ABSTRACT
HIV infection is one of the most acute problems of our time, characterized by slow development, prolonged course, and numerous clinical manifestations. Currently, there is a large number of drugs acting on different processes of human immunodeficiency virus replication, which constitute the group of highly active antiretroviral therapy (HAART). This article shows a theoretical review of modern HAART and analyzes the prescribed treatment regimens for patients with HIV infection. The study revealed two most common combinations: nucleoside reverse transcriptase inhibitors + protease inhibitors; nucleoside + non-nucleoside reverse transcriptase inhibitors.
Subject(s)
Antiretroviral Therapy, Highly Active , HIV Infections , Humans , HIV Infections/drug therapy , HIV Infections/virology , Anti-HIV Agents/therapeutic use , Reverse Transcriptase Inhibitors/therapeutic use , HIV Protease Inhibitors/therapeutic useABSTRACT
Echocardiography was conducted in patients who had suffered from myocardial infarction (47 were examined in the subacute period of myocardial infarction and 23 in more remote periods) with signs of mitral insufficiency and 31 patients with no signs of mitral insufficiency (they were examined in the subacute period of myocardial infarction). It was found that after myocardial infarction the contractility of the heart muscle is diminished to a greater extent in patients with signs of mitral insufficiency than in the others. In patients with mitral insufficiency symptoms of circulatory insufficiency were revealed more frequently. The mechanisms of the development of mitral insufficiency in patients with myocardial infarction are discussed.
