ABSTRACT
The results of combined treatment of 385 cancer recti patients, of whom 202 -- using the staged tactics and chemotherapy, using modified methods of pelvic evisceration and reconstructive-restoration operations with extended lymph node dissection, were analyzed. The main syndromes, characteristic for locally-spread cancer recti are delineated, the surgical treatment concept for this pathology was formulated. The combined approach application had promoted the radical and cytoreductive operations performance rate enhancement, the reduction of palliative operations performance rate, as well as severe complications (hemorrhage and anastomotic sutures insufficiency) occurrence rate, total complications rate -- by 3.8% and lethality -- by 1.9%.
Subject(s)
Colectomy/methods , Colonic Neoplasms/surgery , Anastomosis, Surgical/methods , Animals , Colonic Neoplasms/epidemiology , Colonic Neoplasms/pathology , Disease-Free Survival , Female , Humans , Male , Neoplasm Invasiveness , Neoplasm Staging , Postoperative Complications/epidemiology , Postoperative Complications/etiology , Rats , Rats, WistarABSTRACT
Shown in the paper is a possibility of surgical correction of disturbances in the intestinal phase of gastric secretion in treating peptic ulcer and its complications which are encountered in an overwhelming majority of patients. Sympathectomy of relevant vascular trees is regarded as a pathogenetically validated procedure as is correction of duodenal motility combined with selective proximal vagotomy and excision of the ulcer. It is shown that truncal and selective vagotomy can aggravate the existing disorders of the intestinal phase of gastric secretion.