1.
Nauchnye Doki Vyss Shkoly Biol Nauki
; (7): 68-72, 1987.
Article
in Russian
| MEDLINE
| ID: mdl-3311179
ABSTRACT
After 10 minutes of endotoxin Salmonella typhimurium (1 mg/kg) injection into rabbits thrombocytopenia appeared, the aggregation and secretory function of circulating platelets reduced, the transformation of platelet forms from disk-shaped into spheroidal took place. On the surface of plasmatic membranes the pseudopodies and aggregates examining samples of PRP were observed. Indomethacin, blockator of biosynthesis of prostaglandins results in normalisation of morphofunctional properties of platelets.