ABSTRACT
94 patients with primary diagnosis "adrenal incidentaloma" were operated. Ultrasound investigation, MR-tomography, computed tomography, hormonal tests were made in examination of these patients. The results were compared with morphology and histochemistry of the removed adrenals. True hormonally inactive tumors were detected in 11 cases only. The conclusion is made that the term "adrenal incidentaloma" is a collective term which does not reflect the essence of the processes in the adrenals. Verification of morphofunctional features of adrenal tumors is possible only after clinical and morphobiochemical examinations.
Subject(s)
Adrenal Gland Neoplasms/pathology , Hormones/metabolism , Adolescent , Adrenal Gland Neoplasms/metabolism , Adult , Aged , Female , Humans , Male , Middle AgedSubject(s)
Adrenal Cortex Diseases/genetics , Cushing Syndrome/genetics , Adrenal Cortex Diseases/congenital , Adult , Female , Humans , Male , Middle AgedABSTRACT
Method of dermal adrenal hyperfunctional suppression under CT-control in Itsenko-Cushing disease has been offered. Studies in the laboratory and in the clinic have revealed that this method is a method of choice in treatment of mild and middle forms of Itsenko-Cushing disease.
Subject(s)
Adrenocortical Hyperfunction/therapy , Cushing Syndrome/therapy , Tomography, X-Ray Computed , Adrenal Glands/diagnostic imaging , Adrenocortical Hyperfunction/diagnostic imaging , Animals , Combined Modality Therapy , Cushing Syndrome/diagnostic imaging , Diatrizoate Meglumine/administration & dosage , Dogs , Ethanol/administration & dosage , Humans , Male , Pituitary Irradiation , Radiography, Interventional , Remission Induction , Sclerotherapy/methodsABSTRACT
Altogether 15 untreated patients aged 16 to 55 with diffuse toxic goiter had morphologically confirmed diagnosis of the presence of antibodies to Coxsackie virus (group B); titers of group A (1:128 and more) were revealed in 3 of them. It indicated recent (not more than 2 yrs.) Coxsackie virus infection. Such titers were absent in the control group (18 healthy persons). Difference in the study and control groups was statistically significant (p less than 0.05). The role of Coxsackie virus in the breakdown of natural tolerance to autologous thyroid tissue was discussed.
