1.
Biol Neonate
; 37(3-4): 197-203, 1980.
Article
in English
| MEDLINE
| ID: mdl-7362856
ABSTRACT
The capacity of mitochondria isolated from livers of 5-day-old piglets to convert pyruvate to phosphoenolpyruvate, malate and citrate has been investigated. These mitochondria have a large capacity to flux pyruvate through the pyruvate carboxylase reaction causing an accumulation of malate, citrate and phosphoenolpyruvate. As much as 70% of the pyruvate utilized during state 3 respiration can flux through the pyruvate carboxylase reaction. The data indicate that phosphoenolpyruvate from mitochondria can contribute a significant fraction of the carbon skeletons of pyruvate converted to glucose by piglet liver (estimated to be 30%).
Subject(s)
Animals, Newborn/metabolism , Mitochondria, Liver/metabolism , Phosphoenolpyruvate/metabolism , Animals , Citrates/metabolism , Gluconeogenesis , Malates/metabolism , Oxygen Consumption , Pyruvates/metabolism , Swine
2.
J Anim Sci
; 49(1): 250-7, 1979 Jul.
Article
in English
| MEDLINE
| ID: mdl-500510