevoda.

Short-term results of intensive 5-day polychemotherapy given to patients with esophageal cancer are presented. The drug therapy was mainly indicated for dramatic disorders of esophageal patency for liquid food (18 patients) or for its complete lack (5 patients). As a result of the treatment esophageal patency improved in 17 of the 23 patients (73.3%). This made it possible to give up palliative surgery and to carry out x-ray treatment.

[Comparative clinical and dosimetric analysis of radiotherapy variants in cervical cancer]. / Sravnitel'nyi kliniko-dozemetricheskii analiz variantov luchevogo lecheniia bol'nykh rakom sheiki matki

The authors estimated comparatively in 200 clinical patients the results of external irradiation of cervical cancer using two variants of gammatherapy: standard, 4--5 fields irradiation and improved one from 2 central contralateral fields in combination with a splitting lead block. The use of the improved variant of distance gammatherapy, compared with the standard one enabled the authors: 1) to reduce irradiation load on the minor pelvis organs and pelvic bones as much as 2--25 times; 2) to gain more even distribution of radiation on the lesion focus; 3) to reduce irradiation load on the organism, as a whole, in adequate focal dosage at point A and B, thus lessening radiation complications; 4) to simplify considerably centring and to shorten the exposure procedure that contributes to better efficiency of a gammatherapy machine; 5) to increase the effectiveness of combined radiotherapy for cancer of the uterine neck.