ABSTRACT
The authors studied the properties of 115 strains of E. coli of serological group 03 isolated from 49 children and adults with acute intestinal disturbances. The majority of the children (82.9%) were aged under one year. Results of the study of the antigenic structure and biochemical properties permitted to differentiate the strains isolated into 3 serological types, with the prevalence of strains of type O3 : K2 (L) : H2 (78.3%), and 8 biochemical variants. The majority of the strains possessed hemolytic properties. Strains of serological group O3 were isolated repeatedly from the patients during the sickness, whereas none were revealed in examination of 132 healthy children and adults. The data obtained permitted to consider these microbes to be possible causative agents of intestinal coliinfection, and to refer them to the enteropathogenic category.
Subject(s)
Escherichia coli Infections/microbiology , Escherichia coli/physiology , Intestinal Diseases/microbiology , Acute Disease , Adult , Child, Preschool , Escherichia coli/classification , Fermentation , Hemolysis , Humans , Infant , SerotypingABSTRACT
A study of 88 E. coli strains belonging to serological group 06: K13 (L) isolated from 50 children and 5 adults suffering from acute intestinal disturbances permitted to refer them to the serological types 06: K13 (L):H1 (82 strains) and 06: K13 (L): H--(6 strains), and to 5 biochemical types. Repeated isolation of E. coli belonging to serlogical group 06: K13 (L) in patients with acute intestinal diseases, and their absence in healthy children and adults indicated these microbes to be a possible etiological factor of the disease and to refer to the group group of enteropathogenic ones. Wide introduction of agglutinating sera 06: K13(L) into the work of practical laboratories is of expedience in connection with this.
Subject(s)
Escherichia coli/immunology , Intestinal Diseases/microbiology , Acute Disease , Adult , Antigens, Bacterial/analysis , Child, Preschool , Colicins/pharmacology , Escherichia coli/enzymology , Escherichia coli/isolation & purification , Humans , Infant , SerotypingABSTRACT
Results of studying possibility of treatment of 589 patients suffering from Sonne dysentery at home showed that their significance in the spread of infection was not greater than that of those treated at the hospital. Significance of the patients in the spread of infection in a family was determined by their age, severity of the disease, number and duration of excretion of the causative agent. It was concluded that patients with forme frustes or subclinical form of Sonne dysentery and also those revealed during the late periods of the disease could by treated at home.
Subject(s)
Dysentery, Bacillary/therapy , Shigella sonnei , Adolescent , Adult , Age Factors , Child , Child, Preschool , Dysentery, Bacillary/transmission , Hospitalization , HumansABSTRACT
Results of studying the enzymatic (by maltose, rhamnose and xylose) properties of 9277 freshly-located Sh. sonnei strains isolated in Kharkov in 1965-1972 showed that they were referred to 14 enzymatic types (a, b, c, d, e, f, g, k, l, m, n, o, p, q). The strains under study were additionally--within the range of each of the enzymatic type-divided into 8 conditioned coli phi,cinogen types (I-VIII) by their sensitivity to colicines of the indicator E. coli, K12 and B cultures. Subdivision of the strains with the use of the two mentioned tests permitted to establish the prevalence among the Sh. sonnei strains isolated during the individual years of definite conditioned enzymatic-colicinogenic types. During the period observed group diseases were caused by Sh. sonnei of only some of the enzymatic-colicinogenic types-aII, aVI, dI, dII, dVI, etc. Three enzymatic types of Sh. sonnei-a, d and k-dominated in Kharkov beginning from 1969.
