[Characteristics of surgical approach using for patients with renal cell carcinoma, complicated by postcava tumor thrombosis].

The postcava tumor thrombosis had about 1/3 of patients with renal cell carcinoma at the initial examination. Reconstructive interventions were performed on the postcava for 38 patients (24 men, 14 women). The postcava thrombectomy was applied in 15 patients. The thrombectomy with postcava resection were carried out in 13 patients and plasty- in 6, prosthetics-in 4. An actuarial 3-year or 5-year survival rate of patients consisted of 59.4% and 42.2%. The performance of reconstructive interventions on postcava with its involvement was justified and provided satisfactory results in patients with renal cell carcinoma.

[Effect of phenibut on the respiratory arrest caused by serotonin].

The role of the GABAergic system in mechanisms of the respiratory arrest caused by serotonin administration was studied in anaesthetized rats. Under normal conditions, the systemic administration of serotonin (20-60 mg/kg, i.v.) resulted in drastic changes of the respiratory pattern, whereby the initial phase of increased respiratory rate was followed by the respiratory arrest. The preliminary injection of phenibut (400 mg/kg, i.p.) abolished or sharply reduced the duration of the respiratory arrest phase induced by serotonin. Bilateral vagotomy following the phenibut injection potentiated the anti-apnoesic effect of phenibut, which was evidence of the additive action of vagotomy and phenibut administration. The mechanism of apnea caused by serotonin administration is suggested to include a central GABAergic element, which is activated by phenibut so as to counteract the respiratory arrest.

[Radionuclide visualization of reparative osteogenesis after obliteration of the paranasal sinuses with bio-compositional implants]. / Radionuklidnaia vizualizatsiia protsessa reparativnogo osteogeneza posle obliteratsii okolonosovykh pazukh biokompozitsionnymi implantami.

18 patients with chronic recurrent inflammation and traumatic defects of the paranasal sinuses have undergone obliteration of the sinuses with biocompositional materials (hydroxyapatite and colapol) and plastic reconstruction of the bone defects with metal ceramics. Control of the repair processes with emission computed tomography registered accumulation of radiopharmaceuticals (RP) in the obliteration zone a week after the operation. Four-six weeks later RP homogeneously filled the obliteration zone. Six-twelve months after the obliteration, metabolism in the implant is close to that in the intact tissue. It is concluded that emission computed tomography can follow up metabolic changes in the implant and assess efficiency of the operation.

[The experience of using a method of radionuclide skeletal visualization in the diagnosis of temporomandibular joint diseases]. / Opyt primeneniia metoda radionuklidnoi vizualizatsii skeleta v diagnostike zabolevanii visochno-nizhnecheliustnogo sustava.

The technique was applied in 12 patients with temporomandibular joint dysfunction without X-ray features of arthrosis, and in 7 patients with facial pains of unclear etiology. Radionuclide investigation data compared with clinical and X-ray data, the new technique proved highly sensitive to detect early stages of temporomandibular joint arthrosis and to determine temporomandibular joint involvement in cases of facial pains. This suggests the use of the technique for screening in prosopalgia.