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An unusual rearrangement product formed during production of mometasone furoate (Sch 32088).
Puar, M S; Thompson, P A; Ruggeri, M; Beiner, D; McPhail, A T.
Steroids ; 60(9): 612-4, 1995 Sep.
Article in English | MEDLINE | ID: mdl-8545849

ABSTRACT

The structure of an unusual rearrangement product obtained during the production of mometasone furoate (Sch 32088) was assigned on the basis of NMR and X-ray crystallography data.


Subject(s)
Pregnadienediols/chemical synthesis , Pregnatrienes/chemical synthesis , Administration, Topical , Anti-Inflammatory Agents/chemical synthesis , Crystallography, X-Ray , Glucocorticoids , Magnetic Resonance Spectroscopy , Molecular Structure , Mometasone Furoate , Pregnadienediols/chemistry , Pregnatrienes/chemistry
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