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1.
J Neurosurg Pediatr ; 22(3): 313-316, 2018 09.
Article in English | MEDLINE | ID: mdl-29882735

ABSTRACT

A parasitic twin represents a rare developmental anomaly in which an asymmetrical, nonviable conjoined twin is attached to the host body at the time of birth. Rachipagus is among the rarest of conjoined twin subtypes and typically features a parasitic twin mass attached at the spine. Herein, the authors review the literature and describe the case of a 9-month-old girl presenting with a rachipagus parasitic twin consisting of a fully developed set of lower extremities originating from the midline upper back. After a complete workup to delineate parasite and autosite anatomy, the parasitic twin mass was successfully excised by a multidisciplinary team of surgeons, and the resulting defect was closed in a single stage.


Subject(s)
Abnormalities, Severe Teratoid/parasitology , Abnormalities, Severe Teratoid/surgery , Neurosurgical Procedures/methods , Parasites/pathogenicity , Twins, Conjoined/pathology , Twins, Conjoined/surgery , Abnormalities, Severe Teratoid/diagnostic imaging , Animals , Female , Humans , Infant , Magnetic Resonance Imaging , Tomography Scanners, X-Ray Computed
2.
Global Spine J ; 8(2): 114-120, 2018 Apr.
Article in English | MEDLINE | ID: mdl-29662740

ABSTRACT

STUDY DESIGN: Retrospective cohort study. OBJECTIVE: To determine whether a low-density (LD) screw construct can achieve curve correction similar to a high-density (HD) construct in adolescent scoliosis. METHODS: Patients treated operatively for idiopathic scoliosis between 2007 and 2011 were identified through a database review. A consistent LD screw construct was used. Radiographic assessment included percent correction of major and fractional lumbar curves, T5-T12 kyphosis, and angle of lowest instrumented vertebra (LIV). Costs were compared with HD constructs. RESULTS: Thirty-five patients were included in the analysis. Ages ranged from 12 to 19 years (mean = 14.9 years). Average screw density was 1.2 screws per level (range = 1.07-1.5 screws). Mean percent curve correction at latest follow-up: major curve, 66.9%; fractional lumbar curve, 63%. Average postoperative thoracic kyphosis: 29.5°. Mean LIV angle: 5.6°. Average construct cost was $14 871 per case compared with $23 840 per case if all levels had been instrumented with 2 screws, amounting to an average savings of $9000. CONCLUSIONS: Our LD screw construct is among the lowest density constructs reported and achieves curve correction comparable to HD constructs at substantially lower cost.

3.
J Orthop Trauma ; 31(1): 37-46, 2017 Jan.
Article in English | MEDLINE | ID: mdl-27997465

ABSTRACT

OBJECTIVE: We sought to determine the role of lumbopelvic fixation (LPF) in the treatment of zone II sacral fractures with varying levels of sacral comminution combined with anterior pelvic ring (PR) instability. We also sought to determine the proximal extent of LPF necessary for adequate stabilization and the role of LPF in complex sacral fractures when only 1 transiliac-transsacral (TI-TS) screw is feasible. MATERIALS AND METHODS: Fifteen L4 to pelvis fresh-frozen cadaveric specimens were tested intact in flexion-extension (FE) and axial rotation (AR) in a bilateral stance gliding hip model. Two comminution severities were simulated through the sacral foramen using an oscillating saw, with either a single vertical fracture (small gap, 1 mm) or 2 vertical fractures 10 mm apart with the intermediary bone removed (large gap). We assessed sacral fracture zone (SZ), PR, and total lumbopelvic (TL) stability during FE and AR. The following variables were tested: (1) presence of transverse cross-connector, (2) presence of anterior plate, (3) extent of LPF (L4 vs. L5), (4) fracture gap size (small vs. large), (5) number of TI-TS screws (1 vs. 2). RESULTS: The transverse cross-connector and anterior plate significantly increased PR stability during AR (P = 0.02 and P = 0.01, respectively). Increased sacral comminution significantly affected SZ stability during FE (P = 0.01). Two versus 1 TI-TS screw in a large-gap model significantly affected TL stability (P = 0.04) and trended toward increased SZ stabilization during FE (P = 0.08). Addition of LPF (L4 and L5) significantly improved SZ and TL stability during AR and FE (P < 0.05). LPF in combination with TI-TS screws resulted in the least amount of motion across all 3 zones (SZ, PR, and TL) compared with all other constructs in both small-gap and large-gap models. CONCLUSIONS: The role of LPF in the treatment of complex sacral fractures is supported, especially in the setting of sacral comminution. LPF with proximal fixation at L4 in a hybrid approach might be needed in highly comminuted cases and when only 1 TI-TS screw is feasible to obtain maximum biomechanical support across the fracture zone.


Subject(s)
Fracture Fixation, Internal/methods , Lumbar Vertebrae/surgery , Sacrum/injuries , Sacrum/physiopathology , Spinal Fractures/physiopathology , Spinal Fractures/surgery , Bone Screws , Cadaver , Female , Fracture Fixation, Internal/instrumentation , Humans , Male , Motion , Range of Motion, Articular , Sacrum/surgery , Spinal Fractures/diagnosis , Treatment Outcome
4.
Eur Spine J ; 25(3): 795-800, 2016 Mar.
Article in English | MEDLINE | ID: mdl-26148567

ABSTRACT

PURPOSE: A prospective, longitudinal cohort was studied to determine the incidence, consequences, and risk factors of major perioperative complications in patients with cerebral palsy (CP) treated with spinal fusion. There is a wide variety of data available on the complications of spine surgery; however, little exists on the perioperative complications in patients with CP. METHODS: A prospective multicenter dataset of consecutive patients with CP treated with spinal fusion was evaluated. All major perioperative complications were identified and stratified into categories: pulmonary, gastrointestinal, other medical, wound infection, neurological, instrumentation related, and unplanned staged surgery. Univariate and multivariate analyses were performed to identify various risk factors for major perioperative complications. RESULTS: 127 patients were identified with a mean age of 14.3 ± 2.6 years. Overall, 39.4% of the patients had a major perioperative complication. Occurrence of a complication [no complication (NC), yes complication (YC)] resulted in significantly increased intensive care unit (ICU) (NC = 3.2 days, YC = 7.8 days, p < 0.05) and hospital stays (NC = 7.7 days, YC = 15.6 days, p < 0.05). Variables associated with greater risk of a complication included: increased estimated blood loss (EBL) (p < 0.001), larger preoperative kyphosis (p = 0.05), staged procedures (p < 0.05), a lack of antifibrinolytic use (p < 0.05), and a trend toward lower body mass index (BMI) (p = 0.08). Multivariate regression analysis revealed an increased EBL as independently associated with a major perioperative complication (p < 0.05). CONCLUSIONS: In this cohort of patients with CP who underwent spinal fusion, 39.4% experienced a major perioperative complication, with pulmonary being the most common. The occurrence of a major perioperative complication lengthened both ICU and hospital stay. Risk factors for major perioperative complications included greater preoperative kyphosis, staged procedures, a lack of antifibrinolytic use, and increased EBL, with the latter being an independent predictor of a major perioperative complication. LEVEL OF EVIDENCE: 2.


Subject(s)
Cerebral Palsy/surgery , Spinal Fusion/adverse effects , Adolescent , Cerebral Palsy/complications , Child , Female , Humans , Incidence , Kyphosis/etiology , Length of Stay/statistics & numerical data , Male , Multivariate Analysis , Postoperative Complications/etiology , Prospective Studies , Respiratory Tract Diseases/etiology , Retrospective Studies , Risk Factors , Spinal Fusion/methods
5.
Obstet Gynecol ; 122(2 Pt 2): 452-455, 2013 Aug.
Article in English | MEDLINE | ID: mdl-23884257

ABSTRACT

BACKGROUND: Pyoderma gangrenosum is a rare dermatologic disorder that can occur on the vulva. CASE: A 25-year-old woman, gravida 2 para 1 abortus 1, had development of pain and subsequent ulceration at the location of her previously healed vulvar obstetric laceration. The ulceration and pain continued to worsen despite wound management. Once the diagnosis of vulvar pyoderma gangrenosum was made, cyclosporine was started and the wound rapidly healed. CONCLUSION: Vulvar pyoderma gangrenosum should be considered when a vulvar wound is not healing with conservative measures. Cyclosporine can be considered as an alternative to steroids for treatment.


Subject(s)
Pyoderma Gangrenosum/etiology , Vulvar Diseases/etiology , Adult , Cyclosporine/therapeutic use , Delivery, Obstetric/adverse effects , Dermatologic Agents/therapeutic use , Female , Humans , Lacerations/complications , Pyoderma Gangrenosum/drug therapy , Vulva/injuries , Vulvar Diseases/drug therapy , Wound Healing
6.
Spine (Phila Pa 1976) ; 38(21): 1842-7, 2013 Oct 01.
Article in English | MEDLINE | ID: mdl-23873241

ABSTRACT

STUDY DESIGN: Prospective, longitudinal cohort. OBJECTIVE: To evaluate the incidence, timing, and risk factors for reoperation in patients with adolescent idiopathic scoliosis (AIS) treated with pedicle screws (PSs) compared with hybrid (Hb) constructs. SUMMARY OF BACKGROUND DATA: Rates of return to the operating room (OR) after definitive fusion for AIS vary, with a paucity of data on PS constructs. METHODS: A prospective multicenter database was retrospectively queried to identify consecutive patients with AIS who underwent posterior spinal fusion with either PS or Hb constructs with a minimum 2-year follow-up. All reoperations were stratified into an early group (<60 d) or a late group (>60 d). Univariate and multivariate logistical analyses were performed to identify potential risk factors related to reoperation. RESULTS: A total of 627 patients met the inclusion criteria (PS = 540, Hb = 87). There was a statistically significant difference in the rate of reoperations between the PS (3.5%) and Hb groups (12.6%), P < 0.001. Early return to the OR occurred in 2.0% of the patients with PS compared with 3.4% in the Hb group, P = 0.43. Late returns to the OR occurred in 1.5% of PS group versus 9.2% of the Hb group, P < 0.001. Multivariate analysis revealed longer operating time as an independent risk factor for an unplanned return to the OR in patients treated with PSs (P < 0.05). CONCLUSION: Our results suggest that patients with AIS treated with PS have decreased rates of unplanned return to the OR when compared with patients with Hb constructs. The majority of returns to the OR were early (<60 d) for the PS group compared with late (>60 d) for the Hb group. Longer operative times increased the risk of unplanned reoperation for the PS group. LEVEL OF EVIDENCE: 3.


Subject(s)
Bone Screws , Reoperation/statistics & numerical data , Scoliosis/surgery , Spinal Fusion/methods , Adolescent , Female , Humans , Logistic Models , Male , Multivariate Analysis , Operating Rooms/statistics & numerical data , Prospective Studies , Retrospective Studies , Risk Factors , Spinal Fusion/instrumentation , Time Factors
9.
Cutis ; 71(1): 68-70, 2003 Jan.
Article in English | MEDLINE | ID: mdl-12553633

ABSTRACT

Compensatory hyperhidrosis is a common and potentially severe side effect of bilateral endoscopic thoracic sympathectomy. We describe a patient with severe compensatory hyperhidrosis as a result of this procedure. We treated the patient with 2 separate series of subcutaneous botulinum toxin type A injections to the right upper abdomen and achieved anhidrosis in 5 weeks. Although botulinum toxin is already an established treatment modality for primary hyperhidrosis, there is little experience using it for the treatment of compensatory hyperhidrosis. Because of its efficacy and low side-effect profile, we believe botulinum toxin may play a significant role in treating compensatory hyperhidrosis as a first-line agent.


Subject(s)
Botulinum Toxins, Type A/therapeutic use , Hyperhidrosis/drug therapy , Neuromuscular Agents/therapeutic use , Adult , Botulinum Toxins, Type A/administration & dosage , Humans , Hyperhidrosis/pathology , Injections, Subcutaneous , Male , Neuromuscular Agents/administration & dosage
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