ABSTRACT
Aim: The purpose of the study is to evaluate and compare the effectiveness of rice husk extract mouthwash (RHM) and Kidodent mouthwash (KM) for reduction in salivary Streptococcus mutans count. Materials and methods: After approval from institutional review board and institutional informed consent, 45 children who met the inclusion criteria were divided into three groups. In group A, children received rice husk mouth wash whereas in group B placebo is specified and in group C, intervention being KM. The unstimulated saliva is collected at baseline, 7th, 10th, and 15th days and subjected to microbiological analysis. The data are statistically analyzed using one-way ANOVA and repeated measures analysis of variance (ANOVA). Results: Rice husk mouthwash showed equivalent, significant, and effective reduction in S. mutans count similar to KM (p < 0.05). Conclusion: The rice husk mouthwash showed potential therapeutic effect in reduction of S. mutans.Clinical trial registry india (CTRI No) : CTRI/2020/10/028594. How to cite this article: Havale R, Rao DG, Bemalgi N, et al. Comparative Evaluation of Novel Herbal Rice Husk Mouthwash with Kidodent against Streptococcus mutans: A Parallel Double-blinded Randomized Control Trial. Int J Clin Pediatr Dent 2022;15(3):356-361.
ABSTRACT
AIM: To compare the antibacterial efficacy of Kidodent, Probiotics, and Carica papaya Leaf extract mouthwashes in reducing Streptococcus mutans count in 8-12 years' old school children. METHODOLOGY: Sixty children of age group of 8-12 years were nominated and grouped as Group A (Kidodent mouthwash), Group B (probiotics mouthwash) Group C (C. papaya leaf extract mouthwash), and Group D (distilled water placebo). Probiotics sachets (Prebact) of about 1 g were diluted in 10 ml of water and given as mouthwash. C. papaya leaf extract was obtained by Soxhlet extraction using ethanol as a solvent. Participants were asked to rinse with mouthwashes for 30 s once daily for up to 15 days. Saliva samples were collected and inoculated using Salivarius Mitis and Agar Agar Type I at 38°C for 24 h and incubated, later colony-forming units per milliliter were determined by serial dilution and calculated using colony counter manually. Statistical Analysis: Data were statistically analyzed using the one-way ANOVA and t-test using the SPSS V.20 software. RESULTS: Probiotics and C. papaya leaf extract mouthwashes were equally effective as Kidodent in reducing S. mutans count in saliva. CONCLUSION: Probiotics and C. papaya leaf extract mouthwashes manifested potential efficacy in reduction of S. mutans.
