ABSTRACT
A quantitation of megakaryocytes in normal bone marrow biopsies was performed using a simple direct method of counting. In bone marrow biopsies having a mean cellularity of 72% (range of 60% to 85%), the mean number of megakaryocytes per high-power field (450 X) was 1.5 (range of 0.4 to 2.7).
Subject(s)
Bone Marrow Cells , Megakaryocytes/cytology , Adolescent , Adult , Aged , Aged, 80 and over , Biopsy, Needle , Cell Count , Child , Female , Humans , Male , Middle AgedABSTRACT
In February 1982, a four-year-old Nevada girl with acute lymphoblastic leukemia in remission was hospitalized with fulminant pneumonia and died eight days later at a hospital in California. An influenza virus was the only pathogen detected, and was present in both antemortem and postmortem specimens. The virus was closely related antigenically to A/New Jersey/8/76 (H1N1) and had a genome very similar to a contemporary enzootic swine influenza virus. The patient had had no known contact with swine, and the source of infection could not be determined. Only five possible secondary cases could be detected by retrospective investigation of 62 contacts, and there was no evidence of spread to the general community. Swine influenza viruses circulate among pigs in the United States annually, and it is likely that sporadic transmissions to humans will continue to be detected. Nevertheless, person-to-person spread under these circumstances appears to be limited.
Subject(s)
Influenza A virus/isolation & purification , Orthomyxoviridae Infections/transmission , Adolescent , Adult , Aged , Animals , Child , Child, Preschool , Dogs , Epidemiologic Methods , Female , Hemagglutination, Viral , Humans , Immunosuppression Therapy , Infant , Male , Middle Aged , Orthomyxoviridae Infections/complications , Pneumonia, Pneumocystis/complications , Pneumonia, Pneumocystis/physiopathologyABSTRACT
A light-microscopic examination of sections of kidneys from 35 patients was performed utilizing the PAS stain. A previously unrecognized anatomic network of the basement membrane of the loop of Henle is described. The network consists of 10-to 15-mu-diameter, round-to-ovoid, disk-like areas of thickening of the basement membrane occurring along most loops of Henle and appearing to be present on both thin and thick portions. These disks are present around the entire circumference of the tubule and are separated by areas of 5 to 10 mu of nonthickened basement membranes. Their function, if any, is not presently understood.
Subject(s)
Kidney Tubules/anatomy & histology , Loop of Henle/anatomy & histology , Adolescent , Adult , Aged , Child , Female , Humans , Loop of Henle/ultrastructure , Male , Microscopy, Electron , Middle Aged , Periodic Acid-Schiff ReactionABSTRACT
A correlation of the enumeration of platelets in peripheral smears with platelet counts performed by a direct method is presented. A ratio of 1 platelet per oil-immersion field for every 21,000 platelets of the chamber count indicates the normal average range of platelets to be approximately 7--21 per oil-immersion field.
