1.
J Mycol Med
; 28(1): 211-214, 2018 Mar.
Article
in English
| MEDLINE
| ID: mdl-29519625
ABSTRACT
Histoplasmosis is a fungal infection caused by a dimorphic fungus, Histoplasma capsulatum. We report a first case of disseminated histoplasmosis in a 34-year-old woman, infected with human immunodeficiency virus (HIV), originating from Ivory Coast and living in Tunisia for 4 years. She was complaining from fever, chronic diarrhoea and pancytopenia. The Histoplasma capsulatum var. capsulatum was identified by direct microscopic examination of the bone marrow. She was treated by Amphotericin B, relayed by itraconazole. Even though a regression of symptoms and normalization of blood cell count (BCC), the patient died in a respiratory distress related to CMV hypoxemic pneumonia.
Subject(s)
Bone Marrow/microbiology , HIV Infections/microbiology , Histoplasma/isolation & purification , Histoplasmosis/blood , Histoplasmosis/diagnosis , AIDS-Related Opportunistic Infections/complications , AIDS-Related Opportunistic Infections/epidemiology , AIDS-Related Opportunistic Infections/microbiology , AIDS-Related Opportunistic Infections/virology , Adult , Amphotericin B/therapeutic use , Antifungal Agents/therapeutic use , Communicable Diseases, Imported/epidemiology , Communicable Diseases, Imported/microbiology , Cote d'Ivoire/epidemiology , Fatal Outcome , Female , HIV Infections/complications , HIV Infections/epidemiology , Histoplasma/ultrastructure , Histoplasmosis/epidemiology , Histoplasmosis/microbiology , Humans , Itraconazole/therapeutic use , Microscopy , Respiratory Distress Syndrome/epidemiology , Respiratory Distress Syndrome/microbiology , Tunisia/epidemiology
2.
Tunis Med
; 73(1): 53-6, 1995 Jan.
Article
in French
| MEDLINE
| ID: mdl-9506123