ABSTRACT
Peculiarities of topography and stereometry of the heart hemomicrocirculatory bed were studied by method of scanning electron microscopy of corrosive preparations. Different links of the heart hemomicrocirculatory bed were found to have expressed morphological signs, revealed distinctively by the methods named. This allows to differentiate them and to carry out an analysis of their functional peculiarities.
Subject(s)
Lymphatic System/ultrastructure , Myocardium/ultrastructure , Adult , Animals , Corrosion Casting , Endothelium, Vascular/ultrastructure , Humans , Microcirculation/ultrastructure , Microscopy, Electron, Scanning , RatsABSTRACT
The method of scanning electron microscopy of cast preparations was used to study the volumetric interrelations of hemo- and lymph microcirculation bed links as well as specific features of the relief of the wall of the heart vessels in question. The lymphangions were confirmed to be rightfully considered as a morphological unit of the lymph microcirculation bed. The valve-shaped impressions and folds of the relief of a cast of lymph capillaries and postcapillaries were found which shows the ability of the lymph postcapillaries to maintain a one-direction flow of lymph and to change the lumen width for different amounts of the flowing lymph.
Subject(s)
Myocardium/ultrastructure , Animals , Corrosion Casting , Humans , Lymphatic System/ultrastructure , Male , Microcirculation/ultrastructure , Microscopy, Electron, Scanning , Rats , Rats, WistarABSTRACT
By means of intraorganic impregnation of microvessels, it is possible to reveal simultaneously the hemo- and lymphomicrocirculatory beds in the rat and dog hearts and to analyse morphological peculiarities in all parts of the myocardial microcirculatory bed--arterioles, precapillaries, capillaries, postcapillaries, prevenules, venules. It has been demonstrated that the cardiac hemomicrocirculatory bed possesses certain structural-functional units, common for the whole microvascular bed, precapillary sphincters, metarterioles, as well as capillary "sphincters" and arteriolo-venular anastomoses. Lymphatic microvessels of the myocardium are represented by precapillaries and capillaries, the latter varying in their form. The main structural units of the myocardial lymphatic network are reservoir-like microvessels having an essential capicity; at alteration of systole and diastole they perform the role of a specific pump for smaller lymphatic capillaries. Owing to the morphological data obtained, it is possible to interprete anew the mechanisms of the myocardial lymphatic outflow.
Subject(s)
Coronary Vessels/anatomy & histology , Heart/anatomy & histology , Lymphatic System/anatomy & histology , Animals , Arteriovenous Anastomosis/anatomy & histology , Dogs , Female , Male , Microcirculation/anatomy & histology , Muscle, Smooth, Vascular , Rats , Rats, Inbred StrainsABSTRACT
The surface structures of peritoneal macrophages of mice were investigated with a scanning electron microscope RZEM-500. The study revealed 3 types of the macrophages. Macrophages of type 1 predominated in intact mice. These macrophages are cells rounded or oval in shape with a great number of compact finger-like excresences differing in size and form. In the animals treated with prodigiozan in a single dose of 150 mg/kg, the majority of the macrophages were larger in size and had a changed surface: spread, with many branches, "train", undulated membranes. Formation of a great number of macrophagal and macrophagal-lymphocytic clusters evident of the increased cell cooperation under the effect of prodigiozan was shown. The morphological changes in the surface structures of the macrophages under the effect of prodigiozan in vivo indicate an increase in their functional activity.