ABSTRACT
This article reviews the literature concerning the possibility of using magnetic resonance imaging (MRI) with different field strengths to detect the central vein sign (CVS). CVS is a relatively new and promising symptom of multiple sclerosis (MS). This symptom is a parenchymal vein visualized with the help of special MRI modes, which is localized in the focus of demyelination. Studies show that CVS has a high sensitivity and specificity in the diagnosis of MS, allowing the differentiation from other demyelinating, vascular, systemic diseases. However, most studies in this direction have been done using different MR-sequences and on tomographs with different field strengths, so the purpose of this review is to summarize and compare the results of various studies, which may be of practical benefit to clinicians.
