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1.
Appl Environ Microbiol ; 62(9): 3466-9, 1996 Sep.
Article in English | MEDLINE | ID: mdl-8795239

ABSTRACT

Municipal sewage was screened for DNA encoding Shiga-like Toxin (SLT) II, a key protein involved in the virulence of enterohemorrhagic Escherichia coli. PCR analysis of sewage concentrates showed that DNA encoding SLT II was present in a single sample of untreated sewage and absent in all other samples tested (n = 6). Thermotolerant E. coli cultured from the sewage (n = 1,520) also tested negative for SLT II by colony hybridization.


Subject(s)
Bacterial Toxins/genetics , DNA, Bacterial/analysis , Escherichia coli/isolation & purification , Gastrointestinal Hemorrhage/microbiology , Sewage , Water Microbiology , Escherichia coli/pathogenicity , Shiga Toxin 1 , Shiga Toxin 2
2.
J Urol (Paris) ; 102(4): 161-7, 1996.
Article in French | MEDLINE | ID: mdl-9091566

ABSTRACT

We report a case of bilateral 2,8 dihydroxyadenine urolithiasis in a 25-year-old woman, born from an incestuous union between a brother and sister, who developed the first manifestations at the age of 9 years. This condition results from APRTase deficiency and an autosomal recessive inherited disorder. Diagnosis requires physical analysis of the stones and measurement of APRT activity in red cells. Treatment by lithotripsy with piezo-electric shock waves was ineffective on the left leading to eventual nephrectomy. The right lithiasis was destroyed by lithotripsy. This result would suggest variable solidity of 2,8 dihydroxyadenine stones. In this patient, an indwelling endoprosthesis was left in place for 14 months for extra-medical reasons and led to staphylococcal urinary infections, struvite lithiasis and incrustations of the catheter within the bladder. Ureteroscopy and percutaneous nephrostomy were required to remove this secondary radio-opaque stone.


Subject(s)
Adenine/analogs & derivatives , Kidney Calculi/therapy , Lithotripsy/methods , Nephrostomy, Percutaneous/methods , Ureteral Calculi/therapy , Adenine/chemistry , Adult , Female , Humans , Kidney Calculi/chemistry , Kidney Calculi/congenital , Kidney Calculi/diagnostic imaging , Nephrectomy , Tomography, X-Ray Computed , Ureteral Calculi/chemistry , Ureteral Calculi/congenital , Ureteral Calculi/diagnostic imaging
3.
Rev Rhum Engl Ed ; 62(6): 459-61, 1995 Jun.
Article in English | MEDLINE | ID: mdl-7552212

ABSTRACT

A case of polyarthritis following intravesical administration of bacillus Calmette-Guérin (BCG) for bladder carcinoma is reported in a patient with long-standing ankylosing spondylitis. Possible links between BCG-therapy and joint manifestations are discussed in the light of data from the literature. Patients who develop joint manifestations after BCG-therapy are often HLA B27-positive.


Subject(s)
Arthritis/etiology , BCG Vaccine/adverse effects , Carcinoma/therapy , Spondylitis, Ankylosing/complications , Urinary Bladder Neoplasms/therapy , Acute Disease , Aged , Arthritis/diagnosis , Carcinoma/complications , HLA-B27 Antigen/analysis , Humans , Male , Urinary Bladder Neoplasms/complications
4.
Ann Urol (Paris) ; 26(1): 20-3, 1992.
Article in French | MEDLINE | ID: mdl-1558368

ABSTRACT

The ovarian vein syndrome is due to ureteral compression caused by a dilated ovarian vein. The authors describe the clinical case of a young ten-week pregnant woman in whom the ovarian vein syndrome was revealed by a pain in the lower right quadrant of the abdomen associated with fever. Excretory urography, retrograde uretero pyelography and computed tomographic examination were performed. The principal clinical and radiological aspects of this syndrome are discussed.


Subject(s)
Ovary/blood supply , Pregnancy Complications , Ureteral Obstruction/etiology , Adult , Diagnosis, Differential , Dilatation, Pathologic/complications , Female , Humans , Pregnancy , Vascular Diseases/complications , Veins
5.
J Urol (Paris) ; 97(3): 150-4, 1991.
Article in French | MEDLINE | ID: mdl-1940429

ABSTRACT

A case of a tumor of the urinary tract discovered after renal trauma is reported. The clinical and radiolocal observations are presented as well as the interest of this case in forensic medicine. A review of the legal aspects recalls the principles of imputability in cases of cancer and trauma. While malignant tumors discovered after renal trauma are often renal cancers, urinary tract tumors can also be revealed after renal trauma. This unfrequent circumstance of discovery underlines the importance of control urography in cases of renal trauma, of history taking (smoking), and of the requirement for follow-up investigations if intra-luminal urographic abnormalities persist without damage to the renal parenchyma on the CAT scan.


Subject(s)
Kidney/injuries , Ureteral Neoplasms/diagnostic imaging , Adult , Angiography , France , Humans , Jurisprudence , Male , Malpractice , Nephrectomy , Tomography, X-Ray Computed , Ureteral Neoplasms/surgery , Urography
7.
J Chir (Paris) ; 127(10): 468-71, 1990 Oct.
Article in French | MEDLINE | ID: mdl-2262522

ABSTRACT

The authors describes a case of posterior dislocation of the elbow in the extreme stage, associating total destruction of the capsule and ligaments, a total arterial lesion, elongation of the median nerve and the opening of the focus at Tscherne's stage III. This case allows considering the biomechanical aspects of dislocation of the elbow and updating the principles of its management.


Subject(s)
Elbow Injuries , Joint Dislocations/surgery , Elbow Joint/diagnostic imaging , Elbow Joint/surgery , Female , Humans , Joint Dislocations/diagnostic imaging , Joint Dislocations/pathology , Radiography
8.
Arch Fr Pediatr ; 46(9): 671-3, 1989 Nov.
Article in French | MEDLINE | ID: mdl-2604528

ABSTRACT

A case of hemoperitoneum secondary to the rupture of an ovarian cyst is reported in a 14 1/2 year-old girl. The severity of the bleeding was explained by anticoagulant therapy given during the previous 3 weeks for laceration of ankle ligaments which necessitated surgery. In this age group, the differential diagnosis with a ruptured ectopic pregnancy had to be considered. The relative prevalence (10%) of complications associated with antivitamin K administration is discussed.


Subject(s)
Anemia/etiology , Ovarian Cysts/complications , Vitamin K/antagonists & inhibitors , 4-Hydroxycoumarins , Acute Disease , Adolescent , Anemia/chemically induced , Anticoagulants/adverse effects , Female , Humans , Indenes , Rupture, Spontaneous , Vitamin K/adverse effects
11.
Toxicol Ind Health ; 1(4): 235-48, 1985 Dec.
Article in English | MEDLINE | ID: mdl-3843504

ABSTRACT

EPA is faced with the need to perform health risk assessments of environmental materials containing mixtures of chlorinated dioxins and -dibenzofurans. Preferably, such an assessment must be based on the direct evaluation of chronic health effects of the mixture or on a knowledge of the toxic effects of each of the components. In the absence of such data, the authors have developed two pragmatic approaches that can reasonably be applied to mixtures such as flyash or contaminated soil. The details of these approaches, viewed as interim procedures, are compared and contrasted with those used by other regulatory and public health authorities.


Subject(s)
Benzofurans/toxicity , Dioxins/toxicity , Animals , Benzofurans/metabolism , Dioxins/metabolism , Humans , Industrial Waste/analysis , Polychlorinated Dibenzodioxins/analysis , Polychlorinated Dibenzodioxins/toxicity , Risk , Stereoisomerism , United States , United States Environmental Protection Agency
13.
Biochim Biophys Acta ; 448(4): 551-61, 1976 Nov 02.
Article in English | MEDLINE | ID: mdl-974146

ABSTRACT

The thermodynamic parameters which define transport of nonelectrolytes through bovine articular cartilage membranes were evaluated. H3HO, glucose and sucrose were used as permeants. These solutes permeate more readily through the upper layers (near the articular surface) than through the denser deeper layers approaching bone. Cartilage is similar in many respects to a swollen cellulose gel. Viscous-flow contributes importantly to transport within cartilage thus greatly enhancing the movement of nutrients.


Subject(s)
Cartilage, Articular/metabolism , Cell Membrane/metabolism , Animals , Biological Transport , Cattle , Glucose/metabolism , Kinetics , Mathematics , Osmotic Pressure , Permeability , Sucrose/metabolism , Tritium , Water/metabolism
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