Your browser doesn't support javascript.
loading
Show: 20 | 50 | 100
Results 1 - 20 de 52
Filter
1.
JACC Case Rep ; 3(2): 212-216, 2021 Feb.
Article in English | MEDLINE | ID: mdl-34317504

ABSTRACT

Björk conduit failure is a common reason for reintervention after a Björk modification of the Fontan procedure. We describe a first performed in human percutaneous procedure for the treatment of a failing Björk circuit in an adult with congenital heart disease and complex anatomic features. (Level of Difficulty: Advanced.).

2.
Isr Med Assoc J ; 18(2): 104-7, 2016 Feb.
Article in English | MEDLINE | ID: mdl-26979003

ABSTRACT

BACKGROUND: Various vena cava filters (VCF) are designed with the ability to be retrieved percutaneously. Yet, despite this option most of them remain in the inferior vena cava (IVC). OBJECTIVES: To report our experience in the placement and retrieval of three different types of VCFs, and to compare the indications for their insertion and retrieval as reported in the literature. METHODS: During a 5 year period three types of retrievable VCF (ALN, OptEase, and Celect) were inserted in 306 patients at the Rabin Medical Center (Beilinson and Hasharon hospitals). Indications, retrieval rates, median time to retrieval, success and complication rates were viewed and assessed in the three groups of filter types and were compared with the data of similar studies in the literature. RESULTS: Of the 306 VCFs inserted, 31 (10.1%) were retrieved with equal distribution in the three groups. In most patients the reason for filter insertion was venous thromboembolic events (VTE) and contraindications to anticoagulant therapy. Mean age was 68.38 ± 17.5 years (range 18-99) and was noted to be significantly higher compared to similar studies (53-56 years) (P < 0.0001). Multi-trauma patients were significantly older (71.11 ± 14.99 years) than post-pulmonary embolism patients (48.03 ± 20.98 years, P < 0.0001) and patients with preventive indication (26.00 ± 11.31, P < 0.0001). The mean indwelling time was 100.6 ± 103.399 days. Our results are comparable with the results of other studies, and there was no difference in percentage of retrieval or complications between patients in each of the three groups. CONCLUSIONS: In 1 of 10 patients filters should be removed after an average of 3.5 months. All three IVC filter types used are safe to insert and retrieve.


Subject(s)
Vena Cava Filters , Vena Cava, Inferior/surgery , Venous Thromboembolism/prevention & control , Adolescent , Adult , Age Factors , Aged , Aged, 80 and over , Device Removal , Follow-Up Studies , Humans , Middle Aged , Pulmonary Embolism/prevention & control , Retrospective Studies , Time Factors , Vena Cava Filters/adverse effects , Young Adult
3.
Asian Cardiovasc Thorac Ann ; 23(1): 55-60, 2015 Jan.
Article in English | MEDLINE | ID: mdl-25053662

ABSTRACT

AIM: Bronchial artery angiography with embolization has become a mainstay in the treatment of massive hemoptysis. Whereas the immediate success rate is high, the reported long-term success rate varies widely among different groups. We aimed to explore the long-term outcome and clinical predictors associated with recurrent bleeding following bronchial artery embolization. METHODS: We reviewed the clinical characteristics, underlying etiologies, procedure details, and outcome of bronchial artery embolization performed for massive hemoptysis between 1999 and 2012. RESULTS: All 52 consecutive patients treated by bronchial artery embolization during the study period were included. The major etiologies of massive hemoptysis were bronchiectasis (mostly post-infectious) in 53.8%, and primary and metastatic lung cancer in 30.8%. The immediate success rate was high (48/52; 92%). Of 45 patients who survived more than 24 hours following bronchial artery embolization, recurrent bleeding did not occur in 19 (42.2%) during a median follow-up period of 60 months (range 6-130 months). Bleeding recurred in 26 (57.7%); within 30 days in 15 (33.3%) and after 1 month in the other 11 (24.4%). The average time to onset of early and late repeat bleeding was 2 and 506 days, respectively. Idiopathic bronchiectasis and lung cancer were associated with a high likelihood of late bleeding recurrence. CONCLUSIONS: Bronchial artery embolization is an effective immediate treatment for massive hemoptysis. Because the bleeding recurrence rate is high in patients with lung cancer or idiopathic bronchiectasis, surgery should be considered in these patients following initial stabilization by bronchial artery embolization. For other underlying etiologies, the long-term outcome is excellent.


Subject(s)
Bronchial Arteries , Embolization, Therapeutic/methods , Hemoptysis/surgery , Adult , Aged , Aged, 80 and over , Bronchial Arteries/diagnostic imaging , Bronchiectasis/complications , Embolization, Therapeutic/adverse effects , Embolization, Therapeutic/mortality , Female , Hemoptysis/diagnosis , Hemoptysis/etiology , Hemoptysis/mortality , Humans , Israel , Kaplan-Meier Estimate , Lung Neoplasms/complications , Male , Middle Aged , Multidetector Computed Tomography , Recurrence , Retrospective Studies , Risk Factors , Severity of Illness Index , Time Factors , Treatment Outcome
4.
J Vasc Interv Radiol ; 25(5): 702-6, 2014 May.
Article in English | MEDLINE | ID: mdl-24582172

ABSTRACT

PURPOSE: To describe the transvenous application of intracardiac echocardiography (ICE) for guidance during endovascular aortic repair (EVAR). MATERIALS AND METHODS: Eight patients with an infrarenal abdominal aortic aneurysm (AAA) and chronic renal failure were determined suitable for EVAR. The procedure was performed by deploying the transcaval and transiliac vein guidance of an ICE catheter to reduce the dosage of iodinated contrast medium. Multiple guidance parameters were assessed. The present study describes the EVAR procedure and postprocedure transabdominal ultrasound (US) follow-up results at 3-4 months. RESULTS: The eight procedures were completed by using transvenous ICE guidance. No contrast medium was used in five patients, and 3-20 mL of isoosmolar contrast medium was administered in the other three. No endoleaks were detected by ICE immediately after stent deployment. One patient who had a single functioning kidney developed renal failure that was attributed to manipulation-related cholesterol embolization. That patient became dependent on dialysis and died 3.5 months after the procedure. No endoleaks were detected at 3-4-month US follow-up in the other seven patients. CONCLUSIONS: Transvenous ICE guidance is a promising method to reduce the dosage of iodinated contrast medium in patients with renal dysfunction undergoing EVAR. A prospective trial comparing this modality versus digital subtraction angiography guidance with iodinated contrast medium in terms of safety, accuracy, and long-term efficacy is recommended.


Subject(s)
Aortic Aneurysm, Abdominal/surgery , Catheterization, Central Venous/methods , Endovascular Procedures/methods , Kidney Failure, Chronic/diagnostic imaging , Kidney Failure, Chronic/surgery , Ultrasonography, Interventional/methods , Aged , Aged, 80 and over , Female , Humans , Male , Treatment Outcome
5.
Cardiovasc Intervent Radiol ; 37(3): 686-90, 2014 Jun.
Article in English | MEDLINE | ID: mdl-24510277

ABSTRACT

OBJECTIVE: After lung transplantation, pulmonary artery stenosis (PAS) may occur at the anastomotic site, resulting in poor graft function and hypoxemia. Surgical repair has been the standard-of-care, although percutaneous angioplasty with stent insertion has been performed in patients unsuitable for surgery. We summarize our experience of pulmonary artery stent-graft placement in transplant recipients who were also fit for surgical repair. MATERIALS AND METHODS: Retrospective review of five cases of single-lung transplant recipients (4 male, 1 female, median age 61 years) who underwent percutaneous angioplasty and insertion of stent-graft for severe PAS. Balloon-expandable stent-grafts were used that were tailored to the donor and recipient vessel diameters. RESULTS: Stenosis was diagnosed with computed tomography angiography at a median of 44 days (range 22-84) after transplantation. All stent placements were technically successful. There was only one periprocedural complication, a haemothorax that was drained. In four patients, the angioplasty improved the lung function; relative graft perfusion (as assessed by quantitative lung scintigraphy) improved by 26 % (IQR 13-37); and SpO2 improved by 8 % (IQR 4-9). CONCLUSION: Percutaneous angioplasty using stent-graft is a minimally invasive, safe, and efficacious procedure for treatment of posttransplantation PAS and should be considered as an alternative to surgery even when the patient is considered fit for surgical repair.


Subject(s)
Angioplasty, Balloon , Postoperative Complications/therapy , Pulmonary Artery/pathology , Stents , Aged , Constriction, Pathologic , Female , Humans , Lung Transplantation , Male , Middle Aged , Postoperative Complications/diagnostic imaging , Retrospective Studies , Tomography, X-Ray Computed , Treatment Outcome
6.
Laryngoscope ; 123(5): 1220-6, 2013 May.
Article in English | MEDLINE | ID: mdl-23494563

ABSTRACT

OBJECTIVES/HYPOTHESIS: To present our 8-year experience with transarterial embolization for head and neck bleeding, with an emphasis on the need for repeated procedures in patients treated for head and neck cancer. STUDY DESIGN: Retrospective case series. METHODS: Tertiary university-affiliated medical center. The cohort included 49 patients who underwent transarterial embolization for acute head and neck bleeding in 2004 to 2012. Outcome measures included procedural success, recurrence, complications, and outcome. RESULTS: Mean patient age was 60.3 years. Indications for transarterial embolization were bleeding from a tumor (42%), nasal bleeding (36%), bleeding related to neck trauma (8%), tracheal stomal bleeding (8%), and other (4%). Twelve of 21 patients with tumors had been treated by chemoradiation. At least one repeated procedure was required in 11 patients, of whom nine had a history of chemoradiation and surgery for cancer; four of them required a stent for exclusion of pseudoaneurysm, and in six the recurrence presented late after the initial procedure (1 month to 5 years). Major complications included cerebrovascular accident in one patient and death due to major bleeding in two cases. Twenty-one patients died during follow-up, including nine patients with cancer. Eleven deaths occurred up to 4 years after embolization. CONCLUSIONS: Transarterial embolization is an important tool for the control of head and neck bleeding. Special attention should be given to patients after chemoradiation for cancer. Every effort should be made to control the bleeding because some patients may gain a reasonable lifespan and improved quality of life. LEVEL OF EVIDENCE: 4.


Subject(s)
Catheterization, Peripheral/methods , Embolization, Therapeutic/methods , Head and Neck Neoplasms/complications , Hemorrhage/therapy , Acute Disease , Adult , Aged , Aged, 80 and over , Female , Femoral Artery , Follow-Up Studies , Head and Neck Neoplasms/blood supply , Hemorrhage/etiology , Humans , Male , Middle Aged , Recurrence , Retrospective Studies , Time Factors , Treatment Outcome , Young Adult
7.
Sensors (Basel) ; 12(8): 10067-85, 2012.
Article in English | MEDLINE | ID: mdl-23112588

ABSTRACT

Modern "smart" CMOS sensors have penetrated into various applications, such as surveillance systems, bio-medical applications, digital cameras, cellular phones and many others. Reducing the power of these sensors continuously challenges designers. In this paper, a low power global shutter CMOS image sensor with Wide Dynamic Range (WDR) ability is presented. This sensor features several power reduction techniques, including a dual voltage supply, a selective power down, transistors with different threshold voltages, a non-rationed logic, and a low voltage static memory. A combination of all these approaches has enabled the design of the low voltage "smart" image sensor, which is capable of reaching a remarkable dynamic range, while consuming very low power. The proposed power-saving solutions have allowed the maintenance of the standard architecture of the sensor, reducing both the time and the cost of the design. In order to maintain the image quality, a relation between the sensor performance and power has been analyzed and a mathematical model, describing the sensor Signal to Noise Ratio (SNR) and Dynamic Range (DR) as a function of the power supplies, is proposed. The described sensor was implemented in a 0.18 um CMOS process and successfully tested in the laboratory. An SNR of 48 dB and DR of 96 dB were achieved with a power dissipation of 4.5 nW per pixel.


Subject(s)
Image Processing, Computer-Assisted/instrumentation , Semiconductors , Signal Processing, Computer-Assisted/instrumentation , Equipment Design , Metals/chemistry , Oxides/chemistry , Signal-To-Noise Ratio
8.
Isr Med Assoc J ; 14(6): 354-8, 2012 Jun.
Article in English | MEDLINE | ID: mdl-22891395

ABSTRACT

BACKGROUND: The presence of stones in the common bile duct (CBD) may cause complications such as obstructing jaundice or ascending cholangitis, and the stones should be removed. OBJECTIVES: To assess the efficacy of percutaneous elimination of CBD stones from the gallbladder through the papilla. METHODS: During a 4 year period, six patients (five men and one woman, mean age 71.5 years) who had CBD stones and an existing gallbladder drain underwent percutaneous stone push into the duodenum after balloon dilatation of the papilla, with a diameter equal to that of the largest stone. Access into the CBD was from the gallbladder, using an already existing percutaneous gallbladder drain (cholecystostomy tube). RESULTS: Each patient had one to three CBD stones measuring 7-14 mm. Successful CBD stone elimination into the duodenum was achieved in five of the six patients. The single failure occurred in a patient with choledochal diverticulum, who was operated successfully. There were no major or minor complications during or after the procedures. CONCLUSIONS: Trans-cholecystic CBD stone elimination is a safe and feasible percutaneous technique that utilizes existing tracts, thus obviating the need to create new percutaneous access. This procedure can replace endoscopic or surgical CBD exploration.


Subject(s)
Catheterization/methods , Cholecystostomy , Gallstones/therapy , Adult , Aged, 80 and over , Cholangiography , Female , Gallstones/diagnostic imaging , Humans , Male , Middle Aged , Radiography, Interventional , Treatment Outcome
9.
Pediatr Nephrol ; 27(6): 1037-40, 2012 Jun.
Article in English | MEDLINE | ID: mdl-22366877

ABSTRACT

BACKGROUND: Hyponatremic hypertensive syndrome (HHS) is characterized by unilateral renal artery stenosis with secondary hypertension and glomerular and tubular dysfunction due to hyperfiltration and activation of the renin-angiotensin system (RAS). CASE-DIAGNOSIS/TREATMENT: We describe four children with HHS. All presented with polyuria and polydipsia, electrolyte disturbances, metabolic alkalosis, variable tubular dysfunction, and nephrotic range proteinuria along with hypertension. Interestingly, in one patient, glomerular and tubular abnormalities preceded the development of hypertension. All symptoms resolved after the underlying renal ischemia was corrected by percutaneous angioplasty. CONCLUSION: Hyponatremic hypertensive syndrome may be more common in children than previously thought. Clinicians should be alert of the signs and symptoms because cure is possible with timely diagnosis and treatment.


Subject(s)
Hypertension, Renovascular/etiology , Hyponatremia/etiology , Renal Artery Obstruction/complications , Angioplasty , Biomarkers/blood , Biomarkers/urine , Child, Preschool , Female , Hemodynamics , Humans , Hypertension, Renovascular/diagnosis , Hypertension, Renovascular/metabolism , Hypertension, Renovascular/physiopathology , Hypertension, Renovascular/therapy , Hyponatremia/diagnosis , Hyponatremia/metabolism , Hyponatremia/physiopathology , Hyponatremia/therapy , Infant , Male , Renal Artery Obstruction/diagnosis , Renal Artery Obstruction/metabolism , Renal Artery Obstruction/physiopathology , Renal Artery Obstruction/therapy , Renin-Angiotensin System , Syndrome , Treatment Outcome
10.
Surg Endosc ; 24(12): 3144-8, 2010 Dec.
Article in English | MEDLINE | ID: mdl-20526628

ABSTRACT

BACKGROUND: Accurate localization of small colorectal cancers and polyps during laparoscopic resection may be difficult and requires precise and reliable localization techniques. This study aimed to assess the usefulness of intraoperative ultrasonography (IOUS) combined with retrograde saline instillation in locating small colorectal cancers and polyps during laparoscopically assisted colectomy. METHODS: The study investigated 14 patients with left-sided lesions of the colon and rectum necessitating preoperative marking. During laparoscopically assisted colorectal surgery, the large bowel was filled with saline solution by gravity, then scanned with a 5- to 10-MHz laparoscopic ultrasound probe. RESULTS: In all patients, both polyps and small cancers were clearly detected by IOUS. Furthermore, the technique was found to be easily mastered and performed. The mean detection time was 11 min. Polyps were seen as hypodense masses protruding from the bowel mucosa, whereas invasive cancers had both hypo- and hyperdense regions with sonographically appreciable penetration through bowel layers. CONCLUSION: Intraoperative laparoscopic ultrasonography in conjunction with saline instillation can serve as a useful tool that allows the surgeon to locate small nonpalpable tumors during laparoscopically assisted resection of colorectal cancer.


Subject(s)
Colorectal Neoplasms/diagnostic imaging , Colorectal Neoplasms/surgery , Endosonography , Intraoperative Care/methods , Laparoscopy , Aged , Aged, 80 and over , Feasibility Studies , Female , Humans , Male , Middle Aged , Prospective Studies
11.
AJR Am J Roentgenol ; 194(6): 1626-9, 2010 Jun.
Article in English | MEDLINE | ID: mdl-20489105

ABSTRACT

OBJECTIVE: The purpose of our study was to determine whether pharmacologic thrombolysis with urokinase in the lyse and wait (L&W) technique compared with mechanical declotting using the Arrow-Trerotola percutaneous thrombectomy device is more efficient, safer, or less expensive in treating thrombosed hemodialysis grafts. MATERIALS AND METHODS: The files of 157 patients who underwent arteriovenous graft declotting from 2000 to 2007 at one tertiary care center were reviewed. The study group included 83 women and 74 men with a mean age of 68 +/- 12 years (range, 27-95 years). A total of 563 procedures were performed: 427 with the L&W technique and 136 with mechanical percutaneous thrombectomy using the percutaneous thrombectomy device. The two types of procedures were compared for success rate, complications, average patency time, and cost. RESULTS: There were no statistically significant differences between the pharmacologic and mechanical procedures in immediate success rate (99% and 98%, respectively) or average patency time (5.44 months and 5.40 months, respectively). The L&W technique was considerably less expensive. CONCLUSION: Given its lower cost and equal efficacy and safety, L&W appears to be preferable to mechanical thrombolysis with a percutaneous thrombectomy device for initial arteriovenous hemodialysis graft declotting.


Subject(s)
Arteriovenous Shunt, Surgical , Graft Occlusion, Vascular/therapy , Plasminogen Activators/administration & dosage , Renal Dialysis , Thrombectomy/instrumentation , Thrombolytic Therapy/methods , Thrombosis/therapy , Urokinase-Type Plasminogen Activator/administration & dosage , Adult , Aged , Aged, 80 and over , Female , Graft Occlusion, Vascular/drug therapy , Humans , Male , Middle Aged , Retrospective Studies , Thrombosis/drug therapy , Treatment Outcome , Vascular Patency
12.
Cardiovasc Intervent Radiol ; 33(3): 560-4, 2010 Jun.
Article in English | MEDLINE | ID: mdl-19908088

ABSTRACT

The purpose of this study was to evaluate the effectiveness and safety of transjugular liver biopsy (TJLB) and plugged-percutaneous liver biopsy (PB) in consecutive patients with severe liver disease associated with impaired coagulation, ascites, or both and to verify the in-house protocol used to select the appropriate procedure. In 2000-2006, 329 patients (208 male [62.8%] and 121 female [37.2%]), aged 1 month to 81 years (mean, 46.8 years), underwent 150 TJLBs (39.1%) or 233 PBs (60.9%) procedures at a major tertiary center, as determined by an in-house protocol. The groups were compared for specimen characteristics, technical success, and complications. Technical success rates were 97.4% for TJLB (146/150) and 99.1% for PB (231/233). TJLB was associated with a lower average core length (1.29 vs. 1.43 cm) and lower average number of specimens obtained (2.44 vs. 2.8), but both methods yielded sufficient tissue for a definitive diagnosis. There were no major complications in either group. TJLB and PB can be safely and effectively performed for the diagnosis of hepatic disease in patients with contraindications for standard percutaneous liver biopsy. When both are technically available, we suggest PB as the procedure of choice, especially in transplanted livers.


Subject(s)
Biopsy, Needle/methods , Clinical Protocols , Jugular Veins , Liver Diseases/pathology , Adolescent , Adult , Aged , Aged, 80 and over , Chi-Square Distribution , Child , Child, Preschool , Contraindications , Female , Humans , Infant , Male , Middle Aged , Patient Selection , Postoperative Complications , Radiography, Interventional , Retrospective Studies
13.
Diagn Interv Radiol ; 16(4): 312-4, 2010 Dec.
Article in English | MEDLINE | ID: mdl-19784918

ABSTRACT

We describe a patient after liver transplantation with a preexisting surgical splenorenal shunt close to the confluence of the splenic and superior mesenteric veins and a wide, short communication between the splenic and renal veins. To close the shunt, an inferior vena cava filter was inserted in the shunt and a vascular plug was placed in the splenic vein inside the filter. When this failed to stop the flow through the shunt, a covered stent was deployed at the superior mesenteric vein-portal vein junction.


Subject(s)
Liver Transplantation , Splenorenal Shunt, Surgical , Stents , Adult , Contrast Media , Female , Follow-Up Studies , Humans , Radiographic Image Enhancement , Renal Veins/diagnostic imaging , Renal Veins/surgery , Splenic Vein/diagnostic imaging , Splenic Vein/surgery , Splenomegaly/diagnostic imaging , Tomography, X-Ray Computed , Treatment Outcome , Ultrasonography, Doppler, Color , Vena Cava Filters
14.
Cardiovasc Intervent Radiol ; 32(5): 923-7, 2009 Sep.
Article in English | MEDLINE | ID: mdl-19484291

ABSTRACT

The purpose of this study was to report our experience in elongating short distal necks of descending thoracic aortic aneurysms (DTAAs) by coil embolization of the celiac trunk prior to endovascular aneurysm repair (EVAR). During 6 years seven patients (five men and two women; mean age, 74) who had DTAAs with short distal necks unsuitable for conventional EVAR, and well patent superior and inferior mesenteric arteries based on CT, were treated in one session with EVAR after the celiac trunk was coil embolized to elongate the neck. All patients were followed by CT every 3 months in the first year and every 6 months thereafter. Technical success was achieved in all patients, and no early or late ischemic complications were noted. No procedural complications occurred and good aneurysm sealing was obtained in all patients. Three endoleaks were identified after 3 months (one patient) and 6 months (two patients); all were treated successfully with insertion of an additional stent-graft. In patients with DTAAs who are candidates for EVAR but have short aneurysm distal necks, celiac trunk embolization -- only if the superior and inferior mesenteric arteries are patent -- is a good and safe way to elongate the neck and enable EVAR.


Subject(s)
Aortic Aneurysm, Thoracic/therapy , Celiac Artery , Embolization, Therapeutic/methods , Vascular Surgical Procedures/methods , Aged , Aged, 80 and over , Angiography , Aortic Aneurysm, Thoracic/diagnostic imaging , Female , Humans , Male , Middle Aged , Radiography, Interventional , Stents , Tomography, X-Ray Computed , Treatment Outcome
15.
J Clin Ultrasound ; 37(7): 375-9, 2009 Sep.
Article in English | MEDLINE | ID: mdl-19479717

ABSTRACT

PURPOSE: To assess the accuracy of intraoperative ultrasound (IOUS) as a localizing technique for colorectal resections, and its impact on surgical management. METHODS: Twenty-five patients (15 men and 10 women; mean age, 74.4 years) with early cancers (p T1), or polyps, not amenable to endoscopic removal were selected. IOUS was used as a sole method of intraoperative localization. Its performance was evaluated through review of preoperative colonoscopy reports, intraoperative findings, histopathology reports, and clinical follow-up. RESULTS: The lesions were situated in the cecum (n = 5), ascending colon (n = 3), transverse colon (n = 4), descending colon (n = 7), and rectum (n = 6). IOUS technique allowed correct localization in 24 of 25 patients, visualization of the bowel wall, and its penetration by malignant tumors. In rectal lesions, IOUS showed clearly the tumor and its margin, which facilitated performance sphincter-sparing procedure. CONCLUSION: In patients with small polyps and early cancers of colon and rectum, IOUS may be effectively used as a sole method of intraoperative localization and provide additional information that may alter decision making with regard to surgical technique.


Subject(s)
Colorectal Neoplasms/surgery , Colorectal Surgery/methods , Intestinal Polyps/surgery , Ultrasonography, Interventional/methods , Adenocarcinoma/diagnostic imaging , Adenocarcinoma/surgery , Aged , Cecum/diagnostic imaging , Cecum/pathology , Cecum/surgery , Colonoscopy , Colorectal Neoplasms/diagnostic imaging , Early Diagnosis , Female , Humans , Intestinal Polyps/diagnostic imaging , Intraoperative Period , Male , Prospective Studies , Ultrasonography, Doppler
16.
Transplantation ; 87(5): 734-9, 2009 Mar 15.
Article in English | MEDLINE | ID: mdl-19295319

ABSTRACT

BACKGROUND: Preexisting spontaneous portosystemic shunts increase the risk of posttransplantation portal vein thrombosis. Portosystemic shunts may also be placed surgically to manage posttransplant portal vein stenosis/thrombosis. Both types may be complicated by hepatic encephalopathy. METHODS: The database of a major tertiary medical center from 1999 to 2006 was searched for liver transplant recipients with hepatic encephalopathy and stable liver function. The medical and imaging files were reviewed for risk factors, management, and outcome. RESULTS: Of the 244 patients who underwent liver transplantation during the study period, four (1.6%) met the inclusion criteria. Median age at transplantation was 49 years (range 39-54); median time to the first episode of hepatic encephalopathy after transplantation was 23 months (range 2-40). In two patients, a distal splenorenal shunt placed at 1 and 7 months after transplantation to treat portal vein thrombosis led to hepatic encephalopathy at 1 and 33 months later. Both responded to medical therapy. The other two patients had spontaneous splenorenal shunts, and hepatic encephalopathy appeared 33 months and 12 months after transplantation. Treatment consisted of transhepatic percutaneous portal vein dilatation with stent insertion in the first patient and interposition of a venous graft between the superior mesenteric and left intrahepatic portal veins to reroute splanchnic flow in the second patient. CONCLUSIONS: Portosystemic shunts in liver transplant recipients with stable graft function may be associated with hepatic encephalopathy. Pretransplant assessment to detect unknown spontaneous shunts is important. Restoration of portal flow is the preferred procedure in this setting.


Subject(s)
Hepatic Encephalopathy/etiology , Liver Transplantation/adverse effects , Portasystemic Shunt, Surgical/adverse effects , Biopsy , Humans , Hypertension, Portal/surgery , Liver Transplantation/pathology , Magnetic Resonance Angiography , Portal Vein/pathology , Portography , Splenic Artery/diagnostic imaging , Splenic Artery/pathology , Splenorenal Shunt, Surgical , Thrombosis/pathology
17.
Catheter Cardiovasc Interv ; 74(2): 278-85, 2009 Aug 01.
Article in English | MEDLINE | ID: mdl-19198011

ABSTRACT

OBJECTIVE: To evaluate the feasibility of a new 0.014'' CiTop guidewire to cross total occlusions within normal and diseased blood vessels; proof of concept. BACKGROUND: Despite recent advances, chronic arterial occlusions remain the main obstacle of coronary and peripheral interventions. METHODS: The OVALUM CiTop 0.014'' guidewire is an over-the-wire catheter designed to penetrate through chronic total occlusions (CTO) and allow for further PCI interventions. The CiTop guidewire was tested in normal peripheral and coronary arteries of swine (n = 7) and in totally occluded arterial lesions within human amputations (n = 10). RESULTS: The CiTop 0.014'' guidewire was operated successfully in seven peripheral blood vessels and 12 coronary arteries without angiographic or histological evidence of damage to the arterial wall. The CiTop crossed 9 of the 10 occluded segments within the human amputation with no angiographic or histological evidence of arterial damage (90% success rate). Average time to cross the occlusion was 4.6 +/- 5.6 min. In one artery (10%), angiographic evidence of perforation was noted and there was histological evidence for arterial wall damage. CONCLUSION: Our data show that the new 0.014'' CiTop guidewire can be well operated within normal peripheral and coronary arteries of swine, and with minimal complications within totally occluded blood vessels from human amputations while effectively penetrating and crossing total arterial occlusions.


Subject(s)
Angioplasty, Balloon, Coronary/instrumentation , Angioplasty, Balloon/instrumentation , Arterial Occlusive Diseases/therapy , Coronary Vessels , Lower Extremity/blood supply , Amputation, Surgical , Angioplasty, Balloon/adverse effects , Angioplasty, Balloon, Coronary/adverse effects , Animals , Arterial Occlusive Diseases/diagnostic imaging , Arterial Occlusive Diseases/pathology , Chronic Disease , Constriction, Pathologic , Coronary Angiography , Coronary Vessels/pathology , Equipment Design , Feasibility Studies , Female , Humans , Materials Testing , Pliability , Sus scrofa
18.
Isr Med Assoc J ; 11(10): 611-4, 2009 Oct.
Article in English | MEDLINE | ID: mdl-20077948

ABSTRACT

BACKGROUND: Critical limb ischemia is an increasingly common condition that has high surgical morbidity and limited non-surgical options. OBJECTIVES: To evaluate the use of silicon carbide-coated Motion stents, as compared to reported data for bare metal stents, in elderly patients with infrapopliteal artery stenoses causing critical limb ischemia after failed or complicated percutaneous transluminal angioplasty. METHODS: Between January 2003 and March 2004, 41 stents were inserted into 17 consecutive patients (11 males, 6 females, mean age 82 years, range 75-93) following unsuccessful or complicated PTA. Seven patients had one-vessel run-off, six had two-vessel and four had three vessel run-off. All patients suffered from CLI, had up to three lesions and more than one co-morbid condition, and were considered at high surgical risk. Silicon carbide-coated Motion coronary stents, 2.5-4 mm diameterand 25 and 30 mm length, were used. Pre-intervention assessment included clinical condition, ankle brachial index, Doppler ultrasound and digital subtracted angiography. Postintervention evaluation included clinical condition, ABI and Doppler ultrasound at 3, 6 and 12 months. RESULTS: The technical success rate per lesion was 100% (41/41). Two patients died of unrelated causes after 2 and 8 months respectively. Primary patency rates with duplex ultrasound were 68.7% (11/16) at 3 months, 43.7% (7/16) at 6 months and 40% (6/15) after 12 months. Nine patients developed complete occlusion in 13 stents; three of these patients underwent a below-knee amputation and two patients a partial foot amputation. Re-intervention (PTA only) was performed in 7 patients (43.7%). Secondary patency rate was 81.2% (13/16) at 6 months and 60% (9/15) at one year. Mean ABI index had improved at 6 months from 0.32 to 0.67, and to 0.53 at one year. Clinical improvement was evident in 87.5% (14/16) at 6 months and in 66.6% (10/15) at one year. CONCLUSIONS: Silicon carbide-coated stents are comparable to bare metal stents after 6 and 12 months in infrapopliteal interventions in CLI when stenting is indicated.


Subject(s)
Arterial Occlusive Diseases/therapy , Ischemia/therapy , Leg/blood supply , Peripheral Vascular Diseases/therapy , Popliteal Artery , Stents , Aged , Aged, 80 and over , Angiography, Digital Subtraction , Angioplasty, Balloon , Ankle Brachial Index , Arterial Occlusive Diseases/diagnosis , Carbon Compounds, Inorganic , Coated Materials, Biocompatible , Female , Follow-Up Studies , Humans , Ischemia/diagnosis , Male , Peripheral Vascular Diseases/diagnosis , Silicon Compounds , Treatment Failure , Treatment Outcome , Ultrasonography, Doppler , Vascular Patency
19.
J Vasc Interv Radiol ; 20(2): 259-63, 2009 Feb.
Article in English | MEDLINE | ID: mdl-19097808

ABSTRACT

Hyperammonemia with or without ascites with normal synthetic liver functions after liver transplantation might indicate the presence of anastomotic stenosis of the portal or hepatic vein or the existence of a patent portosystemic shunt. The authors describe six patients, three children after split-liver transplantation and three adults after cadaver liver transplantation, who presented with hyperammonemia. Three patients had ascites. All lesions were successfully treated percutaneously; stents were placed in patients with anastomotic stenoses and coil embolization was performed in patients with patent portosystemic shunts--with either transhepatic or transjugular approaches according to the site of the abnormality. Ammonia levels returned to normal, and ascites had regressed completely for at least 3 months.


Subject(s)
Ascites/etiology , Ascites/surgery , Hyperammonemia/etiology , Hyperammonemia/surgery , Liver Transplantation/adverse effects , Liver Transplantation/diagnostic imaging , Radiography, Interventional/methods , Stents , Adolescent , Adult , Ascites/diagnostic imaging , Blood Vessel Prosthesis , Child , Child, Preschool , Female , Humans , Infant , Male , Middle Aged , Treatment Outcome , Young Adult
20.
J Vasc Interv Radiol ; 20(1): 66-70, 2009 Jan.
Article in English | MEDLINE | ID: mdl-19028115

ABSTRACT

PURPOSE: To assess the primary and secondary patency rates for juxtaanastomotic stenoses, with or without superimposed thromboses, of arteriovenous hemodialysis fistulas treated with angioplasty and to compare it with National Kidney Foundation Dialysis Outcomes Quality Initiative treatment guidelines for stenosed and occluded arteriovenous fistulas (50% primary patency rate at 12 months). MATERIALS AND METHODS: This study was a retrospective analysis, covering a period of 5(1/2) years. Forty-three hemodialysis patients were referred due to secondary fistula dysfunction, and angiography was diagnostic of a juxtaanastomotic lesion. Interventions consisted of standard angioplasty techniques along with thrombolysis and/or thrombectomy and intravascular stent placement as needed. Follow-up was performed at the attending dialysis center, and repeat angiography was performed as clinically required. RESULTS: Immediate postprocedural angiography demonstrated an angiographic success rate of 98%. Clinical success, with at least one session of normal dialysis, occurred in 95% of interventions. Primary patency rates at 12 months for the stenosed and stenosed/thrombosed fistulas were 56% and 64%, respectively. Secondary patency rates at 12 months were 64% and 63%, respectively. Half of the stenosed fistulas were patent at 1.5 years, 28% were patent at 4 years, and 13% remained patent at 6 years. No major complications were documented. Four minor complications, which did not require therapy, were noted. CONCLUSIONS: The results achieved are comparable to those reported for interventions at nonjuxtaanastomotic sites and exceed those quoted by the National Kidney Foundation Dialysis Outcomes Quality Initiative guidelines. Angioplastic interventions in a juxtaanastomatic area of arteriovenous fistulas are safe, promote prolonged patency, and postpone the need for surgical intervention or creation of a new fistula.


Subject(s)
Angioplasty, Balloon , Arteriovenous Shunt, Surgical/adverse effects , Renal Dialysis , Thrombosis/therapy , Upper Extremity/blood supply , Aged , Aged, 80 and over , Angioplasty, Balloon/instrumentation , Constriction, Pathologic , Female , Humans , Male , Middle Aged , Practice Guidelines as Topic , Radiography , Retrospective Studies , Stents , Thrombectomy , Thrombolytic Therapy , Thrombosis/diagnostic imaging , Thrombosis/etiology , Time Factors , Treatment Outcome , Vascular Patency
SELECTION OF CITATIONS
SEARCH DETAIL
...