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Eksp Klin Farmakol ; 76(7): 24-6, 2013.
Article in Russian | MEDLINE | ID: mdl-24006612

ABSTRACT

It has been shown that specific binding of dydrogesterone with progesterone receptors in blood mononuclear cells of the patients included in the programs of in vitro fertilization, varies from 0 to 298%, thus at 38% of women dydrogesterone concedes to a progesterone in the competition for receptors of a progesterone, and 62%--exceed. The revealed variations of specific binding dydrogesterone with receptors of a progesterone are a reserve of increase of efficiency of auxiliary reproductive technology at the expense of individual selection of hormonal agents.


Subject(s)
Dydrogesterone/metabolism , Fertilization in Vitro , Leukocytes, Mononuclear/metabolism , Receptors, Progesterone/metabolism , Adult , Female , Humans , Leukocytes, Mononuclear/cytology , Protein Binding
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